Ask about this productRelated genes to: LDLRAD1 Blocking Peptide
- Gene:
- LDLRAD1 NIH gene
- Name:
- low density lipoprotein receptor class A domain containing 1
- Previous symbol:
- -
- Synonyms:
- -
- Chromosome:
- 1p32.3
- Locus Type:
- gene with protein product
- Date approved:
- 2005-07-14
- Date modifiied:
- 2015-09-03
Related products to: LDLRAD1 Blocking Peptide
Related articles to: LDLRAD1 Blocking Peptide
- Esophageal cancer is increasingly recognized as a significant global malignancy. The main pathological subtype of this cancer is esophageal squamous cell carcinoma (ESCC), which displays a higher degree of malignancy and a poorer prognosis. Reactive oxygen species (ROS) play a critical role in modulating the immune response to tumors, and understanding the regulation of ROS in ESCC could lead to novel and improved therapeutic strategies for ESCC patients. - Source: PubMed
Publication date: 2024/07/29
Lu QiangYang QiZhao JinboLi GuizhenZhang JiPengJia ChenghuiWan YiChen Yan - Genome-wide association studies (GWAS) have identified genetic variants linked to fat metabolism and related traits, but rarely pinpoint causative variants. This limitation arises from GWAS not considering functional implications of noncoding variants that can affect transcription factor binding and potentially regulate gene expression. The aim of this study is to investigate a candidate noncoding functional variant within a genetic locus flagged by a GWAS SNP associated with non-alcoholic fatty liver disease (NAFLD), a condition characterized by liver fat accumulation in non-alcohol consumers. - Source: PubMed
Publication date: 2024/02/16
Castillejo-López CasimiroBárcenas-Walls José RamónCavalli MarcoLarsson AndersWadelius Claes - Alpaca (Vicugna pacos), llama (Lama glama), vicugna (Vicugna vicugna) and guanaco (Lama guanicoe), are the camelid species distributed over the Andean high-altitude grasslands, the Altiplano, and the Patagonian arid steppes. Despite the wide interest on these animals, most of the loci under selection are still unknown. Using whole-genome sequencing (WGS) data we investigated the occurrence and the distribution of Runs Of Homozygosity (ROHs) across the South American Camelids (SACs) genome to identify the genetic relationship between the four species and the potential signatures of selection. - Source: PubMed
Publication date: 2023/08/21
Pallotti StefanoPicciolini MatteoAntonini MarcoRenieri CarloNapolioni Valerio - Genome-wide association studies have identified multiple genomic loci associated with coronary artery disease, but most are common variants in non-coding regions that provide limited information on causal genes and etiology of the disease. To overcome the limited scope that common variants provide, we focused our investigation on low-frequency and rare sequence variations primarily residing in coding regions of the genome. - Source: PubMed
Publication date: 2020/11/13
Hahn JulieFu Yi-PingBrown Michael RBis Joshua Cde Vries Paul SFeitosa Mary FYanek Lisa RWeiss StefanGiulianini FrancoSmith Albert VernonGuo XiuqingBartz Traci MBecker Diane MBecker Lewis CBoerwinkle EricBrody Jennifer AChen Yii-Der IdaFranco Oscar HGrove MeganHarris Tamara BHofman AlbertHwang Shih-JenKral Brian GLauner Lenore JMarkus Marcello R PRice Kenneth MRich Stephen SRidker Paul MRivadeneira FernandoRotter Jerome ISotoodehnia NonaTaylor Kent DUitterlinden André GVölker UweVölzke HenryYao JieChasman Daniel IDörr MarcusGudnason VilmundurMathias Rasika APost WendyPsaty Bruce MDehghan AbbasO'Donnell Christopher JMorrison Alanna C - Dysfunction of the bronchial epithelium plays an important role in asthma; however, its measurement is challenging. Columnar epithelial cells are often quantified, yet rarely analysed, in induced sputum studies. - Source: PubMed
Publication date: 2019/08/06
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