Ask about this productRelated genes to: IMPAD1 antibody
- Gene:
- IMPAD1 NIH gene
- Name:
- inositol monophosphatase domain containing 1
- Previous symbol:
- -
- Synonyms:
- FLJ20421, IMPA3, gPAPP
- Chromosome:
- 8q12.1
- Locus Type:
- gene with protein product
- Date approved:
- 2005-08-02
- Date modifiied:
- 2016-10-07
Related products to: IMPAD1 antibody
Related articles to: IMPAD1 antibody
- To elucidate the role of miRNAs in porcine muscle tissues, this study used Solexa high-throughput sequencing to identify and compare differentially expressed miRNAs in Landrace pigs and the Diannan small ear pigs. - Source: PubMed
Publication date: 2025/07/23
Xie YuxiaoCheng WenjieHao MeilinYi Lan-LanZhu Jun-HongZhao Yan-GuangZhao Sumei - Perioperative delirium is a growing concern in the aging population, posing significant risks to frail elderly patients. While frailty is associated with delirium, the underlying mechanisms remain unclear. - Source: PubMed
Publication date: 2025/05/30
Tang JianQian ZhengyuZhu ZhengyinQin HongjinCai GuangyuWang YaqiWei ZhuRao XueLiu YangZou XiaohuaRen Yimin - Epidermal growth factor receptor (EGFR) mutation is common in Chinese patients with lung adenocarcinoma (LUAD). Brain metastases (BMs) is high and associated with poor prognosis. Identification of EGFR-mutant patients at high risk of developing BMs is important to reduce or delay the incidence of BMs. Currently, there is no literature on the prediction and modeling of EGFR brain metastasis at the proteinomics level. We conducted a retrospective study of BMs in postoperative recurrent LUAD with EGFR mutation in the First Affiliated Hospital of Guangzhou Medical University. Tissue proteomic analysis was applied in the primary tumors of resected LUAD in this study using liquid chromatography-mass spectrometry (LC-MS/MS). To identify potential markers for predicting LUAD BM, comparative analyses were performed on different groups to evaluate proteins associated with high risk of BMs. A combination of three potential marker proteins was found to discriminate well between distal metastasis (DM) and local recurrence (LR) of postoperative LUAD with EGFR mutation. Gene Ontology (GO) analysis of significantly altered proteins between BM and non-BM (NBM) indicated that lipid metabolism and cell cycle-related pathways were involved in BMs of LUAD. And the enriched pathways correlated with BMs were found to be quite different in the comparison groups of postoperative adjuvant therapy, tyrosine kinase inhibitor (TKI), and chemotherapy groups. Finally, we developed a random forest algorithm model with eight proteins (RRS1, CPT1A, DNM1, SRCAP, MLYCD, PCID2, IMPAD1 and FILIP1), which showed excellent predictive value (AUC: 0.9401) of BM in patients with LUAD harboring EGFR mutation. A predictive model based on protein markers was developed to accurately predict postoperative BM in operable LUAD harboring EGFR mutation. - Source: PubMed
Publication date: 2024/02/25
Deng QiuhuaWang FengnanSong LeiChen LiangyuHuang YingGuo ZhihuaYang Haihong - Fetal skeletal dysplasia is a diverse group of degenerative diseases of bone and cartilage disorders that can lead to movement disorder and even death. This study aims to evaluate the diagnostic yield of sonographic examination and genetic testing for fetal skeletal dysplasia. - Source: PubMed
Publication date: 2023/10/25
Liu WanluCao JingShi XinweiLi YuqiQiao FuyuanWu Yuanyuan - The therapeutic value of targeted therapies in patients with lung cancer is reduced when tumours acquire secondary resistance after an initial period of successful treatment. However, the molecular events behind the resistance to targeted therapies in lung cancer remain largely unknown. - Source: PubMed
Chen Qi WenCai Qian QianYang YingDong ShuLiu Yuan YuanChen Zhong YiKang Chun LanQi BingDong Yi WeiWu WeiZhuang Li PingShen Ye HuaMeng Zhi QiangWu Xing Zhong