Ask about this productRelated genes to: CD160 antibody
- Gene:
- CD160 NIH gene
- Name:
- CD160 molecule
- Previous symbol:
- -
- Synonyms:
- BY55, NK1, NK28
- Chromosome:
- 1q21.1
- Locus Type:
- gene with protein product
- Date approved:
- 2003-10-02
- Date modifiied:
- 2016-10-05
Related products to: CD160 antibody
Related articles to: CD160 antibody
- How gut microbiota alterations may contribute to host inflammation and metabolomic profiles affecting atherosclerosis is not fully elucidated, especially in the context of HIV. - Source: PubMed
Publication date: 2026/05/04
Wang ZhengWang YiPeters Brandilyn APost Wendy SBrown Todd TPalella Frank JRinaldo Charles RWitt Mallory DGange Stephen JKuniholm Mark HSha Beverly EChichetto Natalie EClish Clary BGerszten Robert EHodis Howard NSharma AnjaliAnastos KathrynBurk Robert DKaplan Robert CQi QibinHanna David B - To investigate the expression patterns of CD95 and CD160 on double-negative T (DN T) cells and their association with incomplete immune reconstitution in people living with HIV. - Source: PubMed
Publication date: 2026/04/16
Peng JingliLi YanyanXi JialeXia ZihaoLuo PingYang ShuoLu LianfengChen ChenCai RentianWang QinWei Hongxia - Natural killer (NK) cells play a pivotal role in anti-tumor immunity; however, the prognostic significance of genetic variants in NK cell-related genes in gastric cancer (GC) remains largely uncertain. - Source: PubMed
Publication date: 2026/04/15
Zeng GuangLu GuoqiangHu BeipingXu MidieLi GuanlinWang MengyunQiu LixinZhang RuoxinCheng LeiXu WanghongLiu XiaowenJin GuangfuLiu HongliangWei Qingyi - Preeclampsia is a multifactorial pregnancy complication characterized by hypertension and immune dysregulation, which can lead to adverse maternal and fetal outcomes. Decidual immune cells are critical for pregnancy homeostasis, yet their functional abnormalities and mechanisms in preeclampsia remain poorly understood. Herein, we sorted decidua immune cells from preeclampsia patients for single-cell RNA sequencing to characterize cellular composition and functional heterogeneity. We delineated the immune cell landscape of the decidua in preeclampsia. A hallmark of decidual immune microenvironment in preeclampsia was the marked augmentation of cytotoxic activity. Both NK and T cells exhibited enhanced cytotoxic activity, characterized by the significant upregulation of cytotoxicity-associated genes. NK cells exhibited a differentiation predisposition toward a unique tissue-resident ITGAECD160 subset with heightened cytotoxic and chemokine gene expression. Cell-cell communication analysis further revealed strengthened interactions between NK cells and macrophages, with macrophage-derived SPP1 signals potentially contributing to the amplification of local cytotoxic responses. Collectively, this study provides a comprehensive single-cell analysis of cytotoxic immune changes at the maternal-fetal interface in preeclampsia, revealing enhanced cytotoxicity that may represent a key pathological mechanism. These insights may inform the development of diagnosis and therapeutic strategies targeting cytotoxic immune dysregulation in PE. - Source: PubMed
Publication date: 2026/04/16
Mu YueliLiu DongHe ZhuoxuWang JulinZhou WenjieChen HongqinZhou ShengpingFeng TingZhou RongLi Hong - Sea turtles are among the many wildlife species adversely affected by Florida red tide, Karenia brevis. This marine dinoflagellate blooms almost annually along Florida's west coast and produces brevetoxins, a suite of potent neurotoxins. Brevetoxins can reach carnivorous loggerhead and Kemp's ridley sea turtles via aerosols and marine food webs, leading to multi-system physiological effects. Sea turtles stranded during red tide can be rescued, transported to rehabilitation facilities, and given palliative care with the goal of return to the wild. However, there are no definitive diagnostic criteria for brevetoxicosis other than stranding in association with red tide. Often sea turtles experience delayed exposure due to the long temporal scale of trophic transfer of toxins. To identify exposure biomarkers and to better understand the mechanism of toxicity of brevetoxins, plasma samples from red-tide exposed and healthy loggerhead and Kemp's ridley sea turtles were analyzed via bottom-up TMT-labeled quantitative liquid chromatography tandem mass spectrometry-based proteomics. Multiple sea turtle plasma protein abundances were significantly altered in red tide exposed turtles, including several immune system proteins like serum amyloid A5 (SAA-5; loggerheads) and CD160 antigen (Kemp's ridley). Pro-inflammatory markers serum amyloid A (SAA) and myeloid-related protein 126 (MRP-126) were measured independently in plasma of loggerhead turtles, with significant increases in these markers with red tide toxin exposure. The two species also differed in their proteomic response to red tide, indicating distinct biomarker candidates. Amid intensifying red tide events and the endangered status of these species, our findings provide a foundation for biomarker-based diagnosis of brevetoxicosis in sea turtles. - Source: PubMed
Publication date: 2026/04/13
Ceballos CelinaRein Kathleen SWalsh Catherine J