Ask about this productRelated genes to: CHIA antibody
- Gene:
- CHIA NIH gene
- Name:
- chitinase acidic
- Previous symbol:
- -
- Synonyms:
- AMCase, TSA1902, CHIT2
- Chromosome:
- 1p13.2
- Locus Type:
- gene with protein product
- Date approved:
- 2005-08-16
- Date modifiied:
- 2019-01-21
Related products to: CHIA antibody
Related articles to: CHIA antibody
- Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) is an emerging therapeutic option for peritoneal carcinomatosis, offering improved drug distribution and tissue penetration. Although clinical outcomes have been encouraging, international guidelines for perioperative management - including pain control and thromboprophylaxis - are still lacking. - Source: PubMed
Publication date: 2026/05/08
Fawaz JadeHübner MartinEzanno Anne-CécileTaibi AbdelkaderKepenekian VahanEveno ClarisseAlyami Mohammad SalehMalgras BricePocard Marc - TQB2102, a next-generation biparatopic antibody-drug conjugate (ADC) targeting humanized epidermal growth factor receptor 2 (HER2) extracellular domain 2 (ECD2) and ECD4 epitopes, conjugated to a topoisomerase I inhibitor via an enzyme-cleavable linker. This study evaluated the safety, efficacy, and pharmacokinetics of TQB2102 in patients with advanced solid tumors. - Source: PubMed
Publication date: 2026/05/15
Ruan D YLin S YHuang J JLi Y HLi NQu X JDu X BYin Y MYuan Z YShi Y XXu FAn XHong R XXia WXue CBi X WJiang K KZheng Q FZhang Y QPeng J JLiu Z YXiong H HSuo A LLin R BZhang STang S NYu YLi XWang XTian XLv PShen CLou L GWang LZhang Z PXu T JChen T XWang S SXu R H - The purpose of this study was to investigate the effects of caffeinated chewing gum on the cognitive tasks, strength and military performance of tier 1 special forces soldiers in Taiwan. - Source: PubMed
Publication date: 2026/05/16
Shiu Yi-JieChen Che-HsiuLin Hung-YuYang Chia-ChengYen Chi-WenChang Han-YuanChen Hsuan-TaChiu Chih-Hui - To evaluate whether initiation of different second-line glucose-lowering therapies is associated with the risk of total joint replacement (TJR) among patients with type 2 diabetes (T2DM). - Source: PubMed
Publication date: 2026/05/08
Liu Che-YuYu Hui-ITsai Ching-FangWu Cheng-YiYang Hsin-Yi - Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are widely used for the management of type 2 diabetes mellitus (T2DM) due to their metabolic and cardiovascular benefits; however, concerns have emerged regarding potential neuropsychiatric effects, including depression. This systematic review and meta-analysis aimed to evaluate the association between GLP-1 RA use and the risk of developing depression in adults with T2DM. A systematic search of PubMed, Embase, Scopus, Web of Science, and the Cochrane Library was conducted from database inception through April 2025 to identify randomized controlled trials and observational studies comparing GLP-1 RAs with other antidiabetic therapies. The primary outcome was incident depression. Secondary outcomes included anxiety-related outcomes and reported adverse events. Risk of bias was assessed using the Risk of Bias in Non-randomized Studies of Interventions (ROBINS-I) tool and the Newcastle-Ottawa Scale, where appropriate. Pooled hazard ratios (HRs) with 95% confidence intervals (CIs) were calculated using a random-effects model. Nine studies involving 1,735,325 patients met the inclusion criteria, of which five contributed to the quantitative synthesis. The meta-analysis demonstrated no statistically significant difference in the risk of incident depression between GLP-1 RA users and those receiving other antidiabetic agents (HR 1.05; 95% CI 0.97-1.14), with substantial heterogeneity observed (I² = 83.2%). Sensitivity analysis showed that exclusion of one influential study increased the pooled estimate to a statistically significant hazard ratio (HR 1.09; 95% CI 1.01-1.19; p = 0.035). Limited evidence suggested potential benefits in anxiety-related outcomes in some studies, although findings were heterogeneous and not amenable to quantitative synthesis. Reported adverse events were predominantly gastrointestinal. Overall, the available evidence suggests that GLP-1 RA use is not associated with an increased risk of depression in adults with type 2 diabetes, though heterogeneity across studies highlights the need for further prospective research with standardized psychiatric outcome assessment. - Source: PubMed
Publication date: 2026/04/13
Ferrer Zavala Genesis MCaro Rodriguez Cesar FCarrion Carrion PaulaMartinez Artiga LeslyMorales Del Cid Zuleika YChia Jia EeValladares Carlos