Ask about this productRelated genes to: SLC14A1 antibody
- Gene:
- SLC14A1 NIH gene
- Name:
- solute carrier family 14 member 1 (Kidd blood group)
- Previous symbol:
- JK
- Synonyms:
- HsT1341, RACH1, RACH2
- Chromosome:
- 18q12.3
- Locus Type:
- gene with protein product
- Date approved:
- 1994-02-15
- Date modifiied:
- 2019-04-23
Related products to: SLC14A1 antibody
Related articles to: SLC14A1 antibody
- The aspiration of this review is to discuss the intricate development of Müller glial cells (MGCs) and their indispensable neuroprotective and regenerative roles, as well as novel avenues of treatment for retinal neurodegenerative diseases. MGCs are the principal radial glial cells of the vertebrate retina, extending from what is composed of a characteristic funnel-shaped morphology spanning throughout the retinal thickness. Their cell bodies are in the inner nuclear layer (INL), and their processes span from the outer limiting membrane to the inner limiting membrane, where they strongly associate with neurons, blood vessels, and the extracellular matrix across all layers of retinal structure. These cells preserve ionic and water homeostasis, control neurotransmitter uptake, and participate in constructing the blood retinal barrier (BRB), as well as deliver crucial metabolic help to neurons by means of the glutamate-glutamine cycle, thus excluding excitotoxic injury. - Source: PubMed
Publication date: 2026/05/09
Gupta PritiGopenath T SSingh Sandeep Kumar - Exposure to 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) may promote the initiation and progression of prostate cancer (PCa); however, its precise molecular mechanisms remain unclear. - Source: PubMed
Publication date: 2026/04/10
Wen YaoanYang JiangbinSu YuzheChen ShaoyuanZheng SongZhu ShaoxingChen GuoqiangZhan Shuyuan - The JK blood group system encodes the antithetical antigens Jk and Jkb as well as Jk3.1 on chromosome 18 spans approximately 28 kb and has 10 exons. The diallelic single nucleotide variant (SNV) c.838G>A p.(Asp280Asn) gives rise to the antithetical antigens Jk or Jkb, respectively. At the time of this publication and including this novel allele, there are 12 alleles encoding Jk(a+w) and 29 null alleles, and 6 alleles encoding Jk(b+w) and 30 null alleles. We describe two African American donors whose red blood cells (RBCs) tested Jk(a-b+) with polyclonal and monoclonal antisera. The RBC genotyping panel HemoID DQS (Agena Bioscience, San Diego, CA) predicted the sample to type Jk(a+b+). This discrepancy was investigated using Sanger sequencing of the coding exons and exon/intron junctions of - Source: PubMed
Publication date: 2026/04/10
Smith AlexisYu Mary VijimMansfield PaulRosa Isabella MKeller Margaret A - Stomatin is a ubiquitous and highly expressed protein in erythrocytes, which associates with cholesterol-rich microdomains in the plasma membrane and is known to regulate the activity of multiple ion channels and transporters, but the structural basis of association with stomatin targets remains unknown. Here, we describe high-resolution structures of multiple stomatin complexes with endogenous binding partners isolated from human erythrocyte membranes, revealing that stomatin specifically associates with two membrane proteins involved in water transport and cell volume regulation, aquaporin-1 and the urea transporter SLC14A1. Together, our results reveal the structural basis of stomatin oligomerization, membrane association, and target recruitment and identify a putative role for stomatin in the regulation of osmotic balance in the erythrocyte. - Source: PubMed
Publication date: 2026/04/01
Vallese FrancescaLi HuanBarazzuol LuciaCalì TitoClarke Oliver B - Dermatomyositis is a common immune-mediated skin disorder whose pathogenesis has not been fully elucidated. Environmental factors play a key role in its onset and progression. Bisphenol A (BPA) is a widespread environmental pollutant known to pose risks to human health. Previous studies have indicated that BPA exposure can disrupt immune function and trigger skin inflammation and autoimmune diseases. However, the role and molecular mechanisms of BPA in dermatomyositis remain unclear. This study aims to systematically elucidate whether and how bisphenol A (BPA) may contribute to the development of dermatomyositis by identifying key toxicological targets and underlying molecular mechanisms through an integrated computational framework. - Source: PubMed
Publication date: 2026/03/30
Cheng LiliTang ZhongfuLi MingHuang Chuanbing