Ask about this productRelated genes to: ZNF264 antibody
- Gene:
- ZNF264 NIH gene
- Name:
- zinc finger protein 264
- Previous symbol:
- -
- Synonyms:
- KIAA0412
- Chromosome:
- 19q13.43
- Locus Type:
- gene with protein product
- Date approved:
- 1999-06-11
- Date modifiied:
- 2016-10-25
Related products to: ZNF264 antibody
Related articles to: ZNF264 antibody
- One-carbon nutrients and imprinted genes both play critical roles in placental development and somatic growth. We aimed to examine (1) the impact of maternal one-carbon nutrition on placental imprinted gene expression, placental development, and infant growth and (2) interactions between one-carbon nutrients and imprinted genes in placental development and infant growth. - Source: PubMed
Publication date: 2025/05/02
Gutherz Olivia RLi QianDeyssenroth MayaWainwright HelenJacobson Joseph LMeintjes Ernesta MChen JiaJacobson Sandra WCarter R Colin - Apelin, a bioactive peptide that serves as an endogenous ligand for the apelin receptor (APJ), is overexpressed in various types of cancers and contributes to cancer cell proliferation, viability, migration, angiogenesis, and metastasis, as well as immune deviation. Noncoding RNAs (ncRNAs) regulate gene expression, and there is growing evidence suggesting a bidirectional crosstalk between ncRNAs (including long noncoding RNAs [lncRNAs], circular RNAs [circRNAs], and microRNAs [miRNAs]) and apelin in cancers. Certain miRNAs can directly target the apelin and inhibit its expression, thereby suppressing tumor growth. It has been indicated that miR-224, miR-195/miR-195-5p, miR-204-5p, miR-631, miR-4286, miR-637, miR-4493, and miR-214-3p target apelin mRNA and influence its expression in prostate cancer, lung cancer, esophageal cancer, chondrosarcoma, melanoma, gastric cancer, glioma, and hepatocellular carcinoma (HCC), respectively. Moreover, circ-NOTCH1, circ-ZNF264, and lncRNA BACE1-AS upregulate apelin expression in gastric cancer, glioma, and HCC, respectively. On the other hand, apelin has been shown to regulate the expression of certain ncRNAs to affect tumorigenesis. It was revealed that apelin affects the expression of circ_0000004/miR-1303, miR-15a-5p, and miR-106a-5p in osteosarcoma, lung cancer, and prostate cancer, respectively. This review explains a bidirectional interplay between ncRNAs and apelin in cancers to provide insights concerning the molecular mechanisms underlying this crosstalk and potential implications for cancer therapy. - Source: PubMed
Jafarzadeh AbdollahNaseri BaharKhorramdelazad HosseinJafarzadeh SaraGhorbaninezhad FaridAsgari ZeynabMasoumi JavadNemati Maryam - Colorectal cancer (CRC) is a complex disease characterized by dynamically deregulated gene expression and crosstalk between signaling pathways. In this study, a new approach based on gene-function-based clusters was introduced to explore the CRC-associated networks of gene expression. Each cluster contained genes involved in coordinated regulatory activity, such as RAS signaling, the cell cycle process, transcription, or translation. A retrospective case-control study was conducted with the inclusion of 119 patients with histologically confirmed colorectal cancer and 308 controls. The quantitative expression data of 15 genes were obtained from the peripheral blood samples of all participants to investigate cluster-gene and gene-gene interactions. , , and were consistently selected as CRC-associated factors with high significance in all logistic models. became an insignificant factor only when combined with the clusters for cell cycle processes and for transcription. The complex was a prerequisite for the significance of , whereas , , , , and were affected by more than two clusters. Intricate networks among , RAS signaling factors (, , and ), and translation factors (, , and ) were also revealed. Our results suggest that limited G1/S transition, uncontrolled DNA replication, and the cap-independent initiation of translation may be dominant and concurrent scenarios in circulating tumor cells derived from colorectal cancer. This gene-function-based cluster approach is simple and useful for revealing intricate CRC-associated gene expression networks. These findings may provide clues to the metastatic mechanisms of circulating tumor cells in patients with colorectal cancer. - Source: PubMed
Publication date: 2023/01/06
Huang Chi-ShuanTerng Harn-JingHwang Yi-Ting - Epigenome-wide association studies have identified some DNA methylation sites associated with body mass index (BMI) or obesity. Studies in the Asian population are lacking. - Source: PubMed
Publication date: 2022/09/14
Chang RuixiaZhang YuanyuanSun JiahongXu KeLi ChunanZhang JingliMei WenhuaZhang HongzhongZhang Jianduan - Endometriosis is the most prevalent gynecological disease with elusive etiology. The mysterious entity and the lack of noninvasive diagnostic methods affect women's lives negatively. This study is aimed at finding the relationship between miR-340-5p, 92a-3p, and miR-381-3p and the pathogenesis of endometriosis in endometrial mesenchymal stem-like cells (eMSCs) of endometriosis and assessing their potential as a noninvasive biomarker in plasma. - Source: PubMed
Publication date: 2021/09/29
Bahramy AfshinZafari NargesIzadi PanteaSoleymani FatemehKavousi SaeidehNoruzinia Mehrdad