Ask about this productRelated genes to: MARVELD3 antibody
- Gene:
- MARVELD3 NIH gene
- Name:
- MARVEL domain containing 3
- Previous symbol:
- MRVLDC3
- Synonyms:
- -
- Chromosome:
- 16q22.2
- Locus Type:
- gene with protein product
- Date approved:
- 2004-03-15
- Date modifiied:
- 2014-11-19
Related products to: MARVELD3 antibody
Related articles to: MARVELD3 antibody
- The present study analyzed the specific function of MARVEL domaincontaining protein 3 (MARVELD3) in esophageal cancer (EC). - Source: PubMed
Publication date: 2026/07/24
Fan WenboHuang ChunyaoWang ZhulinSun ShaowuLi KaiyuanLiu XuWang ZelongZhao TianliangZhang GuoqingPan Xue - The pervasive environmental presence of nano- and microplastics, particularly polystyrene nanoplastics (PSNPs), has raised increasing concern regarding their potential adverse effects on human health. While epithelial barrier impairment is recognized as a critical toxicological outcome, the oral epithelium remains a poorly understood target despite being the primary gateway for ingested nanoplastics. In this study, we demonstrate that PSNPs induce significant functional impairment of the oral barrier even under sub-cytotoxic conditions (>80% cell viability). Exposure of TR146 human buccal epithelial cell layers to PSNPs triggered an early increase in paracellular permeability (fluorescein isothiocyanate-labeled dextran (4 kDa) flux), followed by a decline in transepithelial electrical resistance. Crucially, these functional deficits occurred in the absence of overt cytotoxicity and were associated with the molecular downregulation and altered distribution of tight junction-related proteins, including ZO-2, occludin, MarvelD3, and claudin-3 and claudin-4. Our findings indicate that PSNP-induced alterations in TJ-related protein distribution may represent an early molecular event associated with oral epithelial barrier dysfunction under sub-cytotoxic conditions. Collectively, this study highlights the oral epithelium as a highly sensitive target and underscores that functional barrier failure, rather than direct cytotoxicity, may represent a key mechanism underlying nanoplastic-associated toxicity. - Source: PubMed
Publication date: 2026/05/02
Park Ha-YoungShin Soo-Bin - Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder characterized by obsessions and compulsions, with a prevalence of 1%-3%. Tight junction (TJ) proteins contribute to maintaining the epithelial barrier. This study investigated the association of serum TJ-associated MARVEL protein family and inflammatory markers with OCD severity in children and adolescents. - Source: PubMed
Publication date: 2026/03/31
Ünal KübranurTorun Yasemin TaşErol Mehmet EmreKurt Zeynep KübraÖzbaş Cansu - Modern swine breeding has been shifted from maximizing productivity to improving quality for better efficiency. A key goal is to balance litter size with piglet birth weight (BW). This study focused on Danish Large White pigs to evaluate a novel placental efficiency (PEA) index based on placental area (PA) as a biologically relevant and measurable trait for breeding programs. - Source: PubMed
Publication date: 2026/04/02
Yu Shi XinCui Sheng DiChen DongZhao Zhen JianTecku Patrick Kofi MakafuiChen Jia MiaoHuang Run JieZhou Yao XiTang Guo Qing - Esophageal cancer (ESCA) carries a poor prognosis, and the exploration of mRNA vaccines for its treatment remains limited. This study aims to identify potential tumor antigens and characterize the immune landscape, thereby providing a foundation for developing mRNA vaccines against ESCA. - Source: PubMed
Publication date: 2025/11/26
Zhang ZeweiHou JixiangWang YingxueJiang YingWang WenjuanZhao JuanJin GaowaZhao LeiLi Quanfu