Ask about this productRelated genes to: MYL3 antibody
- Gene:
- MYL3 NIH gene
- Name:
- myosin light chain 3
- Previous symbol:
- -
- Synonyms:
- CMH8, VLC1, MLC1V, MLC1SB
- Chromosome:
- 3p21.31
- Locus Type:
- gene with protein product
- Date approved:
- 1986-01-01
- Date modifiied:
- 2019-04-23
Related products to: MYL3 antibody
Related articles to: MYL3 antibody
- Conflicting evidence exists about whether sarcomeric hypertrophic cardiomyopathy (HCM) caused by genes encoding thin filament proteins (, ; thin filament HCM) has a distinct clinical presentation and natural history from disease caused by the more commonly involved thick filament genes (, , , ; thick filament HCM). - Source: PubMed
Publication date: 2026/09/24
Argirò AlessiaMeisner JoshuaAdler EricBertero EdoardoMaurizi NiccolòClaggett BrianLakdawala Neal KOwens AnjaliRyan Thomas DMiller Erin MSaberi SaraBundgaard HenningAxelsson Raja AnnaRossano Joseph WLin KimberlyGirolami FrancescaMichels MichelleZwetsloot Peter PaulAbrams DominicLampert RachelStendahl John CWare JamesParikh Victoria NAshley EuanIngles JodieGray BelindaCastillo Romi LTardiff JilCrotti LiaPereira AlexandreHo Carolyn YDay SharleneHelms AdamOlivotto Iacopo - Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are X-linked dystrophinopathies caused by mutations in the dystrophin (DMD) gene. A common DMD-causing mutation in humans is exon 52 deletion (DMDΔ52), which disrupts the reading frame and abolishes dystrophin expression. Therapeutic skipping of exon 51 or 53 can restore the reading frame, producing a truncated but functional protein and generating a BMD-like phenotype. Porcine models recapitulating DMDΔ52 (DMD) and DMDΔ51-52 (BMD-like) were used to identify molecular differences and condition-specific miRNA-mRNA networks. - Source: PubMed
Reschke SarahGraf AlexanderHadlich FriederJaudas FlorianFröhlich ThomasStirm MichaelKlymiuk NikolaiKrebs StefanWolf EckhardAli Asghar - Amyotrophic lateral sclerosis (ALS) likely has a prolonged presymptomatic phase. Identifying blood biomarkers that predict phenoconversion is critical for early intervention. - Source: PubMed
Publication date: 2026/09/03
Lehrer StevenRheinstein Peter H - Feed scarcity constrains livestock production, particularly on the Qinghai-Tibet Plateau. The effects of green alfalfa (GA) on Diqing Tibetan pig performance remain unclear. This study aimed to evaluate GA effects on Diqing Tibetan pig performance and to explore the potential underlying mechanisms through integrated metagenomic, transcriptomic, and metabolomic analyses. Thirty-six Diqing Tibetan pigs were randomly assigned to two groups and fed either a basal diet or a diet containing 90% basal diet and 10% GA. GA did not adversely affect growth performance but reduced 6-7 rib backfat thickness and muscle water loss rate by 19.79% (FDR = 0.027) and 17.80% (FDR = 0.036), while increasing muscle moisture content by 3.51% (FDR = 0.036). GA increased cecal microbial alpha diversity, Bacteroidota-related taxa, and functional genes related to lipid and vitamin metabolism, while decreasing Bacillota and . In the longissimus dorsi, , and were upregulated, whereas and were downregulated; GA increased vanillyl alcohol, L-histidine, LPE (0:0/22:5), and licochalcone B, but decreased glyceryl monostearate, benzaldehyde, cortisol, tryptamine, 4-ethyloctanoic acid, 8-methylnonanoic acid, and purine. Overall, 10% GA reshaped gut microbial, muscle transcriptomic, metabolomic profiles and collectively influenced 6-7 rib backfat thickness and muscle water-holding capacity in Diqing Tibetan pigs. - Source: PubMed
Publication date: 2026/07/17
Huang HeteLi XinpengZhang KangLiang BingkunBai SiyaDong XinxingYan Dawei - Apolipoprotein A-IV (apoA-IV) plays key roles in lipid metabolism, reverse cholesterol transport, and kidney function, yet its genetic determinants remain poorly defined. We conduct a genome-wide association study (GWAS) meta-analysis of apoA-IV concentrations measured by ELISA in 25,181 individuals and combine these with proteomic data from 33,995 UK Biobank participants (Olink platform), yielding a total sample of 59,176. We perform genetic correlations and colocalization analyses to explore links with lipid, renal, and other complex traits. - Source: PubMed
Publication date: 2026/07/14
Koller AdrianaSchnitzer FlorianKollerits BarbaraLamina ClaudiaMoix SamuelClaringbould AnniqueMishra Binisha HLu HaojieSchachtl-Riess Johanna FForer LukasGieger ChristianKheirkhah AzinLehtimäki TerhoMarques-Vidal PedroSchönherr SebastianStark Klaus JWürzner ReinhardEckardt Kai-UweHeid Iris MKavousi MaryamKöttgen AnnaRaitakari OlliSijbrands Eric J GPeters AnnetteVollenweider PeterKronenberg Florian