Ask about this productRelated genes to: CD166 antibody
- Gene:
- ALCAM NIH gene
- Name:
- activated leukocyte cell adhesion molecule
- Previous symbol:
- -
- Synonyms:
- CD166, MEMD
- Chromosome:
- 3q13.11
- Locus Type:
- gene with protein product
- Date approved:
- 1997-01-17
- Date modifiied:
- 2016-10-05
Related products to: CD166 antibody
Related articles to: CD166 antibody
- To compare the spatiotemporal localization of Activated leukocyte cell adhesion molecule (Alcam; CD166) and Osterix (OSX), encoded by Sp7, an established odontoblast differentiation marker, during rat molar development using immunohistochemical approaches. - Source: PubMed
Publication date: 2026/08/09
Shibui ToruHosoya AkihiroTakahashi MasamiShibata ShunichiSeki-Kishimoto YuriTakebe HiroakiIrie Kazuharu - Genetic and preclinical data highlight CD6 as a promising target for multiple sclerosis (MS), yet the impact of clinically available CD6-targeting treatments on MS immunopathogenesis remains insufficiently defined. Itolizumab, a humanized anti-CD6 antibody with established safety and clinical efficacy in other autoimmune disorders, represents a potential candidate to interrogate this pathway in MS. - Source: PubMed
Publication date: 2026/07/21
González-Muñoz CynthiaBaeten PaulienHermans DoryssaHoeks CindyDe Bondt MirreDuran GayelWijmeersch Bart VanSchroten HorstIshikawa HiroshiCrombet-Ramos TaniaLabrada-Mon MayrelBroux BiekeHellings Niels - Cell replacement therapies aimed at restoring foveal vision require a robust source of red/green (long/medium wavelength, or L/M) cone photoreceptors with intrinsic properties conducive to functional integration into host retina. Recent evidence has shown that cones present within mature human retinal organoids (ROs) can generate light responses comparable to macaque foveal cones. However, only cone precursors from early developing ROs possess a capacity for cell-autonomous axonogenesis. Therefore, we sought to identify and enrich for a population of early L/M cone-competent precursors with intrinsically superior axon dynamics that would provide an ideal donor cell source for future foveal reconstruction efforts. - Source: PubMed
Publication date: 2026/07/04
Susaimanickam Praveen JCapowski ElizabethXiong Mai NEdwards Kimberly LPhanse YashdeepWelch Madalynn JPier AustinMayerl Steven JZepeda Maria A FernandezPeterson Kyle DPhillips M JosephSinha DivyaGomez Timothy MGamm David M - A subset of hormone-sensitive prostate cancer (HSPC) exhibits low prostate-specific membrane antigen (PSMA) uptake on PET imaging, which may limit the performance of PSMA-based detection and PSMA-directed therapeutic strategies. However, the clinical features and molecular basis of HSPC with low PSMA expression remain incompletely defined. - Source: PubMed
Publication date: 2026/07/03
Wu HaotianLi AngJiang ZhouZhang WeiweiShen KaiLiu BoSu RuopengLiu XinyuChai XinyuWang TianxiangWang JunyiYi JiayanZhou XiangZhu YinjieCao DengfengWang QiPan JiahuaXue Wei - TRPV4 is a non-selective cation channel of the TRPV family and plays a key role in fibrosis, but its pathological mechanisms in genetically susceptible individuals remain unclear. This study aimed to investigate the potential role of the c.1491+1G>A splice-site mutation in pulmonary fibrosis using a gene-edited mouse model. - Source: PubMed
Publication date: 2026/06/18
Ruan HaolongWang HaoboZhu ChengLi ZhihaoASu YuebumuJi ZihanLi YongGu LantaoFu CanYu HonghaoYue Pengpeng