Ask about this productRelated genes to: ENPP6 antibody
- Gene:
- ENPP6 NIH gene
- Name:
- ectonucleotide pyrophosphatase/phosphodiesterase 6
- Previous symbol:
- -
- Synonyms:
- MGC33971
- Chromosome:
- 4q35.1
- Locus Type:
- gene with protein product
- Date approved:
- 2003-11-25
- Date modifiied:
- 2014-11-19
Related products to: ENPP6 antibody
Related articles to: ENPP6 antibody
- The EAT Lancet diet is increasingly recognized for its simultaneous benefits to human and planetary health. Its key components are known to exert anti-inflammatory and antiplatelet effects; however, the potential association between adherence to the EAT‑Lancet diet and incident venous thromboembolism (VTE), as well as the underlying biological mechanisms, remains unclear. - Source: PubMed
Publication date: 2026/04/29
He QidaSun MengtongWang YuYao JiazhenShen Yueping - Alzheimer's disease with psychosis (AD+P) is a subgroup of AD patients with more rapid cognitive deterioration. While our previous study showed that AD+P is associated with loss of prefrontal cortex postsynaptic density (PSD) proteins, identifying proteins in the broader cellular environment that influence PSD loss addresses a critical knowledge gap about synaptic dysfunction mechanisms in early disease stages. - Source: PubMed
Publication date: 2025/12/01
Ku T SMullett S JSui ZZeng LDing YYocum A KMacDonald MGelhaus S LKofler JSweet R A - Population stratification based on gut microbiota composition has revealed several enterotypes in humans and animals, providing valuable tools for studying the gut microbiota landscape, which is crucial for animal health and production. However, knowledge about rumen enterotype identification in sheep, its influencing factors, and its association with growth performance and host genetics remains limited. Here, we investigated host genetic effects and phenotypic landscapes of rumen bacterial enterotypes in a large sheep population. Ruminal contents from 1150 healthy sheep were analyzed using 16S rRNA gene sequencing and genus-level clustering, complemented by extensive phenotypic data covering 47 traits spanning growth, feed efficiency, meat yield, and ruminal fermentation, along with whole-genome resequencing data. We identified two distinct enterotypes: Enterotype 1 (E1), a mixture of multiple genera, and Enterotype 2 (E2), dominated by . E2 sheep exhibit superior growth and meat production performance, but lower feed efficiency and increased fat deposition. Two-part beta-regression models and co-occurrence network analyses revealed the extensive impact of enterotypes on microbial community structure, with E1 displaying a higher frequency of unique bacterial interactions. The estimated heritability of the enterotype was 0.47, and a GWAS identified five key genetic markers associated with rumen enterotype, localized to two candidate genes: and . These markers significantly influence 58 ruminal bacterial genera, including key taxa and driving genus. Overall, our data provide new insights into sheep rumen-enterotype characteristics, contributing to a better understanding of microbial interactions that are crucial for improving ruminant growth performance. - Source: PubMed
Publication date: 2025/09/17
Zhang YukunLi FadiZhang XiaoxueZhang DeyinWang Weimin - Chronic kidney disease (CKD) is highly prevalent among individuals with abnormal glucose metabolism. However, limited research has specifically investigated CKD-associated proteins within this high-risk population. To address this gap, our study aimed to identify proteins associated with CKD in participants with abnormal glucose metabolism, potentially informing early detection and targeted therapeutic strategies. - Source: PubMed
Publication date: 2025/09/09
Li NingLiu JingyangWu GuanghengZhang JieLiu LongZheng ManqiLi HaibinLi ChangweiWen YaluJi JianguangYu YangZhao KunZheng Deqiang - Based on the principles of Predictive, Preventive, and Personalized Medicine (PPPM), this study aimed to identify ferroptosis-related genes associated with multiple sclerosis (MS) and to explore the underlying mechanisms through genetic approaches. - Source: PubMed
Publication date: 2025/08/14
Xiong YaoYang DaifengCai Shanshan