Ask about this productRelated genes to: ZNF572 antibody
- Gene:
- ZNF572 NIH gene
- Name:
- zinc finger protein 572
- Previous symbol:
- -
- Synonyms:
- FLJ38002
- Chromosome:
- 8q24.13
- Locus Type:
- gene with protein product
- Date approved:
- 2004-02-15
- Date modifiied:
- 2014-11-18
Related products to: ZNF572 antibody
Related articles to: ZNF572 antibody
- Genome-wide association studies (GWAS) of postpartum depression (PPD) based on accumulated cohorts with multiple ethnic backgrounds have failed to identify significantly associated loci. Herein, we conducted a GWAS of Japanese perinatal women along with detailed confounding information to uncover PPD-associated loci. - Source: PubMed
Publication date: 2024/09/17
Li XueTakahashi NagahideNarita AkiraNakamura YukakoSakurai-Yageta MikaMurakami KeikoIshikuro MamiObara TakuKikuya MasahiroUeno FumihikoMetoki HirohitoOhseto HisashiTakahashi IppeiNakamura TomohiroWarita NorikoShoji TomokaYu ZhiqianOno ChiakiKobayashi NatsukoKikuchi SayaMatsuki TasukuNagami FujiOgishima SoichiSugawara JunichiHoshiai TetsuroSaito MasatoshiFuse NobuoKinoshita KengoYamamoto MasayukiYaegashi NobuoOzaki NorioTamiya GenKuriyama ShinichiTomita Hiroaki - Preterm birth affects approximately 5% to 7% of live births worldwide and is the leading cause of neonatal morbidity and mortality. Amniotic fluid supernatant (AFS) contains abundant cell-free nucleic acids (cfNAs) that can provide genetic information associated with pregnancy complications. In the current study, cfNAs of AFS in the early second-trimester before the onset of symptoms of preterm birth were analyzed, and we compared gene expression levels between spontaneous preterm birth (n = 5) and term birth (n = 5) groups using sequencing analysis. Differential expression analyses detected 24 genes with increased and 6 genes with decreased expression in the preterm birth group compared to term birth. Upregulated expressions of RDH14, ZNF572, VOPP1, SERPINA12, and TCF15 were validated in an extended AFS sample by quantitative PCR (preterm birth group, n = 21; term birth group, n = 40). Five candidate genes displayed a significant increase in mRNA expression in immortalized trophoblast HTR-8/SVneo cell with HO treatment. Moreover, the expression of five candidate genes was increased to more than twofold by pretreatment with lipopolysaccharide in HTR-8/SVneo cells. Changes in gene expression between preterm birth and term birth is strongly correlated with oxidative stress and infection during pregnancy. Specific expression patterns of genes could be used as potential markers for the early identification of women at risk of having a spontaneous preterm birth. - Source: PubMed
Publication date: 2022/03/31
Kim Min-ALee Eun-JuYang WookyeomShin Ha-YeonKim Young-HanKim Jae-Hoon