Ask about this productRelated genes to: OSGEP antibody
- Gene:
- OSGEP NIH gene
- Name:
- O-sialoglycoprotein endopeptidase
- Previous symbol:
- -
- Synonyms:
- PRSMG1, GCPL1, OSGEP1, KAE1, TCS3
- Chromosome:
- 14q11.2
- Locus Type:
- gene with protein product
- Date approved:
- 2002-01-23
- Date modifiied:
- 2018-11-22
- Gene:
- OSGEPL1 NIH gene
- Name:
- O-sialoglycoprotein endopeptidase like 1
- Previous symbol:
- -
- Synonyms:
- Qri7, OSGEPL
- Chromosome:
- 2q32.2
- Locus Type:
- gene with protein product
- Date approved:
- 2003-09-03
- Date modifiied:
- 2016-10-05
Related products to: OSGEP antibody
Related articles to: OSGEP antibody
- N6-Threonylcarbamoyladenosine (tA) modification irregularities and their associated enzymes genes (OSGEP, OSGEPL1, TPRKB, GON7, TP53RK, YRDC, and LAGE3) are linked to various malignancies development, including Hepatocellular Carcinoma (HCC), yet the specific mechanisms remain obscure. This gap in knowledge is significant, as understanding the mechanisms of tA modification could reveal new insights into HCC pathogenesis and potentially identify novel therapeutic targets. - Source: PubMed
Publication date: 2025/03/16
Mui SintimShi JuanyiWen KaiYan YongcongLi HuomingWang WeidongZhou ZhenyuXiao Zhiyu - Recently, the presence of a complete five subunit Kinase, Endopeptidase and Other Proteins of small Size (KEOPS) complex was confirmed in humans. The highly conserved KEOPS protein complex has established roles in tRNA modification, protein translation and telomere homeostasis in yeast, but little is known about KEOPS mRNA expression and function in human brain and disease. Here, we characterise KEOPS expression in post-mortem tissue from subjects diagnosed with major depression (MDD) and schizophrenia and assess whether KEOPS is associated with telomere length dysregulation in neuropsychiatric disorders. - Source: PubMed
Publication date: 2020/09/29
Abel Mackenzie EZhang XiaoluAsah Sophie MWolfinger AlyssaMcCullumsmith Robert EO'Donovan Sinead M