Ask about this productRelated genes to: HERC6 antibody
- Gene:
- HERC6 NIH gene
- Name:
- HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
- Previous symbol:
- -
- Synonyms:
- FLJ20637
- Chromosome:
- 4q22.1
- Locus Type:
- gene with protein product
- Date approved:
- 2004-06-03
- Date modifiied:
- 2016-10-05
Related products to: HERC6 antibody
Related articles to: HERC6 antibody
- - Source: PubMed
Publication date: 2026/04/22
Wei XiaoquanWang ShuhuiPeng WenkunHang YangYang QianyueSun ShuningMeng DefangNie MinYao GenhongSun Lingyun - We constructed a gene coexpression network to uncover central key genes related to Sjögren's disease (SjD), and investigated the clinical significance of bone marrow stromal antigen 2 (BST2) in SjD. - Source: PubMed
Publication date: 2026/04/09
Ren TianZhou XinZhou EryeLiu CuipingWu JianChang XinChen Weichang - Whole-genome sequencing (WGS) is a powerful tool for uncovering genome-wide variation, identifying selection signatures, and guiding genetic improvement in livestock. Royal White (RW) and White Dorper (WD) sheep are economically important meat-type hair breeds in the U.S., yet their genomic architecture remains poorly characterized. In this study, WGS was performed on 20 ewes ( = 11 RW, = 9 WD) to identify and annotate SNPs and small insertions and deletions (indels). Functional annotation, gene enrichment, population structure, and selective sweep analysis were also performed. Selective sweep analysis was conducted by integrating the fixation index (F), nucleotide diversity (π), and Tajima's D to identify candidate regions under putative recent positive selection. A total of 21,957,139 SNPs and 2,866,600 indels were identified in RW sheep, whereas 18,641,789 SNPs and 2,397,368 indels were identified in WD sheep. In RW sheep, candidate genes under selection were associated with health and parasite resistance (, , ) and growth traits (). In WD sheep, selective sweep regions included genes linked to immune response and parasite resistance (), body weight (), and reproduction (). These findings were supported by sheep-specific quantitative trait loci (QTL) annotations and previously reported SNP-trait associations. This study provides the first WGS-based genomic comparison between RW and WD sheep, establishing a foundation for future genetic improvement, including targeted selection for enhanced immune function, disease resistance, and other economically important traits in these breeds. - Source: PubMed
Publication date: 2026/03/05
Liao MingsiKravitz AmandaHaak David CSriranganathan NammalwarCockrum Rebecca R - Sesquiterpenoids and their derivatives have exhibited promising inhibitory effects against various types of cancers. However, the precise molecular targets and their interplay with the tumor microenvironment (TME) remain elusive. - Source: PubMed
Publication date: 2026/02/13
Li XiaobingZeng XueLi XuemeiLiu YongshengTang JunlingZhang LiWei LiminMao Jingxin - Steroid-induced osteonecrosis of the femoral head (SONFH) lacks effective early-stage interventions, and its systemic drivers remain incompletely defined. Luteolin (Lut) is reported to be protective, but the in vivo mechanism is unclear. We investigated whether Lut acts through a gut microbiota–metabolite–innate immunity axis in SONFH. - Source: PubMed
Publication date: 2026/02/06
Li TongLi YifeiGao JiaxiangMa RuichenPeng YueZhang QidongChen YingzhiWang Weiguo