Ask about this productRelated genes to: ACBD7 antibody
- Gene:
- ACBD7 NIH gene
- Name:
- acyl-CoA binding domain containing 7
- Previous symbol:
- -
- Synonyms:
- FLJ38219, bA455B2.2
- Chromosome:
- 10p13
- Locus Type:
- gene with protein product
- Date approved:
- 2004-05-27
- Date modifiied:
- 2019-03-21
Related products to: ACBD7 antibody
Related articles to: ACBD7 antibody
- Altered lipid metabolism is increasingly recognized as a driver of tumor progression, yet its specific role in thyroid cancer remains unclear. - Source: PubMed
Publication date: 2026/05/17
Wang TianzeNan BoyuanSa QilaXu NingZhang Wei - We sequenced and assembled using multiple long-read sequencing technologies the genomes of chimpanzee, bonobo, gorilla, orangutan, gibbon, macaque, owl monkey, and marmoset. We identified 1,338,997 lineage-specific fixed structural variants (SVs) disrupting 1,561 protein-coding genes and 136,932 regulatory elements, including the most complete set of human-specific fixed differences. We estimate that 819.47 Mbp or ∼27% of the genome has been affected by SVs across primate evolution. We identify 1,607 structurally divergent regions wherein recurrent structural variation contributes to creating SV hotspots where genes are recurrently lost (e.g., CARD, C4, and OLAH gene families) and additional lineage-specific genes are generated (e.g., CKAP2, VPS36, ACBD7, and NEK5 paralogs), becoming targets of rapid chromosomal diversification and positive selection (e.g., RGPD gene family). High-fidelity long-read sequencing has made these dynamic regions of the genome accessible for sequence-level analyses within and between primate species. - Source: PubMed
Publication date: 2024/02/29
Mao YafeiHarvey William TPorubsky DavidMunson Katherine MHoekzema KendraLewis Alexandra PAudano Peter ARozanski AllisonYang XiangyuZhang ShilongYoo DongAhnGordon David SFair TylerWei XiaoxiLogsdon Glennis AHaukness MarinaDishuck Philip CJeong HyeonsooDel Rosario RicardoBauer Vanessa LFattor Will TWilkerson Gregory KMao YuxiangShi YongyongSun QiangLu QingPaten BenedictBakken Trygve EPollen Alex AFeng GuopingSawyer Sara LWarren Wesley CCarbone LuciaEichler Evan E - To study the diagnostic value of mRNA expression in urinary exocrine body in bladder cancer. - Source: PubMed
Publication date: 2024/02/23
Wang XinyingSong DianbinZhu BaoxingJin YangCai CaisenWang Zhiyong - Anorexia nervosa (AN) is a severe psychiatric disorder characterized by an intense fear of gaining weight, a relentless pursuit of thinness, and a distorted body image. Recent research highlights the substantial contribution of genetics to AN's etiology, with genes like BDNF, SLC6A4, and DRD2 implicated. However, a comprehensive genetic test for AN diagnosis is lacking. This study aims to elucidate the biological foundations of AN, examining variants in genes associated with syndromic forms, rare variants in AN patients, and candidate genes from GWAS studies, murine models, or established molecular pathways. - Source: PubMed
Donato KMedori M CMacchia ACecchin SCeccarini M RBeccari TGatta VStuppia LBenfatti VDalla Ragione LMicheletti P Chiurazzi CDhuli KMadeo GBonetti GMarceddu GBertelli M - The epigenetic regulation mechanism of porcine skeletal muscle development relies on the openness of chromatin and is also precisely regulated by transcriptional machinery. However, fewer studies have exploited the temporal changes in gene expression and the landscape of accessible chromatin to reveal the underlying molecular mechanisms controlling muscle development. To address this, skeletal muscle biopsy samples were taken from Landrace pigs at days 0 (D0), 60 (D60), 120 (D120), and 180 (D180) after birth and were then analyzed using RNA-seq and ATAC-seq. The RNA-seq analysis identified 8554 effective differential genes, among which , and were identified as key genes related to the development of porcine skeletal muscle. Some potential cis-regulatory elements identified by ATAC-seq analysis contain binding sites for many transcription factors, including SP1 and EGR1, which are also the predicted transcription factors regulating the expression of genes. Moreover, the omics analyses revealed regulatory regions that become ectopically active after birth during porcine skeletal muscle development after birth and identified 151,245, 53,435, 30,494, and 40,911 peaks. The enriched functional elements are related to the cell cycle, muscle development, and lipid metabolism. In summary, comprehensive high-resolution gene expression maps were developed for the transcriptome and accessible chromatin during postnatal skeletal muscle development in pigs. - Source: PubMed
Publication date: 2023/03/29
Feng LingliSi JingleiYue JingweiZhao MingweiQi WenjingZhu SiranMo JiayuanWang LixianLan GanqiuLiang Jing