Ask about this productRelated genes to: MARCO Blocking Peptide
- Gene:
- MARCO NIH gene
- Name:
- macrophage receptor with collagenous structure
- Previous symbol:
- -
- Synonyms:
- SCARA2, SR-A6
- Chromosome:
- 2q14.2
- Locus Type:
- gene with protein product
- Date approved:
- 1998-11-26
- Date modifiied:
- 2017-02-28
Related products to: MARCO Blocking Peptide
Related articles to: MARCO Blocking Peptide
- Central nervous system (CNS) infections are associated with high morbidity and mortality, and their management is challenged by antimicrobial resistance and limited cerebrospinal fluid (CSF) penetration of many antibiotics. Intravenous fosfomycin (FOS) offers broad-spectrum activity, favourable pharmacokinetics and reliable CSF penetration, making it a potential partner in combination therapy for severe CNS infections. This interim subgroup analysis of the prospective FORTRESS study evaluated real-world treatment patterns, effectiveness and safety of FOS in patients with CNS infections. - Source: PubMed
Publication date: 2026/06/13
Jarczak DominikKluge StefanKieninger MartinHagel StefanPletz Mathias WZoller MichaelSpies ClaudiaKintrup SebastianAntonitsch LukasZundel JörgDel Bono ValerioGalfo ValentinaFalcone MarcoIasonidou ChristinaSarmati LoredanaCampogiani LauraBal Abhijit MDimopoulos GeorgeVossen Matthias GMastroianni Claudio MBodmann Klaus-FriedrichHerbst CarinaMayer Christian - This study develops Wire Arc Additively Manufactured (WAAM) Nickel-Stainless Steel bimetallic samples with silicon enhancement and investigates their face-milling machinability using a hybrid multi-criteria optimization framework. Seventeen machining trials were designed and conducted using a Response Surface Methodology (RSM)-based Central Composite Design (CCD) to evaluate the effects of cutting speed (8000-9500 rpm), feed rate (0.1-0.25 mm/tooth), depth of cut (0.5-1.5 mm), and tool flute count (two and four flutes) on surface roughness (Ra), material removal rate (MRR), power consumption (Pc), and cutting force (CF). A three-stage hybrid methodology was implemented, in which RSM modelled machinability behaviour and identified significant process parameters, Spherical Fuzzy AHP (SF-AHP) assigned criteria weights under uncertainty, and Fuzzy MARCOS ranked the machining alternatives. Run 1 (9500 rpm, 0.1 mm/tooth, 1.5 mm, four flutes) was identified as the optimal setting, exhibiting lower surface roughness (~ 0.6 μm) and higher MRR (~ 35.6 mm³/min), whereas Run 6 (8750 rpm, 0.175 mm/tooth, 1 mm, two flutes) showed comparatively poorer performance with higher Ra (~ 0.8 μm), reduced MRR (~ 34 mm³/min), and less favorable power consumption and cutting force, indicating weaker overall machinability. Cutting speed and depth of cut strongly influenced Ra and MRR, while feed rate and flute configuration primarily affected Pc and CF. Validation through confirmation experiments, criteria-weight verification, and ranking consistency demonstrated strong agreement between predicted and measured performance. Although limited to a specific silicon-enhanced Ni-SS bimetallic system and finite experimental range, the proposed framework provides a practical and robust strategy for multi-response machinability optimization of WAAM components, offering industrial benefits such as improved surface finish, reduced power consumption, enhanced productivity, and better machining stability. - Source: PubMed
Publication date: 2026/06/12
Sundar Singh Sivam S PKesavan StalinSanthosh A Johnson - Frailty has been shown to predict damage accrual in patients with systemic lupus erythematosus (SLE), including those from Latin America. However, the impact of frailty on mortality has been scarcely evaluated, particularly in Latin American populations. The aim of this study was to evaluate frailty as a predictor of mortality in Latin American SLE patients. - Source: PubMed
Publication date: 2026/06/12
Rashuamán-Conche Benny HaroldGamboa-Cárdenas Rocio VioletaPimentel-Quiroz Victor RománSingh AnubhavReátegui-Sokolova CristinaElera-Fitzcarrald ClaudiaGarcia-Hirsh SamiraPastor-Asurza CesarRodríguez-Bellido ZoilaPerich-Campos Risto AlfredoAlarcón Graciela SUgarte-Gil Manuel Francisco - Enhanced Recovery After Surgery (ERAS) protocols represent a multidisciplinary strategy designed to optimize perioperative management and accelerate postoperative recovery. However, their adoption in vascular surgery-particularly in open aortic procedures-remains limited due to procedural complexity and the large number of elements required for implementation. In other surgical specialties, specific perioperative components have been identified as key determinants of outcome improvement, with adherence rates exceeding 70% considered essential to achieve significant clinical benefits. The aim of this study was to identify the core elements within an ERAS protocol for open aortic surgery that most significantly influence outcomes, and to evaluate the impact of overall protocol adherence on postoperative results. - Source: PubMed
Publication date: 2026/06/12
Campolmi MarcoSpeziali SaraScafa AnnamariaFalso RobertoCasini AndreaBaldini GabrieleDorigo WalterPulli RaffaeleGiacomelli Elena - Among responders to PD-1/PD-L1 blockade, it remains unclear whether tumour type and traditional baseline patient and tumour characteristics provide additional prognostic information for progression risk beyond response depth. - Source: PubMed
Publication date: 2026/06/05
Andersen RikkeJespersen Mette SybergPresti MarioBjornhart BirgitteØstby Anne-CathrineDarras Anne Kirstine MoellerGaritaonaindia YagoRuhlmann Christina HalgaardFrank Malene StøchkelSchmidt HenrikFriis Rasmus BlechingbergGuldbrandt Louise MahnckeHenriksen Jon RøikjærBjerrum AndreasSimonsen Kira SchreinerPalshof Jesper AndreasBorch Troels HolzAndersen Jon LykkegaardKjaer SoerenJensen Niels ViggoAzimi AzizaIversen Ane BundsbaekMeldgaard PeterSteen Sara GrønbechKhan ShawezLuczak Adam AndrzejWahlstrøm StineZitnjak DanielaSvane Inge MarieFristrup NielsKristiansen CharlottePersson Gitte FredbergBastholt LarsPoehl MetteEllebaek EvaDonia Marco