Ask about this productRelated genes to: C2orf60 antibody
- Gene:
- TYW5 NIH gene
- Name:
- tRNA-yW synthesizing protein 5
- Previous symbol:
- C2orf60
- Synonyms:
- FLJ37953
- Chromosome:
- 2q33.1
- Locus Type:
- gene with protein product
- Date approved:
- 2007-07-10
- Date modifiied:
- 2014-11-18
Related products to: C2orf60 antibody
Related articles to: C2orf60 antibody
- Puberty onset signifies the beginning of sexual maturation and reproductive phase in poultry indeed, and plays an essential role in genetics and breeding. Studying gonadal development is one of the important approaches to exploring the genetic mechanism of puberty onset. - Source: PubMed
Publication date: 2024/11/29
Xu MengruTang QianQi JingjingHan XuTao QiuyuLu YinjuanBai YuanHu ShenqiangLi LiangBai LiliHu JiweiWang JiwenLiu Hehe - Animal domestication, climate changes over time, and artificial selection have played significant roles in shaping the genome structure of various animal species, including cattle. These processes have led to the emergence of several indigenous cattle breeds with distinct genetic characteristics. This study focused on unraveling the genetic diversity and identifying candidate genomic regions in eight indigenous cattle breeds of Iran. The data consisted of ∼777 962 single nucleotide polymorphisms (SNPs) of 89 animals from Iranian indigenous cattle scattered throughout the country. We employed various methods, including integrated haplotype score, , and cross-population composite likelihood ratio, to conduct a genome scan for detecting selection signals within and between cattle populations. Average observed heterozygosity across the populations was 0.36, with a range of 0.32-0.40. In addition, negative and low rates of inbreeding (FIS) in the populations were observed. The genome-wide analysis revealed several genomic regions that harbored candidate genes associated with production traits (e.g., MFSD1, TYW5, ADRB2, BLK, and CRTC3), adaptation to local environmental constraints (CACNA2D1, CXCL3, and GRO1), and coat color (DYM). Finally, the study of the reported quantitative trait loci (QTL) regions in the cattle genome demonstrated that the identified regions were associated with QTL related to important traits such as milk composition, body weight, daily gain, feed conversion, and residual feed intake. Overall, this study contributes to a better understanding of the genetic diversity and potential candidate genes underlying important traits in Iranian indigenous cattle breeds, which can inform future breeding and conservation efforts. - Source: PubMed
Publication date: 2023/11/14
Ameri Nader ForoughMoradian HasanKoshkoiyeh Ali EsmailizadehMontazeri MahdiyehMadabi Elaheh RostamzadehFozi Masood Asadi - To identify risk genes whose expression are regulated by the reported risk variants and to explore the potential regulatory mechanism in schizophrenia (SCZ). - Source: PubMed
Publication date: 2023/04/24
Zhang ChengchengLi XiaojingZhao LianshengGuo WanjunDeng WeiWang QiangHu XunDu XiangdongSham Pak ChungLuo XiongjianLi Tao - Important sex differences exist in tau pathology along the Alzheimer disease (AD) continuum, with women showing enhanced tau deposition compared with men, especially during the mild cognitive impairment (MCI) phase. This study aims to identify specific genetic variants associated with sex differences in regional tau aggregation, as measured with PET. - Source: PubMed
Publication date: 2022/12/08
Wang XinBroce IrisDeters Kacie DFan Chun ChiehBanks Sarah Jane - Identifying the causal genes at the risk loci and elucidating their roles in schizophrenia (SCZ) pathogenesis remain significant challenges. To explore risk variants associated with gene expression in the human brain and to identify genes whose expression change may contribute to the susceptibility of SCZ, here we report a comprehensive integrative study on SCZ. - Source: PubMed
Publication date: 2022/05/09
Zhang ChengchengLi XiaojingZhao LianshengLiang RongDeng WeiGuo WanjunWang QiangHu XunDu XiangdongSham Pak ChungLuo XiongjianLi Tao