Ask about this productRelated genes to: GDF3 antibody
- Gene:
- GDF3 NIH gene
- Name:
- growth differentiation factor 3
- Previous symbol:
- -
- Synonyms:
- -
- Chromosome:
- 12p13.31
- Locus Type:
- gene with protein product
- Date approved:
- 1999-04-23
- Date modifiied:
- 2016-10-05
Related products to: GDF3 antibody
Related articles to: GDF3 antibody
- Growth differentiation factor 3 (GDF3), a TGFβ superfamily cytokine, has been linked to visceral adipose proliferation and adiposity in animal studies. However, the relationship between circulating GDF3 levels and visceral adiposity in humans remains unclear. This study aimed to assess the potential of serum GDF3 as a biomarker for visceral obesity. - Source: PubMed
Publication date: 2026/08/13
Li ZhaozhiLi JiaoyangOuyang YunJiang LiyanLiao ZhezhenRan LiYang FeiXiao XinhuaWang Yadi - - Source: PubMed
Publication date: 2026/07/18
Xia FangqiHu YaqiWang YaqiXue MengzhenZhu LeiqiLi YuanyangZhang YifanWang ShuwenWang RuiYuan QiHe YuminYuan DingZhang JihongYuan Chengfu - Prostate cancer is a prevalent disease with diverse tumor characteristics that complicate treatment. The integration of spatial patterns from prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT), pathology and expanding genomic data represents a groundbreaking advancement in histo-imaging genomics. The aim of this study was to elucidate the internetwork mapping between genetic biomarkers and PSMA PET/CT imaging in prostate cancer patients. - Source: PubMed
Publication date: 2026/07/04
Qu LiliLi KaiyueWang MuwenXiao YadiJin XinZhou HangYuan LujieLi YuekaiWang ShiweiLi RuiHacker MarcusLi XinLi Xiang - - Source: PubMed
Publication date: 2026/06/28
Xia FangqiHu YaqiWang YaqiXue MengzhenZhu LeiqiLi YuanyangZhang YifanWang ShuwenWang RuiYuan QiHe YuminYuan DingZhang JihongYuan Chengfu - The coordination of cell migration and proliferation is essential for embryogenesis and tissue homeostasis. However, the classical gradient signaling model is insufficient to explain how stable mitogenic signaling is maintained within migratory cells. Here, we reveal that primordial germ cells (PGCs) in zebrafish employ migrasomes-vesicular organelles formed during migration-to couple their proliferation with migration, ensuring germline expansion. Migrasomes, generated at retraction fibers via tspan7-dependent biogenesis, deliver the growth factor GDF3 specifically to neighboring PGCs through contact-dependent interactions. GDF3 activates the TGF-β receptor acvr1ba, driving proliferation in a spatiotemporally restricted manner. This homocrine signaling mechanism allows migrating PGCs to autonomously sustain proliferation, circumventing signal dilution in embryonic environments. This work uncovers migrasomes as a bridge linking migration and proliferation, with implications for understanding collective cell behaviors in development and disease. - Source: PubMed
Publication date: 2026/04/10
Liu BoqiJiang ZhengSong WenhaoZhai ZhaochengLi YaqiZhang WeiyingMeng AnmingYu Li