Ask about this productRelated genes to: PIGF antibody
- Gene:
- PGF NIH gene
- Name:
- placental growth factor
- Previous symbol:
- PGFL
- Synonyms:
- PLGF, PlGF-2, PlGF, SHGC-10760, D12S1900, PIGF
- Chromosome:
- 14q24.3
- Locus Type:
- gene with protein product
- Date approved:
- 1994-01-14
- Date modifiied:
- 2016-05-20
- Gene:
- PIGF NIH gene
- Name:
- phosphatidylinositol glycan anchor biosynthesis class F
- Previous symbol:
- -
- Synonyms:
- -
- Chromosome:
- 2p21
- Locus Type:
- gene with protein product
- Date approved:
- 1993-10-28
- Date modifiied:
- 2016-10-05
Related products to: PIGF antibody
Related articles to: PIGF antibody
- Serum placenta growth factor (PIGF), adiponectin, and endothelin-1 (ET-1) were associated with hypertension. However, it remains unclear whether these factors could predict the occurrence and prognosis of hypertensive disorders complicating pregnancy (HDCP). The enrolled pregnant women were classified into different groups according to diagnosis criteria. The demographic and clinical characteristics were compared among different groups. The levels of serum PIGF, adiponectin and ET-1 were determined. The predictive values of serum PIGF, adiponectin, and ET-1 for the occurrence and prognosis of HDCP were assessed using the receiver operating characteristic curve (ROC) analysis. There was a significant difference in systolic blood pressure, diastolic blood pressure, and proteinuria between the HDCP group and the normal pregnancy group. The level of serum PIGF and adiponectin decreased while ET-1 increased in the HDCP group compared to the normal pregnancy group. Furthermore, they had a similar change pattern with the progression of HDCP. The ROC analysis demonstrated that PIGF, adiponectin and ET-1 could effectively predict the occurrence and prognosis of HDCP. Compared to normal pregnant women, serum PIGF and adiponectin gradually decreased while ET-1 gradually increased with the progression of HDCP. Thus, they could effectively predict the occurrence and prognosis of HDCP. - Source: PubMed
Publication date: 2025/12/24
Liu ShashaLan QianyuLi WeilingLi YuanZhang JiefangFu LimanXu Yanlei - Fetal growth restriction complicates up to 10% of pregnancies, resulting in significant morbidity and mortality. Biomarkers of placental function, such as PIGF or the sFLT-1/PlGF ratio, are increasingly used in clinical practice, as an adjunct to ultrasound, with an aim of improving detection of the at-risk fetus and reducing morbidity and mortality. Current evidence suggests this combined approach is associated with improved prediction and hence prevention of adverse outcomes such as stillbirth, as well as optimizing delivery timing. Future research should focus on determining thresholds for intervention, possible therapeutic targets for angiogenic markers and provide cost-based analysis. Despite limitations, there is growing evidence to suggest placental biomarkers play an important role in the prenatal management of high-risk pregnancies. - Source: PubMed
Publication date: 2025/10/07
Bartels Helena CHobson Sebastian R - Pre-eclampsia causes adverse maternal and perinatal complications and is preventable through early screening and aspirin treatment. This study evaluates the predictive performance of the Fetal Medicine Foundation first-trimester preterm pre-eclampsia competing risks model in an Australian population. - Source: PubMed
Publication date: 2025/07/02
Tiruneh Sofonyas AbebawRolnik Daniel LorberSelvaratnam Roshanda Silva Costa FabricioMcLennan AndrewHyett JonTeede HelenaEnticott Joanne - To evaluate the association of PIGF and sFlt-1 with low birth weight and/or small-for-gestational age neonates in pregnancy with or without preeclampsia. - Source: PubMed
Publication date: 2025/03/31
Luo WenboTang PingpingLv YanSong YijunHu HuiyingGao JinsongLiu Juntao - Elevated worry is an early indicator of cognitive decline in older adults. Worry has been linked to pro-inflammatory processes though the exact relations between worry, inflammation, and cognition in older adults with amnestic mild cognitive impairment (aMCI) remain unexplored. The present study studied the association of worry with proteomic biomarkers of inflammation and cognition. - Source: PubMed
Publication date: 2025/02/27
Lam Jovian CLouras PeterSavettiere AdrianaFairchild J Kaci