MGC87631 Blocking Peptide
- Known as:
- MGC87631 Blocking Peptide
- Catalog number:
- 33r-9467
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- Fitzgerald industries international
- Gene target:
- MGC87631 Blocking Peptide
Related genes to: MGC87631 Blocking Peptide
- Gene:
- CCDC144NL NIH gene
- Name:
- coiled-coil domain containing 144 family, N-terminal like
- Previous symbol:
- -
- Synonyms:
- MGC87631
- Chromosome:
- 17p11.2
- Locus Type:
- gene with protein product
- Date approved:
- 2009-01-15
- Date modifiied:
- 2014-11-19
Related products to: MGC87631 Blocking Peptide
Related articles to: MGC87631 Blocking Peptide
- The focal adhesion is a key pathway for cellular proliferation and migration. This study aimed to elucidate the function of VAV2, a key guanine nucleotide exchange factor in the focal adhesion pathway, and to investigate its post-transcriptional relationships through the predicted VAV2/miRNA/lncRNA network in Laryngeal Squamous Cell Carcinoma (LSCC). - Source: PubMed
Publication date: 2026/05/27
Mohammadi PayamParvaz NajmehMehdiKhani FaribaElahimanesh MohammadBakhshandeh MasoomehAghazadeh KeyvanTabar Mohsen AryanShabani MohammadNajafi Mohammad - Gastric cancer (GC) represents a global healthcare challenge. Recently, many competing endogenous RNA (ceRNA) network studies have elucidated critical long noncoding RNAs (lncRNAs) as potential prognostic biomarkers in GC. Since there is no systematic review and meta-analysis regarding the lncRNAs as ceRNA in GC, we propose the current study. - Source: PubMed
Publication date: 2025/11/28
Salehi-Mazandarani SadraDonyavi Mohammad HosseinVedaei AmirhosseinNajimi AlirezaFarajzadegan ZibaNikpour Parvaneh - Recent research has shown that long noncoding RNA (lncRNA) performs a critical regulatory function across multiple malignancies. The involvement of RNA in the progression of multiple human cancer types has been elucidated; however, there is limited understanding regarding the importance of the lncRNA CCDC144NL-AS1 in cervical carcinoma (CC). - Source: PubMed
Publication date: 2025/04/08
Hu XuemeiWang YulongGuo HongyuGuo Yuzhen - Head and Neck Squamous Cell Carcinoma (HNSCC) is a malignancy characterized by a high incidence and recurrence rate. 5-methylcytosine (mC) RNA modification is a common alteration affecting cancer progression; however, how mC operates within the tumor microenvironment of HNSCC remains to be elucidated. - Source: PubMed
Publication date: 2024/07/16
Lin GongbiaoCai HaoxiHong YihongYao MinYe WeiweiLi WenzhiLiang WentaoFeng ShiqiangLv YunxiaYe HuiCai ChengfuCai Gengming - A growing number of studies have suggested the involvement of long non-coding RNAs as the key players in not just the initiation and progression of the tumor microenvironment, but also in chemotherapy tolerance. In the present study, generated 5-FU-resistant SW480/DR cells were analyzed via cDNA microarray for its aberrant lncRNAs and mRNAs expression in comparison with the 5-FU-susceptible SW480/DS cells. Among the 126 lncRNAs described, lncRNAs , , and have been identified to be significantly upregulated, while lncRNs , , and have been found to be significantly downregulated. In the meantime, bioinformatic analysis through gene ontology studies of aberrantly expressed mRNAs revealed "regulated exocytosis", among others, as the biological process most impacted in SW480/DR cells. To investigate, exosome purification was then carried out and its characterization were validated via transmission electron microscopy and nanoparticle tracking analysis. Interestingly, it was determined that the 5-FU-resistant SW480/DR cells secretes significantly higher concentration of extracellular vesicles, particularly, exosomes when compared to the 5-FU-susceptible SW480/DS cells. Based on the lncRNA-mRNA interaction network analysis generated, lncRNA and have been identified to be potentially involved in the incidence of 5-FU resistance in SW480 colon cancer cells through promoting increased release of exosomes into the intercellular matrix. Our study hopes not only to provide insights on the list of involved candidate lncRNAs, but also to elucidate the role exosomes play in the initiation and development of 5-FU chemotherapy resistance in colon cancer cells. - Source: PubMed
Publication date: 2024/04/15
Azwar ShaminNg Chin TatZahari Sham Siti YazminSeow Heng FongChai MinhianGhazali Mohd FaizalJabar Mohd Faisal