Ask about this productRelated genes to: SLC39A2 Blocking Peptide
- Gene:
- SLC39A2 NIH gene
- Name:
- solute carrier family 39 member 2
- Previous symbol:
- -
- Synonyms:
- ZIP2
- Chromosome:
- 14q11.2
- Locus Type:
- gene with protein product
- Date approved:
- 2002-02-12
- Date modifiied:
- 2016-10-05
Related products to: SLC39A2 Blocking Peptide
Related articles to: SLC39A2 Blocking Peptide
- Eosinophilic esophagitis (EoE) and its related subtypes-such as EoE-like esophagitis, lymphocytic esophagitis, and nonspecific esophagitis-pose significant diagnostic challenges due to overlapping clinical, histological, and endoscopic features. Although conventional EoE is well-characterized as a Th2-mediated disorder, the molecular and immunological drivers for its subtypes are poorly understood. We aimed to elucidate the unique molecular signatures underlying these esophageal inflammatory conditions, with the goal of refining disease classification and paving way to targeted therapeutic approaches. - Source: PubMed
Publication date: 2026/03/12
Twum EricBaranova AnchaUllah Aman - Allergic asthma pathogenesis encompasses systemic immune, metabolic, and epithelial barrier dysfunction; however, minimally invasive tools to longitudinally explore these processes remain limited. - Source: PubMed
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Liu DanielKim MadelineDel Duca EsterBar JonathanLau MeganLargen JosephAgache IoanaGuttman-Yassky Emma - Reproductive traits of cattle, especially the Nelore breed, have notable importance in the global economy and are recognized throughout the beef cattle production system. Therefore, we aimed to identify regulatory networks of transcription factors (TFs) and the most promising candidate genes for scrotal circumference (SC), testicular hypoplasia (HT), and sexual precocity (SP) that were previously identified in GWAS analysis. We identified 444 genes from a peer-reviewed systematic review related to male reproductive traits. Biological processes were then identified using DAVID 6.8, and a regulatory network of TFs was constructed. Enriched biological processes and seven candidate genes (BICC1, CDH1, FOXG1, GHR, OR52E4, SLC17A7, and ITGA2) were identified, which were associated with some biological processes linked to reproduction. Furthermore, gene-TF networks were obtained from TFs (GABPA, HNF1A, HNF4A, PAX2, and TFAP2A) associated with bovine reproduction, and the 22 most promising candidate genes (CDKN2C, CLPTM1L, GCSAM, GPR12, GTF3A, HSPBAP1, IL32, ILDR1, LOC100141258, LOC100336282, LOC107131530, LOC112449111, LOC618541, LOC781785, MIX23, MTIF3, PARP9, PCED1B, RNASE2, SLC39A2, SPA17 and TMEM253) were found to be specifically linked to sexual precocity. The identified candidate genes and transcription factors have significant potential to influence the evaluated traits in Nelore bulls. Future research and applications of these genetic factors may improve the breeding and enhancement of Nelore cattle. - Source: PubMed
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