Ask about this productRelated genes to: RASGEF1C antibody
- Gene:
- RASGEF1C NIH gene
- Name:
- RasGEF domain family member 1C
- Previous symbol:
- -
- Synonyms:
- FLJ35841
- Chromosome:
- 5q35.3
- Locus Type:
- gene with protein product
- Date approved:
- 2004-02-04
- Date modifiied:
- 2015-11-09
Related products to: RASGEF1C antibody
Related articles to: RASGEF1C antibody
- New methods estimate amyloid positivity onset age (EAOA) from amyloid positron emission tomography (PET). We explore the genetics of EAOA to identify molecular factors underlying the earliest Alzheimer's disease (AD) changes. - Source: PubMed
Castellano TonnarWang Ting ChenNolan EmmaWu YiyangZhang MengnaClifton MichelleJanve Vaibhav ADurant AlainaRegelson AlexisCody KarlyHarrison TheresaEngelman Corinne DJagust WilliamAlbert MarilynJohnson SterlingResnick Susan MSperling ReisaBilgel MuratSaykin AndrewVardarajan BadriMayeux Richard Betthauser TobeyBennett David ASchneider JulieDe Jager PhilMenon VilasTosun DuyguMormino ElizabethArcher Derek BDumitrescu LoganHohman Timothy JKoran Mary Ellen - This study seeks to identify a non-invasive biomarker for preeclampsia (PE), given its considerable influence on both maternal and fetal health. - Source: PubMed
Publication date: 2025/09/19
Rashid Teeba AmmarFarhan Shahd RajabKhalaf Aysar AshourSanghvi GauravUthirapathy SubasiniJyothi RenukaKundlas MayankJoshi Kamal KantRudova AnnaMustafa Yasser Fakri - The incidence of thyroid cancer (TC) has significantly increased, highlighting the need for effective and objective approaches for the early diagnosis of TC. This study aimed to explore RASGEF1C methylation as a biomarker for papillary thyroid cancer (PTC). - Source: PubMed
Publication date: 2025/07/14
Yu WenkangYin YifeiLi MengxiaHuang HaixiaLi JunjieZhang YiZhu LunZhang YifenHuang XuandongJiang ChenxiaYang Rongxi - RasGEF domain family member 1C (RASGEF1C), primarily acting in neurological disorders, remains largely enigmatic regarding its function in lung cancer (LC). - Source: PubMed
Publication date: 2025/06/23
Wu HaoZheng KangHan Fei - Lung adenocarcinoma (LUAD) is a common histologic lung cancer with high morbidity and mortality, and most patients have distant metastases at diagnosis. RasGEF Domain Family Member 1C (RASGEF1C) could regulated Alzheimer's disease. However, its function in various cancers, including LUAD, is poorly understood. In the present study, we discovered that high expression of RASGEF1C in LUAD was associated with poorer prognosis, unfavorable histological features, and poorer pathological staging. In addition, RASGEF1C expression was an independent predictor of overall survival, disease specific survival, and progress free interval in patients with LUAD. High expression of RASGEF1C was linked to signaling pathways that are involved in the immune response and cell proliferation, according to KEGG enrichment analysis. Additionally, we verified that RASGEF1C was highly expressed in LUAD cell lines and that RASGEF1C knockdown dramatically decreased the capacity of LUAD cell lines to invade, migrate, and proliferate. Our research provides mechanistic insights into the function of RASGEF1C in the progression of LUAD and suggests that RASGEF1C is a prospective target for future therapy. - Source: PubMed
Publication date: 2024/12/23
Liu JinlongLiu XiaoyingZeng YingouQiao DiDai BinWu YunlongWang MengWang Qiang