Ask about this productRelated genes to: SULT2B1 Blocking Peptide
- Gene:
- SULT2B1 NIH gene
- Name:
- sulfotransferase family 2B member 1
- Previous symbol:
- -
- Synonyms:
- HSST2
- Chromosome:
- 19q13.3
- Locus Type:
- gene with protein product
- Date approved:
- 1998-08-18
- Date modifiied:
- 2015-11-06
Related products to: SULT2B1 Blocking Peptide
Related articles to: SULT2B1 Blocking Peptide
- Oxidative stress correlates with the development and prognosis of lung adenocarcinoma (LUAD). This study, on the basis of oxidative stress-related genes (OSRGs), commences to identify molecular subtypes and develop prognostic model for LUAD. - Source: PubMed
Publication date: 2026/03/19
Zhang WeiranZhao XiaojiangWang YuhangLi Xin - - Source: PubMed
Publication date: 2026/01/20
Balfour-Lynn Rosie EDhawan Anil - The ocular surface is in direct contact with the external environment and is susceptible to injury from dust, dryness, or other foreign objects. Once corneal injury occurs, a local inflammatory response is triggered, followed by effective repair of the epithelial layer. In this study, we demonstrated that antibiotic treatment delayed corneal wound healing in mice. LC-MS/MS-based untargeted lipidomics and qPCR analyses revealed that the levels of cholesterol sulfate (CS) and the CS-synthesizing enzyme SULT2B1 were significantly upregulated by antibiotic treatment, and SULT2B1 knockout mice exhibited accelerated corneal wound healing along with increased recruitment of neutrophils and eosinophils. Topical application of CS delayed corneal wound healing. In vitro scratch assays revealed that CS delayed the wound healing of human corneal epithelial cells, potentially by inhibiting the DOCK2-Rac pathway. These results highlight the role of commensal bacteria in controlling corneal wound healing via the cholesterol-sulfotransferase pathway. - Source: PubMed
Ogawa MamoruIsobe YosukeUchino HarukiHirayama MasatoshiKato TamotsuNegishi KazunoArita Makoto - Biliary atresia (BA) is a severe neonatal disease characterized by obstruction of the biliary system and hepatic fibrosis. Epithelial-mesenchymal transition (EMT) occurs during the development of liver fibrosis in BA. However, the molecular mechanism that promotes elevated MMP7 expression and mediates the EMT process remains unknown. SULT2B1 has been shown to be involved in the intrahepatocellular EMT process, but its role in BA remains unknown. - Source: PubMed
Publication date: 2025/12/16
Yang TingYang ShenMou WenjunZhao JiaweiWang HuanminChen YajunZhang LiFu LibingWang DingdingHuang Jinshi - Dehydroepiandrosterone (DHEA) is considered an endogenous steroid hormone precursor, and 17-ß estradiol (E2) is one of the estrogen steroid hormones. Of the 13 known human cytosolic sulfotransferases (SULTs), SULT2B1a has been shown to be expressed in steroid hormone-responsive tissues such as the prostate, ovary, and placenta, as well as the fetal brain. Previous studies have demonstrated that SULT2B1a is capable of sulfating 3β-hydroxysteroids such as DHEA and pregnenolone. The present study aimed to investigate the effects of human SULT2B1 single-nucleotide polymorphisms (SNPs) on the enzymatic characteristics of SULT2B1a allozymes in mediating the sulfation of DHEA and E2. - Source: PubMed
Publication date: 2025/11/05
Alatwi EidBairam Ahsan F