Ask about this productRelated genes to: CHIA Blocking Peptide
- Gene:
- CHIA NIH gene
- Name:
- chitinase acidic
- Previous symbol:
- -
- Synonyms:
- AMCase, TSA1902, CHIT2
- Chromosome:
- 1p13.2
- Locus Type:
- gene with protein product
- Date approved:
- 2005-08-16
- Date modifiied:
- 2019-01-21
Related products to: CHIA Blocking Peptide
Related articles to: CHIA Blocking Peptide
- Evidence linking vitamin D deficiency (VDD) to varicose veins remains limited and largely derived from small or cross-sectional studies. We examined whether VDD is associated with incident varicose veins in a large real-world cohort. - Source: PubMed
Publication date: 2026/06/25
Lan Kuo-MaoWang Wei-TingChang Ying-Jen - Medical futility (MF) remains a complex and debated concept in clinical practice, particularly among patients with terminal illness or limited life expectancy, largely due to inconsistencies in its definition and variability in its application, which complicate clinical decision-making. A scoping review was conducted following the methodologies proposed by Arksey, Levac, the Joanna Briggs Institute, and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines to analyze evidence on therapeutic futility in terminally ill adults and the clinical, ethical, and prognostic criteria influencing end-of-life decision-making. A total of 36 published studies were included. Regarding study design, retrospective observational studies predominated (12/36, 33.3%), followed by qualitative studies (9/36, 25.0%), cross-sectional studies (6/36, 16.7%), and, to a lesser extent, prospective or cohort studies (3/36, 8.3%), mixed-methods or case-control studies (2/36, 5.6%), and one case report (1/36, 2.8%). Most studies focused on patients (21/36, 58.3%), primarily in critical care settings or among individuals with advanced disease. A considerable proportion exclusively evaluated healthcare professionals (10/36, 27.8%). Regarding the clinical context, ICUs represented the predominant clinical setting, including general, oncological, surgical, neurological, and medical intensive care units. Other settings included non-critical hospital environments (5/36, 13.9%), oncology-specific settings (3/36, 8.3%), prehospital or emergency care settings (2/36, 5.6%), and additional areas, such as psychiatry, bioethics, or palliative care (3/36, 8.3%). The most frequently identified criterion for MF was the use of treatments without expected clinical benefit (10/36, 27.8%). Ethical and clinical dimensions were addressed across all included studies, with a predominance of multidimensional approaches integrating principles, such as autonomy, beneficence, and justice. Small sample sizes and single-center designs predominated, particularly among qualitative and retrospective studies. MF is a complex and multidimensional concept influenced by clinical, ethical, and sociocultural factors. The heterogeneity in its definition and application complicates the standardization of decision-making, particularly in settings such as ICUs. - Source: PubMed
Publication date: 2026/06/08
Monsalve-Morales GustavoEcheverri-Hoyos JacoboEcheverri Franco Jaime ATuta-Quintero Eduardo - Neuropsychiatric safety concerns, including depression and suicidal ideation, have emerged during the expanding clinical use of incretin-based therapies for type 2 diabetes mellitus (T2DM) and obesity. However, whether risks differ across successive generations of incretin-based therapies remains uncertain. - Source: PubMed
Publication date: 2026/07/08
Chen Solomon Chih-ChengWang Tso-JenChou Chu-KuangLee Chun - The aging population presents both opportunities and challenges. Both global and Malaysian statistics have shown that an increase in longevity is also marked by an increase in the time spent in poor health. A key measure of healthy aging is the ability to lead an independent life. This has implications not only for the individual's quality of life but also for society as a whole; loss of independence with age is associated with increased economic burden and reduced workforce productivity. Understanding and subsequently addressing these age-related declines (slowing or reversing them) is critical in improving the health and societal challenges faced by older adults. However, most studies are focused on Western populations. The scarcity of interventions tailored to multiethnic Asian populations is compounded by the fact that existing measurements rely heavily on Western-designed psychometric instruments, which frequently fail in capturing true cognitive health because of large cultural and educational gaps. - Source: PubMed
Publication date: 2026/07/08
Chia Yook ChinLow Eden Ngah DenJenkins MichaelLee Yun LiSu Tin TinKhairudin RozaineeSalehuddin KhazriyatiVaithilingam SanthaChew JacttyLim Wei LingYong Min HooiSchaefer Alexandre - Combined allergic rhinitis and asthma syndrome (CARAS) is a prevalent chronic respiratory disorder among children, characterized by the coexistence of allergic rhinitis and asthma symptoms, thereby substantially impairing quality of life. Pediatric Tuina, a traditional Chinese manual therapy, has demonstrated potential in the management of pediatric respiratory conditions; however, its effectiveness in treating CARAS remains insufficiently studied. - Source: PubMed
Publication date: 2026/06/23
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