Ask about this productRelated genes to: ABCG5 Blocking Peptide
- Gene:
- ABCG5 NIH gene
- Name:
- ATP binding cassette subfamily G member 5
- Previous symbol:
- -
- Synonyms:
- STSL
- Chromosome:
- 2p21
- Locus Type:
- gene with protein product
- Date approved:
- 2000-12-12
- Date modifiied:
- 2019-04-23
Related products to: ABCG5 Blocking Peptide
Related articles to: ABCG5 Blocking Peptide
- This study aimed to assess the impact of dietary taurine supplementation on egg quality, polyunsaturated fatty acids, and cholesterol contents in egg during the late laying period in hens. - Source: PubMed
Publication date: 2026/03/12
Wang ShunyangZhang QiqiLu HuiminYu MengAlagawany Mahoud MChen ChengZhou Zhongxin - Current treatments for ulcerative colitis (UC) are limited by insufficient efficacy and potential side effects. This study aimed to investigate the prophylactic efficacy of (L.) Moench flower polysaccharide extract (APE) against dextran sulfate sodium (DSS)-induced UC in mice. APE substantially ameliorated DSS-induced UC symptoms, intestinal barrier disruption, and concurrent microbiota dysbiosis with associated metabolite shifts. Gut microbiota depletion using antibiotic treatment removed the alleviative effect of APE against UC. Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses of gut microbiota and metabolomic data highlighted the role of ABC transporters in the ameliorative effect of APE against UC. The expression of colonic ABC transporter-associated proteins Abcg5 and Abcg8 was significantly upregulated by APE at both mRNA and protein levels, which was abolished under antibiotic treatment. These findings highlight the potential of APE as an effective prebiotic for UC prevention and a valuable functional food ingredient for dietary interventions. - Source: PubMed
Publication date: 2026/03/18
Deng YuanleZhao ZiqiaoGu XiangfuWang LiqunZhang YujieHuang XiaoyiLi XingjieLei XudanXiong ZhujuanZhang FushengZhu Yongxia - - Source: PubMed
Publication date: 2026/03/13
Zang QifengCheng LuZang Yinshan - Sitosterolemia is a rare autosomal recessive lipid disorder caused by mutations in the ABCG5 or ABCG8 genes, resulting in excessive intestinal absorption and impaired biliary excretion of plant sterols, which leads to their accumulation in plasma and tissues. Clinical manifestations include premature coronary artery disease, liver dysfunction, hepatosplenomegaly, and hematologic abnormalities. - Source: PubMed
Publication date: 2026/02/19
Waluś-Miarka MałgorzataNogieć AnnaFedak AndrzejMalone CaitlinKhalil YoussefClayton Peter TChyrchel BernadetaMałecki Maciej THumphries Steve E - Angiopoietin-like protein 3 (Angptl3), a factor secreted by the liver, inhibits lipoprotein lipase and other lipases by forming a complex with Angptl4 and 8. However, whether inhibition of Angptl3 can alleviate hepatic lipid accumulation and atherosclerosis remains unclear. Therefore, this study explored the effect of small interfering RNA (siRNA)-based inactivation of Angptl3 on metabolic dysfunction-associated fatty liver disease (MAFLD) and atherosclerosis in male LDLR-deficient hamsters. - Source: PubMed
Publication date: 2026/03/05
Zhang XiaohongHan YufeiZheng LiwenHe XiaokuiPu YungangWei LiliWang YuhuiXian Xunde