Ask about this productRelated genes to: Gfap antibody
- Gene:
- GFAP NIH gene
- Name:
- glial fibrillary acidic protein
- Previous symbol:
- -
- Synonyms:
- FLJ45472
- Chromosome:
- 17q21.31
- Locus Type:
- gene with protein product
- Date approved:
- 1989-12-07
- Date modifiied:
- 2016-10-05
Related products to: Gfap antibody
Related articles to: Gfap antibody
- Neural autoantibody testing is standard for patients with suspected autoimmune neurologic disorders. The number of neural antibodies has increased dramatically in the past 40 years, with over 50 disease-specific neural antibodies defined to date. The advent of immune-profiling assays such as protein array and phage immunoprecipitation sequencing (PhIP-Seq) has further expedited the rate of antibody discovery, with many recent targets identified using these methods. In this review, we discuss traditional and novel methods of antibody discovery, with an emphasis on the incorporation of protein array and PhIP-Seq into our antibody discovery approach. Advantages, limitations, and potential future uses of these platforms within the field of autoimmune neurology are also considered. - Source: PubMed
Publication date: 2026/05/18
Gilligan MichaelMcKeon Andrew - Prox-1 (prospero homeobox protein 1) is a master control gene for lymphatic vessel development and it has been widely used as a marker to detect lymphatic vessels inside and outside the eye. We herein report a novel finding of Prox-1 expression on the astrocytes of the optic nerve, a critical structure that conveys visual information from the retina to the brain. We identified that Prox-1 expressing cells were widely distributed inside the optic nerve. These cells co-expressed both GFAP (glial fibrillary acidic protein) and AQP4 (aquaporin-4) which are typical markers for astrocytes. Interestingly, some of the Prox-1+ cells ensheath CD31+ blood vessels inside the optic nerve and these cells are part of the glymphatic system utilized for ocular fluid circulation. This study not only reveals a novel expression pattern of Prox-1 in the optic nerve but also identifies a new marker for the glymphatic system in this critical structure. Further exploration on this novel phenomenon may re-veal new mechanisms and therapeutic targets for optic nerve-related diseases that affect many patients worldwide. - Source: PubMed
Yang YZhang L WZhang L LLi GChen L - Trimethyltin (TMT) is an organotin compound known to induce neurotoxicity within the limbic system of the brain, particularly in the hippocampal region, with neurodegenerative changes resembling those of Alzheimer's disease (AD). - Source: PubMed
Publication date: 2026/04/25
Khosh Ravesh RoyaKhodashenas VahidGoudarzi MinaMohammadi LeilaBaluchnejadmojarad TourandokhtRoghani Mehrdad - Germinal matrix hemorrhage (GMH) is a major cause of mortality and neurodevelopmental disability in very preterm infants (<32 gestation weeks). This study evaluated lithium's neuroprotective effects in a neonatal rat model of GMH. - Source: PubMed
Publication date: 2026/05/13
Yuan JingZhang XiaoliYang YuZhang JieJing XiaoxiaoXu YiranHe TiantianZhu JinjinWu YananDong HuifangWang XiaoyangZhu Changlian - We investigated the relationship between metabotropic glutamate receptor subtype 5 (mGluR5) availability and plasma biomarkers in individuals with cognitive impairment. - Source: PubMed
Hu TangyueWang YanWang JieMao XiaoxieRen ShuhuaHe KunGuan YihuiHuang QiLi BinyinXie Fang