Ask about this productRelated genes to: REXO2 antibody
- Gene:
- REXO2 NIH gene
- Name:
- RNA exonuclease 2
- Previous symbol:
- -
- Synonyms:
- DKFZP566E144, SFN, CGI-114
- Chromosome:
- 11q23.2
- Locus Type:
- gene with protein product
- Date approved:
- 2005-08-19
- Date modifiied:
- 2015-08-25
Related products to: REXO2 antibody
Related articles to: REXO2 antibody
- The role of sodium-glucose cotransporter-1 (SGLT1) in mitochondrial biology function remains unclear. This study aimed to investigate the causal association between SGLT1 inhibition and mitochondrial biology function via Mendelian randomization (MR) analysis. - Source: PubMed
Publication date: 2026/03/13
Fan GangQu Zi-Han - Mitochondrial-related pathways (MRPs) play a crucial role in cancer metabolism and progression; however, their prognostic value in breast cancer (BC) is still poorly understood. - Source: PubMed
Publication date: 2026/02/16
Guo ZizhaoCao HengLei ChuqiMa DongxuWu JiangXing ZeyuZhao ChenyuWang XiangCui Jianxiu - Since the molecular characterization of periodic fever syndromes led to the concept of autoinflammation, the pace of scientific advancement in this field has been dramatic. Here, we review many of the most impactful new discoveries in autoinflammation, as presented at the 2024 Pediatric Rheumatology European Society Congress. This includes new genes and diseases, such as SHARPIN mutations and dominant-negative mutations in OTULIN as causes of disorders of ubiquitination, PMVK mutations as potential causes of a mevalonate kinase deficiency mimic, and ARF1 and REXO2 as causes of interferonopathy. Several new molecular mechanisms and mutations were also reported for older diseases including coatomer protein complex subunit alpha (COPA) syndrome, Aicardi-Goutières syndrome, PLCG2-associated immune dysregulation (PLAID), and NLRP3-AID. Finally, molecular and omics studies of STING1-associated vasculopathy with onset in infancy (SAVI) and haploinsufficiency of A20 (HA20) contributed to advances in underlying autoinflammatory biology. - Source: PubMed
Publication date: 2025/10/28
Schulert Grant S - Sepsis/septic shock frequently occurred as a lethal complication in the intensive care unit. Endoplasmic reticulum stress (ERS) leading to the disturbance of cellular proteostasis played an important role in the sepsis-induced multiple organ dysfunction. Previous studies showed that several ERS molecule were involved in. It is not clear which ERS molecule could be competent as prognostic indicators of sepsis. - Source: PubMed
Publication date: 2025/10/14
Zhou YuanqunXiang XinmingShe HanWu YueOuyang XingnanZhou XiaoweiYang ShunxinLiu LiangmingLi Tao - The heterogeneity of bladder cancer (BLCA) is affected by its inherent transcriptional properties and tumor microenvironment (TME). Stromal transcriptional components in the TME significantly influence the transcriptional classification of BLCA, and the intrinsic biological transcriptional characteristics of cancer cells may be obscured by the dominant, lineage-dependent transcriptional components of stromal origin. This study aimed to explore the degree and mechanisms by which cancer-intrinsic gene expression profiles contribute to the classification and prognosis of BLCA patients. - Source: PubMed
Publication date: 2025/06/17
Wang ZhanZhou ZhaokaiYang ShuaiLi ZhengruiShi RunWang RuizhiLiu KuiTang XiaojuanLi Qi