Ask about this productRelated genes to: CKMM antibody
- Gene:
- CKM NIH gene
- Name:
- creatine kinase, M-type
- Previous symbol:
- CKMM
- Synonyms:
- -
- Chromosome:
- 19q13.32
- Locus Type:
- gene with protein product
- Date approved:
- 2001-06-22
- Date modifiied:
- 2016-02-10
Related products to: CKMM antibody
Related articles to: CKMM antibody
- Pancreatic resection is a profound physiologic stress test. Traditional risk assessment often focuses on procedure-specific technical failures, yet postoperative recovery depends heavily on a patient's systemic physiologic reserve. We evaluated the association between the American Heart Association's Cardiovascular-Kidney-Metabolic (CKM) syndrome framework and outcomes following pancreatic resection. - Source: PubMed
Publication date: 2026/08/20
Elgabsi MiriAbumouch IsisZilbermints VeacheslavBaker Fadi AbuHazzan RawiMahamid Ahmad - Cardiovascular-kidney-metabolic (CKM) syndrome confers elevated mortality risk, but whether dietary ketogenic ratio (KDR) is associated with mortality in this population remains unclear. We examined the association of KDR with mortality in adults with CKM syndrome and whether it persisted after accounting for broader diet-quality metrics. - Source: PubMed
Publication date: 2026/08/05
Guo HuiWang LeiXiao Fangping - ObjectiveCardiovascular-Kidney-Metabolic (CKM) syndrome, characterized by interconnected metabolic, cardiovascular, and renal dysfunctions, is linked to chronic low-grade inflammation, a key driver of comorbidities like chronic obstructive pulmonary disease (COPD). C-reactive protein (CRP), a sensitive inflammation biomarker, may predict COPD risk in CKM stages 0-3 (no overt CVD), but longitudinal patterns of CRP remain underexplored.MethodsIn this prospective cohort study, we included 4,887 participants aged ≥45 years with CKM stages 0-3 and without prior COPD from the China Health and Retirement Longitudinal Study (CHARLS). CRP was measured in 2012 and 2015. Longitudinal change patterns were identified using k-means clustering. Cumulative CRP exposure (cumCRP) was calculated as the area under the curve. Incident COPD was defined based on self-reported physician diagnosis plus objective evidence of airflow limitation (peak expiratory flow <80% predicted) in 2018. Multivariable logistic regression was used to assess associations.ResultsFour CRP change patterns were identified: stable low-risk (Class 1), rapidly increasing (Class 2), significant improvement (Class 3), and persistently high-risk (Class 4). Compared to Class 1, Class 4 was associated with a 69% higher COPD risk (adjusted OR=1.69, 95% CI: 1.28-2.23). High cumCRP (tertile 3 vs. 1) increased COPD risk by 65% (OR=1.65, 95% CI: 1.32-2.08). The association was stronger in advanced CKM stages 0-3 (no overt CVD), particularly Stage 3.ConclusionsLongitudinal CRP change patterns and cumulative CRP exposure are independently associated with incident COPD in individuals with CKM stages 0-3 (no overt CVD). Persistently elevated or rapidly increasing CRP may help identify high-risk individuals for targeted monitoring and early intervention. - Source: PubMed
Publication date: 2026/08/20
Liu YunyuGong JunZhang JianTan JuntaoTan Chao - In 2023, the American Heart Association established the cardiovascular-kidney-metabolic (CKM) syndrome and defined its different stages. Here, we analyzed the prospective associations of CKM stages with mortality outcomes and how CKM syndrome progresses over time. - Source: PubMed
Publication date: 2026/08/20
Li LanlanLui David Tak-WaiFong Carol Ho-YiMak Jimmy Ho-CheungCheung Chloe Yu-YanXu AiminTan Kathryn Choon-BengTse Hung-FatWoo JeanLam Tai-HingWoo Yu-ChoCheung Bernard Man-YungLam Karen Siu-LingLee Chi-Ho - Frailty shares common pathophysiological mechanisms with cardiovascular-kidney-metabolic (CKM) syndrome and may contribute to cardiovascular risk. However, evidence regarding the associations of physical frailty and frailty index with cardiovascular outcomes in individuals with CKM stages 0-3 remains limited. - Source: PubMed
Publication date: 2026/08/05
Wang JunhongZhao YingMa Zongzong