c_Jun (Phospho_Thr91) Antibody
- Known as:
- c_Jun (Phospho_Thr91) Antibody
- Catalog number:
- E011021-1
- Product Quantity:
- 50ug
- Category:
- Antibodies
- Supplier:
- EnoGene
- Gene target:
- c_Jun (Phospho_Thr91) Antibody
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Related articles to: c_Jun (Phospho_Thr91) Antibody
- Asthma is a common pediatric disease of the airways. Obesity among children increases the risk of asthma and is associated with a unique non-allergic asthma phenotype that is highly symptomatic and often unresponsive to conventional drugs. However, the mechanisms linking obesity with incident asthma, more frequent and severe symptoms, and resistance to conventional drugs remain unknown. Excess fat on the chest wall and abdomen forces children with obesity to breathe at lower lung volumes where small airway dysfunction is more likely to occur and where the normal length-tension relationship of the diaphragm is suboptimal; this leads to altered breathing mechanics and inspiratory muscle fatigue, which could lead to exertional dyspnea. While inspiratory training (IT) increases inspiratory muscle strength and endurance, improves exercise tolerance, and reduces exertional dyspnea, most research has focused on adults. The Mechanistic Study of Inspiratory Training in Childhood Asthma (MICA) study is designed with 2 objectives: (1) compare measures of small airway dysfunction and inspiratory muscle functioning between obese ( = 38) versus non-obese ( = 38) 6-17-year-olds with asthma and (2) measure small airway disease and inspiratory muscle function in response to 8 weeks of inspiratory training. We will also assess physical fitness, activity levels, and exertional dyspnea. This study will lay the foundation for dose selection and optimal target population of a larger trial. IT could represent a novel therapy to help children with asthma and obesity improve quality of life through reduced exertional symptoms and enhanced activity levels. - Source: PubMed
Publication date: 2026/04/13
Bhammar Dharini MJones Harrison NAli-Dinar Tarig MOrenduff Melissa CDavalos AngelGoldstein Benjamin ALang Jason E - Lumbar disc herniation (LDH) causes low back pain and lower-limb neurological symptoms. Conservative and surgical treatments have similar outcomes and recurrence rates within two years. Anti-inflammatory drugs or opioids reduce inflammation but are unsuitable for long-term use. Physiotherapy improves mobility and function, but has limited evidence for reversing disc herniation. Platelet-rich plasma (PRP) is emerging as a regenerative therapy for LDH. Combining ultrasound-guided PRP with McKenzie therapy may enhance disc repositioning, tissue repair, and sustained recovery. This pragmatic trial evaluates whether adding an ultrasound-guided PRP injection pathway to standard McKenzie therapy improves clinical and neurophysiological outcomes compared with McKenzie therapy alone in a low-resource setting. In the absence of a sham control, it assesses real-world effectiveness rather than the isolated biological efficacy of PRP. - Source: PubMed
Publication date: 2026/04/15
Islam RayhanUdoy Mahmudul HaqueIslam Md ZahirulSayeed Md AbuKabir FerozHossain Md ZahidJahan SharmilaRahman EhsanurHossain Mohammad AnwarHossain K M Amran - Congenital giant melanocytic nevus (GCMN) is a rare congenital lesion associated with potential risks of malignant transformation and neurocutaneous melanosis, which severely impacts patients' appearance and psychological health. Early intervention is crucial, and skin tissue expansion has been recognized as a primary surgical approach. This study aims to explore the feasibility and clinical efficacy of early treatment of GCMN using skin tissue expansion. - Source: PubMed
Publication date: 2026/03/14
Jiaqi ZhangCheng ChenJun GeChen ChenJinming ZhangWeiqiang Liang - To address gender disparities in career advancement in academic emergency medicine, we sought to identify specific and actionable approaches that an academic department could develop or enhance to create a sustainable pathway for advancement of women in academic and leadership roles. - Source: PubMed
Publication date: 2026/04/17
Zachrison Kori SKapanadze MariamJames DaraAl Jalbout NourCash Rebecca EChua Wee-JhongDobiesz ValerieEgan Daniel JNelson Erica LPham PhuongTemin ElizabethSamuels-Kalow Margaret E - - Source: PubMed
Publication date: 2026/04/17
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