CD38 antibody (Azide Free)
- Known as:
- CD38 (anti-) (Azide Free)
- Catalog number:
- 10r-cd38cmsp
- Product Quantity:
- USD
- Category:
- -
- Supplier:
- Fitzgerald industries international
- Gene target:
- CD38 antibody (Azide Free)
Related genes to: CD38 antibody (Azide Free)
- Gene:
- CD38 NIH gene
- Name:
- CD38 molecule
- Previous symbol:
- -
- Synonyms:
- -
- Chromosome:
- 4p15.32
- Locus Type:
- gene with protein product
- Date approved:
- 1986-01-01
- Date modifiied:
- 2014-11-18
Related products to: CD38 antibody (Azide Free)
Related articles to: CD38 antibody (Azide Free)
- To evaluate anti-CD38 antibody candidates for their ability to bind to DTT-treated CD38 and red blood cells (RBCs). - Source: PubMed
Publication date: 2026/09/02
Zeretzke AnjaTrummer PhilippHabicht Cora PSchneeweiss Clemens - To investigate whether residual activated T helper 17 (Th17) cells during inactive disease or low disease activity (LDA) in radiographic axial spondyloarthritis (r-axSpA) are associated with subsequent disease instability. - Source: PubMed
Publication date: 2026/09/01
Chan Kwon OhKim Lark KyunPark Min-Chan - Still's disease (SD) is an autoinflammatory disorder characterized by remarkably high IL-18 levels. Increasing evidence suggests that adaptive immunity also contributes to its pathogenesis, particularly in refractory courses. Macrophage activation syndrome (MAS), one of SD's most severe complications, is associated with further IL-18 elevation and expansion of CD38HLA-DRCD8 T cells. However, whether and when this population emerges during SD remains unknown. We therefore examined CD38HLA-DRCD8 T cells across disease stages. - Source: PubMed
Publication date: 2026/09/01
Rogani GretaErkens Remco G ABodelón AlejandraMocking Tim RPutmans Marein T MHuijsmans Freya M C HSijbers Lyanne J P MDe Ligt Aafke MVan Haaren Maurice J HScholman Rianne CDautzenberg Noël M MMeesters-Ensing Joyce IRossano MartinaPorretti LauraNierkens StefanMinoia Francesca SVastert Sebastian Jvan Loosdregt Jorg - Short-term mycophenolic acid (MPA) withdrawal is common in kidney transplant recipients with severe infections and was extended during the COVID-19 pandemic to improve vaccine immunogenicity, yet its effects on immune cell dynamics remain mechanistically understudied. - Source: PubMed
Publication date: 2026/08/17
Goerlich NinaStich MaximilianGünter ManinaKühn TessaSpeer ClaudiusSchaier MatthiasTönshoff BurkhardZeier MartinMorath ChristianFribourg MiguelAutenrieth Stella EBenning Louise - Osteogenic differentiation requires sophisticated mitochondrial adaptation to meet bioenergetic demands, yet regulatory checkpoints governing this organelle reorganization remain poorly defined. Through single-cell RNA sequencing reanalysis and metabolic intervention, this study unveils a non-canonical signaling role for PFKM, traditionally recognized solely as a glycolytic enzyme, in orchestrating mitochondrial remodeling during bone formation. Beyond its established metabolic function, Pfkm suppression triggers distinctive donut-shaped mitochondria through a novel signaling cascade. Mechanistically, Pfkm knockdown expands mitochondria-endoplasmic reticulum contacts (MERCs), facilitating mitochondrial calcium influx. Concomitantly, elevated CD38 suppresses protein kinase A (PKA) activity, inducing DRP1 dephosphorylation at Serine 656. This signaling integration promotes DRP1 mitochondrial translocation, driving the characteristic donut architecture. This structural transformation initiates comprehensive mitochondrial quality control (MQC) encompassing enhanced biogenesis, selective mitophagy, and mitochondrial-derived vesicles (MDVs) secretion, collectively optimizing the osteogenic microenvironment and cellular mineralization capacity. In vivo validation demonstrates that AAV-mediated Pfkm knockdown accelerates bone repair in rat calvarial and femoral defect models. This work establishes PFKM as a dual-function regulator bridging metabolism and mitochondrial signaling, offering a potent therapeutic avenue for bone regeneration. - Source: PubMed
Publication date: 2026/08/31
Huang NengwenLi YangLu JieXing YifengChen WeipingChen KaidiZheng GeyuanHu PengyuanHe KaixunLin HanyuYuan WenxiuZhou YuweiXue ZhenzhuLin JunjinLi WenZhang SihuiOu YanjingChen Jiang