Ask about this productRelated genes to: ANGPTL5 antibody
- Gene:
- ANGPTL5 NIH gene
- Name:
- angiopoietin like 5
- Previous symbol:
- -
- Synonyms:
- -
- Chromosome:
- 11q22.1
- Locus Type:
- gene with protein product
- Date approved:
- 2002-11-13
- Date modifiied:
- 2016-10-04
Related products to: ANGPTL5 antibody
Related articles to: ANGPTL5 antibody
- Keloids are fibroproliferative skin tumors with excessive collagen deposition and are strongly linked to adipocytokine dysregulation. However, the underlying mechanisms remain unclear. This study aimed to identify potential therapeutic targets and elucidate adipocytokine-related pathological mechanisms underlying keloid formation. - Source: PubMed
Publication date: 2026/03/11
Mahemuti MaisudeCheng YouyouLi MinxuanYilihamu Alimire - Triple-negative breast cancer (TNBC) is a heterogeneous and aggressive subtype of breast cancer associated with poor clinical outcomes. Although programmed death ligand 1 (PD-L1) expression has emerged as both a prognostic and predictive biomarker, its utility remains limited, especially in PD-L1-negative tumors. The identification of additional molecular markers is crucial for improving prognostic stratification and guiding treatment strategies. - Source: PubMed
Publication date: 2025/11/28
Lee SeungjuKim Hyun YulJung Youn JooKang Seok-KyungRyu MiriLee MeehyunLee Sun MinOh Seung HwanLee JieonJeong SeongdoKang JunhoKim Jee Yeon - Photoperiod can regulate the broodiness of geese and thus increase their egg-laying rate. The laying performance of geese is mainly determined by ovary and follicle development. To understand the effect of photoperiod on the ovary and small white follicles, sixteen 220-day-old healthy female Zhedong white geese were randomly divided into two groups for long photoperiods (15L:9D) and short photoperiods (9L:15D). The geese were euthanized after two months of feeding, and their ovaries and follicles were collected for transcriptome sequencing. RNA-seq analysis identified 187 and 448 differentially expressed genes in ovaries and small white follicles of different photoperiod groups, respectively. A long photoperiod promotes high expression of , , , and genes in the ovaries, and increases the expression of , , , and genes in small white follicles. Functional enrichment analysis showed that photoperiod could affect respiratory system development, smooth muscle cell proliferation in ovaries, and extracellular matrix-related function in small white follicles. WGCNA revealed 31 gene modules, of which 2 were significantly associated with ovarian weight and 17 with the number of small white follicles. Our results provide a better understanding of the molecular regulation in the photoperiod affecting goose reproduction. - Source: PubMed
Publication date: 2024/09/23
Huang TaoFei MeinaZhou XiaolongHe KeYang SongbaiZhao Ayong - Variation in fin shape is one of the most prominent features of morphological diversity among fish. Regulation of fin growth has mainly been studied in zebrafish, and it is not clear whether the molecular mechanisms underlying shape variation are equally diverse or rather conserved across species. In the present study, expression levels of 37 candidate genes were tested for association with fin shape in the cichlid fish . The tested genes included members of a fin shape-associated gene regulatory network identified in a previous study and novel candidates selected within this study. Using both intact and regenerating fin tissue, we tested for expression differences between the elongated and the short regions of the spade-shaped caudal fin and identified 20 genes and transcription factors (including , , , , , , and ), whose expression patterns were consistent with a role in fin growth. Collated with available gene expression data of two other cichlid species, our study not only highlights several genes that were correlated with fin growth in all three species (e.g., , , , and ), but also reveals species-specific gene expression and correlation patterns, which indicate considerable divergence in the regulatory mechanisms of fin growth across cichlids. - Source: PubMed
Publication date: 2022/11/18
Ahi Ehsan PashayRichter FlorianSefc Kristina M - Esophageal cancer (EC) is a common malignant tumor of the digestive system with high mortality and morbidity. Current evidence suggests that immune cells and molecules regulate the initiation and progression of EC. Accordingly, it is necessary to identify immune-related genes (IRGs) affecting the biological behaviors and microenvironmental characteristics of EC. - Source: PubMed
Publication date: 2022/12/23
Li ChunzhenZhou WeizhengZhu JiShen QiWang GuangjieChen LingZhao Tiejun