Ask about this productRelated genes to: ADAM33 Blocking Peptide
- Gene:
- ADAM33 NIH gene
- Name:
- ADAM metallopeptidase domain 33
- Previous symbol:
- C20orf153
- Synonyms:
- DKFZp434K0521, dJ964F7.1
- Chromosome:
- 20p13
- Locus Type:
- gene with protein product
- Date approved:
- 2001-04-10
- Date modifiied:
- 2015-08-26
Related products to: ADAM33 Blocking Peptide
Related articles to: ADAM33 Blocking Peptide
- Severe cases of COVID-19 can result in acute respiratory distress syndrome, extensive lung damage, and long-term structural changes, particularly extracellular matrix (ECM) remodeling. ECM remodeling is characterized by excessive collagen deposition and imbalanced activity of enzymes, such as matrix metalloproteinases. Although immune and inflammatory pathways in patients with COVID-19 are well understood, the epigenetic and post-transcriptional regulation is not well understood. In this exploratory study, we examined DNA methylation and miRNA-mediated regulation in lung tissues from fatal cases of COVID-19. - Source: PubMed
Publication date: 2026/05/07
Cardoso Gabriela Casanida Cunha Regiane StafimMiniskiskosky GuilhermeMachado-Souza Cleberde Noronha Luciade Paula Caroline Busatta VazTuon Felipe Franciscode Souza Ramos Cavalieri Edneia Amancio - Atopic dermatitis (AD) is a clinically heterogeneous immune-mediated skin disorder. The lack of reliable clinical stratification tools and predictive biomarkers for therapeutic response remains a critical unmet need to optimize treatment and advance precision dermatology. - Source: PubMed
Publication date: 2026/04/10
Morelli MartinaScaglione Giovanni LucaDattolo AnnaGalluzzo MarcoScarponi ClaudiaMoretta GaiaProvini AlessiaRusso FilomenaCocuroccia BarbaraSordi DonatellaTalamonti MarinaVillella ValeriaSelvi Fabio RomanoMercurio LauraPaganini ClaudiaMortato EdoardoBianchi LucaDe Pità OrnellaPallotta SabatinoScala EnricoAlbanesi CristinaMadonna Stefania - To explore the potential association between five single nucleotide polymorphisms (SNPs) (rs44707, rs612709, rs598418, rs2280089, and rs574174) in the ADAM33 gene and asthma susceptibility in the Zhuang population of Guangxi, China. - Source: PubMed
Publication date: 2026/03/21
Qin Zan-MeiHuang Xue-MeiWei XuanHe Zhi-YiDeng Jing-Min - The phenotypic nature of multimorbidity in severe asthma is poorly understood. Our aims in this study were to define multimorbidity phenotypes and their characteristics in severe asthma across Europe by identifying and characterising co-aggregation of comorbidities. - Source: PubMed
Publication date: 2026/02/05
Freeman AnnaRink SašaBansal Aruna TFrankemölle BettySingh MeharSont Jacob KBossios ApostolosAinsworth BenHyland MichaelChaudhuri RekhaMatisa DaceMihaltan FlorinSpanevello AntonioHeffler EnricoAdcock IanZappa MartinaCanonica Giorgio WalterBrusselle GuyBourdin ArnaudMaria Luigia Costanzo Giulia AnnaHorvath IldikoLúðvíksdóttir DóraPrincipe StefaniaKopač PeterLoureiro Cláudia ChavesSiddiqui SalmanEgesten ArneKalinauskaite-Zukauske VirginijaDimic-Janjic SanjaRoberts GrahamHromis SanjaMilenkovic BranislavaVarkonyi-Sepp JuditGoksel OzlemPereira Ana MDjukanovic RatkoRizzi AngelaCaminati MarcoHou RuihuaŠtajduhar AnamarijaParóczai DóraBrussino LuisaHeaney LiamHaitchi Hans MichaelBonini MatteoBieksiene KristinaDamadoglu EbruYasinska ValentynaGemicioglu BilunGrle Sanja PopovićBrinke Anneke TenCsoma ZsuzsannaKroica IvetaKuna PiotrDahlen BarbroPorsbjerg CelesteHodge HilaryŠkrgat SabinaSchleich FlorenceKurukulaaratchy Ramesh J - The Body Mass Index (BMI), integrating body weight and length, is a widely used metric for obesity assessment in humans. As pigs serve as crucial biomedical models, the application of BMI in swine and its genetic basis remain poorly explored. This study aimed to investigate the genetic architecture of pig BMI and compare two carcass-based BMI metrics (BMI-S and BMI-O) for breeding applicability. A total of 439 Landrace × Yorkshire crossbred pigs were genotyped with a 50 K SNP chip; heritability was estimated via a mixed linear model, and genome-wide association study (GWAS) was performed using the BLINK model. BMI-S and BMI-O exhibited moderate-to-high heritability of 0.55 and 0.47, respectively, with 17 genome-wide significant SNPs detected-including the top associated SNP on chromosome 4 and on chromosome 7. Key candidate genes (, , , ) and 5 SNP-trait associations validated in PigQTLdb were linked to lipid/energy metabolism and muscle development. Carcass-based BMI improved phenotypic accuracy, and our findings provide core genetic markers and a theoretical basis for molecular breeding of pig body conformation and lipid deposition traits. - Source: PubMed
Publication date: 2026/01/14
Jin LongBai ChunyanChen JinghanFeng ChengyueDong FengyiZhang XiaoranFei JunwenHe YuLiu WuyangChen ChangyiSun BoxingWang DaliSun Hao