Ask about this productRelated genes to: HELT antibody
- Gene:
- HELT NIH gene
- Name:
- helt bHLH transcription factor
- Previous symbol:
- -
- Synonyms:
- HESL, HCM1228, Mgn, bHLHb44, MEGANE
- Chromosome:
- 4q35.1
- Locus Type:
- gene with protein product
- Date approved:
- 2008-04-21
- Date modifiied:
- 2014-11-19
Related products to: HELT antibody
Related articles to: HELT antibody
- Inappropriate antibiotic use in the community is a primary driver of antimicrobial resistance (AMR), particularly in low- and middle-income countries (LMICs) where ambulatory care, including primary healthcare (PHC) facilities, is the main point of contact. While stewardship efforts in South Africa have focused largely on prescribers and hospitals, the behavioral drivers of community antimicrobial use, specifically the , remain poorly understood. This study aimed to address this gap by applying the newly developed Community Antimicrobial Use Scale (CAMUS) to quantify the prevalence of misuse and identify potential independent sociodemographic and behavioral factors associated with inappropriate antibiotic use among ambulatory care patients in South Africa. - Source: PubMed
Publication date: 2026/03/20
Ramdas NishanaSchellack NatalieUys CorrieGodman BrianCampbell Stephen MMeyer Johanna C - : Liver function is difficult to estimate accurately. Conventional liver function tests can be normal, even in severe diseases. Dynamic liver function tests, including indocyanine green (ICG) clearance and hepatobiliary scintigraphy (HBS), are useful in adults. We aimed to evaluate the association between ICG clearance and HBS in children with liver disease and to identify liver disease markers associated with liver function measured with ICG clearance and HBS. : Children aged 0-18 years followed at Copenhagen University Hospital, Rigshospitalet between November 2015 and August 2024 were eligible for inclusion if they had acute or chronic liver disease, suspected liver disease, or previous liver transplantation (LTx). All underwent ICG clearance and HBS. : We included 131 children with a total of 200 visits. The median visit age was 11.4 [6.6; 15.6] years. The ICG-plasma disappearance rate had the strongest correlation with the hepatic extraction fraction (ρ = 0.64, < 0.001). ICG clearance and HBS were associated with liver injury, reduced synthetic function, cholestasis, cirrhosis, and portal hypertension, while only ICG clearance was associated with the portal blood flow. LTx was associated with increased HBS parameters, but not with ICG clearance. : ICG clearance and HBS are correlated, and both are associated with most conventional liver function markers. This suggests their usefulness in evaluating children with liver disease. However, further evaluation of the predictive and clinical value of ICG clearance and HBS in disease progression is needed. - Source: PubMed
Publication date: 2026/03/09
Helt Thora WesenbergNielsen JonFicerai-Garland Gabriellade Nijs RobinWinther Christina LouiseMøller SørenSetterberg ViktoriaChristensen Vibeke BrixBorgwardt Lise - To relate post-surgical feeding regimens to growth and surgical outcomes in children with biliary atresia (BA) after hepato-portoenterostomy (Kasai). - Source: PubMed
Publication date: 2026/02/23
Helt Thora Wesenbergde Kleine Ruben HJohansen Lars SøndergaardDijkstra TietieHulscher Jan B FVerkade Henkjan JChristensen Vibeke Brix - The HELT-ES score is a new risk assessment tool for ischemic stroke in Japanese patients with atrial fibrillation (AF), so we investigated its association with clinical outcomes after catheter ablation (CA) for AF. - Source: PubMed
Publication date: 2025/12/20
Tanaka KiuOkada AyakoMinamisawa MasatoshiKomatsu ToshinoriKobayashi HidekiOkano TakahiroOguchi YasutakaTabata HiroakiShoin WataruNohno YasumasaUsui TatsuyaTakeuchi TakahiroHirabayashi MasaoKatagiri YuichiKasai ToshioKozu RyosukeWakabayashi YasushiUeki YasushiYoshie KojiKato TamonSaigusa TatsuyaEbisawa SoichiroKuwahara Koichiro - Papua New Guinea (PNG) faces a critical food security crisis, with nearly half of children under five experiencing stunting-more than twice the global average. Combined with high rates of wasting and overweight, this reflects the country's 'double burden of malnutrition'. Furthermore, public health and environmental pressures in PNG are intensifying, particularly as climate change reduces crop yields, nutrient density and ecosystem stability. Addressing these interconnected challenges demands integrated strategies that strengthen both food and soil security. This article applies the One Health framework to PNG's social-ecological system by examining two interventions: soil health restoration and mangrove ecosystem rehabilitation. These interventions enhance landscape resilience, restore degraded soils and sustain protein-rich food sources. Our novel PNG One Health () framework-a culturally grounded approach-emphasises strong soil, strong food and strong community (), with family, community-based approaches and gender equity as cornerstones for sustainable development. - Source: PubMed
Publication date: 2026/01/29
Swan TomMaora Josephine SaulPamphilon BarbaraField Damien