Ask about this productRelated genes to: SEMA4F antibody
- Gene:
- SEMA4F NIH gene
- Name:
- ssemaphorin 4F
- Previous symbol:
- SEMAM
- Synonyms:
- SEMAW
- Chromosome:
- 2p13.1
- Locus Type:
- gene with protein product
- Date approved:
- 1999-06-25
- Date modifiied:
- 2016-01-14
Related products to: SEMA4F antibody
Related articles to: SEMA4F antibody
- Hepatocellular carcinoma (HCC) is the most common pathological type of liver cancer. SEMA4F is an immune-related gene associated with HCC survival. As a transmembrane semaphorin, semaphorin 4F plays a key role in various biological processes. Recent studies have found that semaphorin 4F is closely related to cancer progression, but its role in HCC remains unclear. In this study, we aimed to investigate the function and related mechanisms of SEMA4F in HCC. - Source: PubMed
Publication date: 2026/04/24
Wang Jing-JingXie LeiWang XiangChen Xing-YuXu XiaoZhai Ping-PingXu Zhi-ZhengChen Kai - Cachexia is an extrapulmonary manifestation of Chronic Obstructive Pulmonary Disease (COPD) characterized by weight loss and muscle wasting. Transcriptomic profiling of biopsies enables profiling of COPD-cachexia relevant dysregulation. As obtaining muscle biopsies is invasive and yields limited tissue, human muscle derived cultures (HMDC) may enable mechanistic research into cachexia. However, questions remain regarding the extent to which HMDC recapitulate transcriptomic signatures of bulk skeletal muscle in COPD-cachexia. To address this gap, we tested whether COPD and COPD-cachexia associated transcriptional dysregulation signatures in bulk skeletal muscle are preserved in derived myoblasts, myocytes, and myotubes. - Source: PubMed
Publication date: 2025/12/05
Sothers HannaLukusa-Sawalena BitotaLavin Kaleen MMa WenxiaChiles Joe WCasaburi RichardPatel RakeshWells J MichaelKazamel MohamedRossiter Harry BThalacker-Mercer AnnaMcDonald Merry-Lynn N - Clinical outcomes in neuroblastoma (NB) are closely linked to its differentiation status, making the reversal of differentiation arrest a highly promising therapeutic objective. However, the mechanisms that govern neuronal differentiation in NB remain unclear. In this study, we identify TRIM59 as a key regulator of RNA splicing that drives NB differentiation via an SFPQ-dependent mechanism. - Source: PubMed
Publication date: 2025/12/18
Zhang YingwenYang YiChen GuoyuYin MinzhiGao YijinLi YanxinFeng Haizhong - Semaphorin4F (Sema4F) is a member of the semaphorin family and exhibits important regulatory functions in cancer biology. We aimed to explore the prognostic value and biologic function of Sema4F in gastric cancer (GC) through clinical data, laboratory studies, and bioinformatic methods. - Source: PubMed
Publication date: 2023/09/15
Wang HuixuanJi XiangChen LinJu LinlingMa QinrongWu YijingCai Weihua - The mechanism by which infiltrating CD8+ T lymphocytes in the tumour microenvironment influence the survival of patients with ovarian cancer (OC) remains unclear. - Source: PubMed
Publication date: 2023/08/28
Zhu YunshuLiang LeileiLi JianZeng JiaYao HongwenWu Lingying