Ask about this productRelated genes to: HSPH1 Blocking Peptide
- Gene:
- HSPH1 NIH gene
- Name:
- heat shock protein family H (Hsp110) member 1
- Previous symbol:
- -
- Synonyms:
- HSP105B, KIAA0201, HSP105A, NY-CO-25
- Chromosome:
- 13q12.3
- Locus Type:
- gene with protein product
- Date approved:
- 2003-02-19
- Date modifiied:
- 2015-11-19
Related products to: HSPH1 Blocking Peptide
Related articles to: HSPH1 Blocking Peptide
- Esophageal adenocarcinoma (EAC) is a highly aggressive malignancy with poor prognosis, often evolving from Barrett's esophagus (BE). Understanding the molecular mechanisms driving this progression is critical for identifying diagnostic biomarkers and therapeutic targets. - Source: PubMed
Publication date: 2026/05/10
Tao LulongGuo YantingLu FangQi ChangyongZhang GuoxinYan Jin - -Aminobutyric acid (GABA) is the principal inhibitory neurotransmitter in the central nervous system and is involved in the development of neural tissue as well as the regulation of its functions. Meanwhile, GABA has also been demonstrated to confer multiple physiological benefits, including alleviating stress and improving metabolic homeostasis. This study investigated GABA effects on proliferation, differentiation, and temperature stress protection of bovine skeletal muscle satellite cells (BSCs). - Source: PubMed
Publication date: 2026/04/14
Manzoor AbidNaseem SajidaFu ZhiqiRuan ChaohuiLiu XuYan ChunriChoi SeonghoLi Xiangzi - This study investigates how heat shock protein Hsph1 regulates endoplasmic reticulum stress (ERS) in myocardial ischemia-reperfusion injury (MIRI), aiming to identify new targets for MIRI intervention. - Source: PubMed
Lei YingChen YiPan Yibin - The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. - Source: PubMed
Publication date: 2026/03/07
Dąbrowska IzabelaGrzędzicka-Agko JowitaKiełbik PaulaTrela MichałWitkowska-Piłaszewicz Olga - The indigenous Afrikaner and composite Bonsmara cattle breeds are hardy and adapted to the diverse South African climate and biomes. Both breeds have been successfully used in the South African stud and commercial industries. This study explored the genomic diversity and population structure, as well as identified selection signatures within and between the Afrikaner and Bonsmara breeds with a focus on signatures related to adaptation traits. Short-read whole genome sequencing data of 42 Afrikaner and 43 Bonsmara cattle were analysed. Diversity analysis revealed comparable nucleotide diversity levels in the Afrikaner and Bonsmara populations, with the Bonsmara having weaker average linkage disequilibrium between adjacent single nucleotide polymorphisms as well as having fewer runs of homozygosity. Furthermore, genetic structure analysis revealed distinct clustering of both populations, with the exception of a subset of Afrikaner individuals having been infused with Bonsmara genetics. Between and within breed selection signatures were detected using the fixation index and integrated haplotype score approaches, respectively. Several gene ontology terms were described based on the detected selection signatures, with the most significant being nervous system development and multicellular organismal processes. Finally, functional annotation of the candidate genes from the within-breed selection signature analysis revealed several genes (, , , ) relating to adaptive traits in both populations. The location of the within and between breed selection signatures in this study population is consistent with the performance and adaptive characteristics of both breeds and may enhance future breeding strategies with the inclusion of these breeds in crossbreeding programs. Furthermore, a comprehensive genomic characterization of these breeds through whole genome sequencing data is important as these adapted breeds are valuable reservoirs of genetic variation. - Source: PubMed
Publication date: 2026/02/17
Alberts Dvan Marle-Köster EJoubert FBerry D P