STAT3 Antibody
- Known as:
- STAT3 Antibody
- Catalog number:
- XW-8107
- Product Quantity:
- 0.05 mg
- Category:
- -
- Supplier:
- Prosci
- Gene target:
- STAT3 Antibody
Related genes to: STAT3 Antibody
- Gene:
- STAT3 NIH gene
- Name:
- signal transducer and activator of transcription 3
- Previous symbol:
- -
- Synonyms:
- APRF
- Chromosome:
- 17q21.2
- Locus Type:
- gene with protein product
- Date approved:
- 1995-11-08
- Date modifiied:
- 2019-04-23
Related products to: STAT3 Antibody
Related articles to: STAT3 Antibody
- Fracture healing is a complex regenerative process requiring coordinated interactions among vascular, skeletal, and neural systems. Angiogenesis is a critical rate-limiting step that regulates oxygen delivery, inflammatory resolution, and osteogenic cell recruitment within the fracture microenvironment. Huoxue Jiegu Compound Capsule (HXJGCC), a traditional Chinese medicine formulation, has demonstrated clinical efficacy in fracture management; however, its molecular mechanisms underlying fracture repair remain insufficiently elucidated. - Source: PubMed
Publication date: 2026/05/11
Lu WeisongPu BinWang DongTan ShixiangWu YingjieSun YangzhanLi MengzeXu Hegui - Monotherapy with photothermal therapy (PTT) hardly achieves durable and significant antitumor efficacy. To further improve the therapeutic effect against tumors, in this study, the chemotherapeutic agent thioridazine (THZ) was loaded into a gel network formed by the Schiff base cross-linking of amino-functionalized graphene quantum dots (NH-GQDs) and oxidized dextran. A pH-responsive injectable carbon dot composite hydrogel delivery system (NTD@Gel) with dual effects of photothermal therapy and chemotherapy was thereby constructed. - Source: PubMed
Publication date: 2026/05/19
Wu YunchaoXu XinZhu ZhenDu FengyiZheng Guojun - To investigate the potential molecular mechanisms underlying the contribution of environmental bisphenol A (BPA) exposure to acne pathogenesis, with a specific focus on the PLA2G2A-arachidonic acid pathway. - Source: PubMed
Publication date: 2026/05/19
Xu WenQian ShutongGao QiTao XiaohuaXu Danfeng - ( ) infection is a major risk factor for gastric cancer, though the immune microenvironmental factors driving preneoplastic transformation remain unclear. In this study, single-cell RNA sequencing was used to characterize macrophage subsets and identify key genes associated with -induced gastric lesions. Molecular, cellular, and assays were conducted to determine the mechanisms regulating the expression of a disintegrin and metalloproteinase-like decysin 1 ( ) and its downstream effects. M2 macrophages were significantly enriched in -positive gastritis and metaplasia, and showed progressive increase in expression during lesion progression. promoted M2 polarization and induced transcription signal transducer and activator of transcription 3 (STAT3) binding to its promoter. Functionally, M2-derived ADAMDEC1 increased soluble epidermal growth factor levels, thereby activating the epidermal growth factor receptor (EGFR)-extracellular signal-regulated kinase 1/2 (ERK1/2) signaling pathway in epithelial cells, which led to upregulation of C-C motif chemokine ligand 20 (CCL20) expression, enhanced proliferation, and impaired genomic stability. The present study reveals a potential -driven oncogenic pathway involving the M2 macrophage-ADAMDEC1-EGF/EGFR/ERK axis, establishing ADAMDEC1 as a potential target for early intervention in -associated gastric cancer. - Source: PubMed
Publication date: 2026/05/25
Kan HaoxuanNiu GuoyangWang LuyaoZou YifanWan ZihanXu YihanYang HaojunLi BowenXu Zekuan - To investigate the protective effects of ultrafine powder (UXP) against lipopolysaccharide (LPS)-induced acute lung injury (ALI) in mice and the underlying mechanism. - Source: PubMed
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