Minor Skin Procedures
- Known as:
- Minor Skin Procedures
- Catalog number:
- KMMS147
- Category:
- -
- Supplier:
- Kemaj
- Gene target:
- Minor Skin Procedures
Related genes to: Minor Skin Procedures
- Gene:
- CCL27 NIH gene
- Name:
- C-C motif chemokine ligand 27
- Previous symbol:
- SCYA27
- Synonyms:
- ALP, ILC, CTACK, skinkine, ESkine, PESKY, CTAK
- Chromosome:
- 9p13.3
- Locus Type:
- gene with protein product
- Date approved:
- 1999-07-30
- Date modifiied:
- 2016-10-05
Related products to: Minor Skin Procedures
(NVDP)4 peptide (minor repeat-sequence peptide of the P. falciparum circumsporozoite protein, CSP) conjugated with BSA(NVDP)4 peptide (minor repeat-sequence peptide of the P. falciparum circumsporozoite protein, CSP) control blocking peptide*M_Broth USE For detecting Salmonellae in foods and feeds by the accelerated enrichment serology procedures.1,2,3,4-tetrahydro-1,2-dimethyl-4,8-isoquinolinediol
(Minor Product) CAS: 102830-20-6 Formula: C11H15NO23 kinds of surface markers represent minor operation areasA panel of 3% reagent red blood cells for quality control of anti_human globulin procedures (Coombs control cells)A-431 Cell Slide (Human (85 yrs, Female) skin epidermoid carcinoma) (5 slides pk)Adult Normal Skin LysateAdvanced Skin and muscle suture practice moduleAge grouped female skin tissue array, 12 cases_24 cores, replaced by SK244Age grouped female skin tissue array, 12 cases_24 cores, replaced by SK244; ihc Anti-Actin confirmedAge grouped female skin tissue array, 12 cases_24 cores, replacing SK243Age grouped female skin tissue array, 12 cases_24 cores, replacing SK243Age grouped female skin tissue array, 12 cases_24 cores, replacing SK243; ihc Anti-Actin confirmedAge grouped female skin tissue array, 12 cases_24 cores, replacing SK244 Related articles to: Minor Skin Procedures
- Major depressive disorder (MDD) is a prevalent mental illness with a significant disease burden. It is characterized by immune-inflammatory dysregulation. - Source: PubMed
Chen TangcongLuo YueyangNiu MengqiLi JingLi MengdieZhang YingqianMaes Michael - While circadian rhythms are critical regulators of cardiovascular physiopathology, their role in Takotsubo Syndrome (TTS) remains poorly understood. This study aimed to investigate the influence of time-of-day on cardiac hypertrophy and inflammation in a mouse model of TTS induced by isoproterenol (ISO) administration. Female mice were injected with saline (Sal) or ISO at the beginning of the light (ZT0) or dark phase (ZT12). Our data show that mice treated with ISO at ZT12 developed more prominent cardiac hypertrophy and exhibited worse cardiomyocyte calcium handling. This was accompanied by an enhanced accumulation of leukocytes in the hearts of ISO/ZT12 compared with ISO/ZT0 mice. Flow cytometry analysis revealed an exacerbation in the number CD64Ly6CCCR2 monocytes/macrophages at ZT12 indicating a time-of-day influence on the inflammatory response following ISO administration. Of note, these differences were not secondary to differences in initial tissue injury as assessed by Evans Blue uptake by necrotic cells. However, cardiac expression of Ccl2/7 was significantly higher in the hearts of ISO/ZT12 in comparison to ISO/ZT0, suggesting the involvement of the CCL2/CCR2 signaling axis in the enhanced recruitment of monocytes. Finally, pharmacological and genetic strategies used to prevent CCR2-dependent recruitment of monocytes ameliorated the cardiac hypertrophy induced by ISO at ZT12, indicating that the CCL2/CCR2 signaling axis is crucial to the temporal dependent effects of ISO. Taken together, our data show a previously unrecognized role of the time-of-day on cardiac inflammation following adrenergic overload. - Source: PubMed
Publication date: 2026/08/01
