Ask about this productRelated genes to: Tal2 antibody
- Gene:
- TAL2 NIH gene
- Name:
- TAL bHLH transcription factor 2
- Previous symbol:
- -
- Synonyms:
- bHLHa19
- Chromosome:
- 9q31.2
- Locus Type:
- gene with protein product
- Date approved:
- 1990-07-15
- Date modifiied:
- 2016-10-05
Related products to: Tal2 antibody
Related articles to: Tal2 antibody
- Salt-tolerant phosphorus solubilizing fungi (PSF) play a pivotal role in plant growth promotion and P-nutrition in saline agro-ecoregions. Isolation and characterization of salt-tolerant fungi with P-solubilizing potential and plant growth promotion of sorghum at different salinity levels were conducted. - Source: PubMed
Publication date: 2025/09/29
Chandra PriyankaRai Arvind KumarBasak NirmalenduSundha ParulPrajapat KailashSingh AwtarMann AnitaYadav R K - - Source: PubMed
Publication date: 2025/03/27
Yao QiangChen JianxiaLuo MeizhuLin ZhenhuWang HongjianFu Xiaoying - This study explores the behavioral and molecular biological impacts of Fecal Microbiota Transplantation (FMT) on depressive mice unresponsive to treatment with Selective Serotonin Reuptake Inhibitors (SSRIs). - Source: PubMed
Publication date: 2025/02/18
Jiang YingShi LingyiQu YucaiOu MengmengDu ZhiqiangZhou ZhenheZhou HongliangZhu Haohao - Recent genomic research has identified several genetic factors contributing to B-cell acute lymphoblastic leukemia (B-ALL). However, the exact cause of the disease is still not fully understood. It is known that mutations in the TAL2 gene play important roles in the development of acute lymphoblastic leukemia. This study aimed to analyze the molecular and computational profile of the TAL2 mutations in a group of Iranian B-ALL patients for the first time. - Source: PubMed
Publication date: 2025/01/16
Khormizi Fateme ZareSaadi Hediye FahandezhKhatami MehriHeidari Mohammad MehdiTabrizi FatemeHashemi AzamKhanjarpanah Zohre - The mechanism underlying the differentiation of the dorsal midbrain into two morphologically and functionally distinct compartments, the inferior colliculus (IC) and superior colliculus (SC), which process auditory and visual information, respectively, remains largely unexplored. By using null and conditional alleles, we uncover the roles of a homeodomain transcription factor in the regulation of IC and SC differentiation. We show that regulates GABAergic neuron development in the dorsal midbrain. In the absence of function, the dorsal-most m1-m2 progenitor domains in the midbrain fail to activate GABAergic neuron-specific gene expression and instead switch to a glutamatergic phenotype. These results identify as a dorsal midbrain-specific GABAergic determinant that regulates the selector genes, , , and . Furthermore, we demonstrate that maturation of the dorsal midbrain into the IC and SC is dependent on . Null mutation of impairs the identity and fate of IC and SC neurons. Surprisingly, is required for preventing IC into SC fate switch and thus -deficient IC neurons undergo acquisition of SC identity. Conditional inactivation of at late developmental phase leads to alteration in the identity and fate of the IC, but not the SC. These results suggest that SC differentiation is dependent on the early function of , and that the IC requires the prolonged action for its normal formation. Furthermore, we uncover that acts downstream of selectively to promote IC differentiation. Altogether, our study identifies a molecular mechanism underlying spatial and temporal control of dorsal midbrain development. - Source: PubMed
Publication date: 2024/01/26
Tran Hong-NhungNguyen Quy-HoaiJeong Yongsu