Ask about this productRelated genes to: GPR177 antibody
- Gene:
- WLS NIH gene
- Name:
- Wnt ligand secretion mediator
- Previous symbol:
- C1orf139, GPR177
- Synonyms:
- FLJ23091, MRP, wls, EVI, mig-14
- Chromosome:
- 1p31.3
- Locus Type:
- gene with protein product
- Date approved:
- 2005-07-08
- Date modifiied:
- 2018-11-09
Related products to: GPR177 antibody
Related articles to: GPR177 antibody
- Corpus callosum abnormalities (CCA) represent a heterogeneous group of neurodevelopmental disorders resulting from disturbances in midline patterning, neuronal migration, and axonal guidance. Their genetic architecture includes chromosomal abnormalities, pathogenic copy-number variations (CNVs), and single-gene disorders; however, genotype-phenotype correlations remain incompletely defined, particularly in underrepresented populations. - Source: PubMed
Publication date: 2026/09/14
Khadija BochraAbdallah Hamza HadjSlimani WafaBennour AydaDimassi SarraSoyah NajlaBenzarti AmiraRjiba KhouloudDahleb WafaKammoun MolkaHannechi HanenKhelifa Hela BenKhouja Neziha GouiderBoughamoura LamiaKraoua IchrakTriki ChahnazTej AmelMathlouthi JihenGuith AidaAbroug SaoussenKebaili RaoudhaBouaziz Mohamed AliSoua HabibSboui EssiaHadded SamirZiadi RandaMonastiri KamelBen Hamida HayetGhanmi MonjiHassayoun SaydaSfar Mohamed TaharSaad AliDepienne ChristelMougou-Zerelli Soumaya - Understanding the cognitive architectures that enable learners to process feedback and self-regulate is fundamental to fostering intelligent second language (L2) learning, particularly as AI-based pedagogies become prevalent. Direct written corrective feedback, while common in beginner L2 writing, often triggers only surface-level processing. This study investigates whether written languaging (WL), a metacognitive activity where learners explain language problems in writing, can deepen feedback processing, thereby activating a more robust cognitive architecture for error correction. Using a within-subjects crossover design with 15 beginner Chinese-as-a-second-language (CSL) learners from a UK secondary school, we compared the immediate and transfer effects of direct feedback with WL versus direct feedback only. Results showed that the WL condition significantly reduced errors per 100 characters (Z = -2.556, = .011, r = 0.66), with 86.7% of participants showing improvement, indicating enhanced cognitive regulation at the local level. However, the effect was hierarchical, with no significant impact on clause-level accuracy. General Certificate of Secondary Education (GCSE) writing scores improved significantly from pre-to-post-test (Z = -3.342, = .001, r = 0.89), demonstrating transfer to subsequent performance. Qualitative analyses revealed that learners' attention focused predominantly on characters (48.4%) and vocabulary (29.8%), with engagement moderated by proficiency and motivation. This study provides empirical evidence for a cognitive architecture of feedback processing, wherein WL functions as a metacognitive amplifier. This architecture is operationalised as a three-stage processing sequence noticing, hypothesis-testing, and metalinguistic reflection, with writing accuracy and WL texts serving as observable proxies for the underlying cognitive processes. Specifically, our findings reveal that WL's facilitative effects are hierarchical, strongest at the level of local error reduction and not yet extending to clause-level syntactic accuracy, and are moderated by individual differences in proficiency and motivation. These empirical insights offer a cognitive-psychological foundation that could inform the future design of adaptive feedback systems; however, as this study did not involve any AI system, these implications are theoretical and await empirical validation in AI-mediated learning environments. - Source: PubMed
Publication date: 2026/09/19
Lyu MingYang BaoqianHe Wenting - Delirium is a frequent acute neuropsychiatric complication in critically ill surgical patients and is associated with poor clinical outcomes. Nutritional-metabolic disturbances, including insulin resistance and stress-related glycemic dysregulation, may contribute to delirium susceptibility. This study investigated the independent and joint associations of the triglyceride-glucose index (TyG) and stress hyperglycemia ratio (SHR) with delirium in critically ill surgical patients. - Source: PubMed
Publication date: 2026/09/09
Yao FengweiWu LinquanLi Enliang - Acute kidney injury (AKI) is a critical clinical syndrome with limited curative therapies. Tubular epithelial cell death is a central event in AKI progression in which ferroptosis plays a pivotal role. Pharmacological inhibition of ferroptosis attenuates renal inflammation and preserves kidney function, positioning it as a promising therapeutic strategy for AKI. Wuling powder (WLS) is a classic formula used for kidney diseases; however, whether it confers renoprotection by modulating ferroptosis in AKI remains unclear. - Source: PubMed
Publication date: 2026/09/11
Xiong JingliLong ZiyuMa JiayiJiang HuilianYe JiewenZeng ZhijunLiao YonganLao BeiniZhou YuanYu YangZhou Jiuyao - In Global Navigation Satellite System (GNSS)-denied indoor environments, ultra-wideband (UWB) localization of unmanned ground vehicles (UGVs) is challenged by position-dependent anchor visibility and mixed line-of-sight (LOS)/non-line-of-sight (NLOS) ranging. This study proposes a soft continuous confidence weighting method within an adaptive Kalman filter (AKF)-based UWB/inertial measurement unit (IMU) localization framework. The vehicle model uses motor pulse increments and IMU yaw-rate measurements as inputs and outputs vehicle position and heading estimates. Virtual forward-backward iteration converts inconsistencies between the current UWB ranges and tag-anchor geometry into terminal virtual-anchor displacements. A half-Gaussian function then maps each displacement to a continuous confidence coefficient. The resulting coefficients are incorporated into weighted least-squares (WLS) and AKF localization, while the UWB measurement-noise covariance is adaptively updated using the range innovations. The proposed method was evaluated through static calibration and dynamic localization experiments. These experiments compared soft and hard weighting schemes and assessed the contribution of AKF fusion. These results indicate that the method proposed in this study improves localization accuracy, robustness, and temporal continuity under position-dependent anchor visibility and mixed LOS/NLOS conditions. - Source: PubMed
Publication date: 2026/08/17
Yang YufeiLiu Wei