Sanches BrunoSouza-Neto FernandoPires Giovane L CAbramo HenriqueEliezeck MarcosScalzo Sergio ASilva Nikolas SantosAmaral Flávio Almeidavan Berlo Jop HGuatimosim SilviaRocha-Resende Cibele - Atopic dermatitis (AD) is a chronic skin disorder driven by Th2 immune dysregulation, persistent inflammation, and epidermal barrier defects. Oxidative stress acts as a major upstream factor in this process, amplifying inflammatory signals and worsening disease severity. While current treatments relieve acute symptoms, long-term application is often constrained by side effects and poor barrier restoration, pointing to a need for safer, multifaceted alternatives. Here, we formulated a complex of extract (TJE) and GHK-Cu (Glycyl-L-histidyl-L-lysine copper(II)) complex and examined its anti-atopic and skin-regenerative properties using a TNF-α (Tumor necrosis factor-α)/IFN-γ (Interferon-γ)-stimulated HaCaT cell model. TJE decreased the expression of AD-related chemokines (TARC(Thymus and activation-regulated chemokine (CCL17)) and CTACK(Cutaneous T-cell-attracting chemokine (CCL27)) as well as IgE production, confirming the suppression of Th2-driven inflammation. An optimized 6:4 ratio (TJE:GHK-Cu) yielded the highest efficacy compared to individual treatments, indicating a synergistic interaction. TJE-GHK-Cu complex suppressed the transcription of key Th2 cytokines (IL-4, IL-5, IL-10, and IL-13) and promoted keratinocyte migration during wound healing assays. The formulation also displayed strong radical scavenging activity without compromising cell viability. These results demonstrate that the TJE-GHK-Cu complex provides simultaneous anti-inflammatory, antioxidant, and regenerative benefits, presenting a formulation warranting further investigation for managing AD. - Source: PubMed
Publication date: 2026/06/29
Jeon SoojinMaeng JihyeLee JiwonKim Young-MinNam Gaewon - Psoriasis patients were 4- 5 times more likely to have S. aureus colonize their skin. Psoriasis is caused by staphylococcal infection-induced keratinocyte death, which is maintained by elevated cytokine production of TNF-α and IFN-γ. The study sought to determine the association between the influence of gene expression of certain genes in psoriasis infections in the presence of S. aureus and their effect in Skin Cutaneous Melanoma infections. GEO with accession number (GSE207390) was used to acquire the data. The microarray test was used to perform this investigation. Six sets of keratinocytes, IL-17A, and TNF-α were cultivated together. Several kinds of bioinformatics tools were employed to fulfill the study's objective. Gene hub analysis of 34284 genes was scanned. Six genes demonstrated high expression rates were expressed during the metastatic stage: , , , , , and . and had the highest levels of expression. The expression of the gene rose in response to sun exposure, but the expression of the other genes remained same. The existence of cytokine groups with in keratinocytes influences the expression difference compared to the other groups. This work adds to our understanding of the molecular alterations that occur in the epidermis of psoriasis patients, as well as their relationship to comorbidities. - Source: PubMed
Ali-Adel DawoodMawj-Saddam Zabn - Atopic dermatitis (AD) is a prevalent inflammatory skin disease and a major source of disease burden in children. Biomarker studies in childhood AD span genetic, immune, microbial and metabolic domains, but prior reviews have often focused on single molecular layers, specific sample sites or clinical classification. As a result, the field lacks an integrated, systems-level synthesis that compares and contextualizes biomarkers across domains while clearly distinguishing evidence strength. The rapid growth of literature in this field also poses practical challenges for traditional manual review workflows. - Source: PubMed
Publication date: 2026/07/04
Lee Jia WeiLoo Evelyn X LChong Samuel SBan Kenneth H KLee Caroline G