Ask about this productRelated genes to: ST6GALNAC3 Blocking Peptide
- Gene:
- ST6GALNAC3 NIH gene
- Name:
- ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
- Previous symbol:
- SIAT7C
- Synonyms:
- -
- Chromosome:
- 1p31.1
- Locus Type:
- gene with protein product
- Date approved:
- 2003-12-05
- Date modifiied:
- 2016-04-29
Related products to: ST6GALNAC3 Blocking Peptide
Related articles to: ST6GALNAC3 Blocking Peptide
- Dermal papilla is developed from the continuous proliferation and differentiation of dermal fibroblasts, which is the key to the normal development of hair follicles. This study aims to elucidate the role of lncRNA ST6GALNAC3, which is significantly differentially expressed during the secondary hair follicle development stage in cashmere goats, on dermal fibroblasts, and to analyze the regulatory mechanism of this lncRNA thoroughly. - Source: PubMed
Publication date: 2025/06/24
Ma RongMa QingZhang LuMa BingjieBao XuxuZhang YimingWang LeLv QiWang ZhiyingWang RuijunSu RuiZhao YanhongShang FangzhengWang YuZhang Yanjun - Two subgroups with high expression of B7-H1 and low expression of B7-H1 were successfully isolated from primitive human umbilical cord mesenchymal stem cells. And exosomes with high B7-H1 expression and low B7-H1 expression were successfully isolated. In comparison to the sham-operated group, mice in the IRI group demonstrated elevated serum levels of blood urea nitrogen (BUN) and serum creatinine (Scr), accompanied by a more pronounced degree of renal tissue damage. The administration of exosomes via the tail vein markedly accelerated the recovery of renal function in IRI mice, with the therapeutic effect beingmore pronounced in those treated with B7-H1high-Exo. Moreover RNA sequencing of mouse kidney treated with B7-H1high-Exo and B7-H1low-Exo showed that eight genes (C3, IRF7, AREG, CXCL10, Aldh1l2, Fnip2, Vcam1, St6galnac3) were involved in the pathophysiological process of ischemia-reperfusion injury. The and experiments showed that the expression level of C3 protein was significantly decreased, which indicated that B7-H1high-Exo played a therapeutic role by down-regulating C3. - Source: PubMed
Publication date: 2025/04/02
He JiahuiYao YaweiWang RuiyanLiu YujiaWan XingyuWang HaoZhou YuqiangWang WenjingMa YanLv Xinghua - Bladder urothelial carcinoma (BLCA) is a highly heterogeneous cancer with a wide range of prognoses, ranging from low-grade non-muscle-invasive bladder cancer (NMIBC), which has a good prognosis but a high recurrence rate, to high-grade muscle-invasive bladder cancer (MIBC), which has a poor prognosis. Glycosylation dysregulation plays a significant role in cancer development. Therefore, this study aimed to investigate the role of glycosyltransferases (GT)-related genes in the prognosis of BLCA and to develop a prognostic model based on these genes to predict overall survival (OS) and assess its clinical application. - Source: PubMed
Publication date: 2024/12/28
Li WeipingZuo KangweiZhao QiGuo ChenhaoLiu ZirongLiu ChengJing Suoshi - Ovarian and other peritoneal cancers have a strong tendency to metastasize into the surrounding adipose tissue. This study describes an effect of the adipose microenvironment on upregulation of sialic acid-containing glycans in ovarian cancer (OC). Heterogeneous populations of glycosylated OC tumors converged to a highly sialylated cell state that regulates tumorigenesis in an immune-dependent manner. - Source: PubMed
Publication date: 2024/07/22
Fox AlexandraLeonard Garry DAdzibolosu NicholasWong TerrenceTedja RoslynSharma SapnaGogoi RadhikaMorris RobertMor GilFehl CharlieAlvero Ayesha B - Eukaryotic elongation factor 1A1 (eEF1A1) is an RNA-binding protein that is associated with PARK2 activity in cells, suggesting a possible role in Parkinson's disease (PD). - Source: PubMed
Publication date: 2024/05/22
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