Ask about this productRelated genes to: SLC25A21 Blocking Peptide
- Gene:
- SLC25A21 NIH gene
- Name:
- solute carrier family 25 member 21
- Previous symbol:
- -
- Synonyms:
- ODC1, ODC
- Chromosome:
- 14q13.3
- Locus Type:
- gene with protein product
- Date approved:
- 2001-01-18
- Date modifiied:
- 2016-02-18
Related products to: SLC25A21 Blocking Peptide
Related articles to: SLC25A21 Blocking Peptide
- - Source: PubMed
Publication date: 2026/04/21
Liu WanjunXie WenqingHuang MinghanOu ZhimeiWu MeihuaLv LiLi CaibinLuo QianxinWang QianWu KetongChen Daici - Intracranial aneurysm (IA) is a cerebrovascular disease that lacks effective methods for early diagnosis and risk prediction. Considering the pivotal roles of senescence and inflammation in many diseases, this study aimed to identify related biomarkers for IA and explore their underlying mechanisms. - Source: PubMed
Li XiaoyanLi YingyingZhang LeMao JieLi Bin - Hyperlipidemia complications caused by obesity are a hot issue threatening human health worldwide, and there is an urgent need to explore low-toxicity health foods for intervention. polysaccharides (SFPS) display cholesterol-lowering properties, but the underlying mechanism has not been elucidated. This study investigates the mechanisms by exploring changes in gut microbiota composition, gene expression, and metabolites in mice fed a high-fat diet after intervention with fucoidan (SFF) and SFPS through 16S rRNA sequencing, transcriptomics, and non-targeted metabolomics. The experimental findings indicated that SFPS markedly enhanced the abundance of Akkermansia while concurrently reducing the levels of Actinobacteria, Erysipelotrichaceae, Bifidobacteriaceae, and Peptostreptococcaceae. This was achieved by upregulating the expression of Mt1, Prlr, and slc25a21 and downregulating SREBP-1, thereby inhibiting the cholesterol metabolism pathway. These changes resulted in increased hepatic production and fecal excretion of bile acids and reduced hepatic cholesterol. Our results shed light on the mechanisms behind the cholesterol- and lipid-lowering effects of SFPS, suggesting its potential as a therapeutic agent for hypercholesterolemia. - Source: PubMed
Publication date: 2025/11/11
Su NingHan ShiweiLi ZhengyangLing XiaoyuKong LingqingSong Dafeng - Thrombocytopenia is a common adverse side effects of Linezolid (LZD) but the underlying mechanism remains unclear. This study aimed to analyze the mechanism of LZD induced thrombocytopenia for LZD induced thrombocytopenia. - Source: PubMed
Publication date: 2025/09/22
Yang YaWang NingXiong LirongFu PeishuTian YanpingLuo ShenglinSun FengjunXia Peiyuan - This study investigated the genetic basis of teat number variation in Dongliao black pigs. A total of 765 pigs were genotyped using the Porcine 50K SNP chip, and their teat numbers were recorded. Heritability estimates for total teat number (TTN) and teat pair number (TPN) were 0.091 and 0.097, respectively. Genome-wide association studies identified 74 significant SNPs for TTN and 105 for TPN. Nine candidate genes related to the teat number were identified: and . These findings provide insights into the genetic architecture of teat number variation in Dongliao black pigs. - Source: PubMed
Publication date: 2025/05/14
Ke JuanChen ChangyiFei JunwenLuo KeCheng YuYu HuiminCheng ChaoYan YiqingZhang XiaoranLiang ShuangSun HaoBai ChunyanSun Boxing