IL12B Antibody
- Known as:
- IL12B Antibody
- Catalog number:
- XW-7803
- Product Quantity:
- 0.05 mg
- Category:
- -
- Supplier:
- Prosci
- Gene target:
- IL12B Antibody
Ask about this productRelated genes to: IL12B Antibody
- Gene:
- IL12B NIH gene
- Name:
- interleukin 12B
- Previous symbol:
- NKSF2
- Synonyms:
- CLMF, IL-12B, NKSF, CLMF2
- Chromosome:
- 5q33.3
- Locus Type:
- gene with protein product
- Date approved:
- 1991-08-08
- Date modifiied:
- 2019-04-23
Related products to: IL12B Antibody
Related articles to: IL12B Antibody
- Atopic dermatitis (AD) is a heterogeneous inflammatory skin disease with known ethnic disparities in clinical presentation and treatment response. However, molecular data, particularly for Hispanic patients, remain limited. - Source: PubMed
Publication date: 2026/04/25
Liu DanielDel Duca EsterBrunner PatrickAvallone GianlucaBeaziz JessicaMetukuru RagasrutiLin XinyiEstrada YerielLau MeganLargen JosephUngar BenjaminGuttman-Yassky Emma - Accurate biomarkers that reflect disease activity, severity, and molecular pathophysiology in multiple sclerosis (MS) remain an unmet diagnostic need. We compared the performance of the established biomarkers, neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP), with emerging candidates in CSF and serum. - Source: PubMed
Publication date: 2026/04/23
Oechtering JohannaSchaedelin Sabine AnnaMaleska Maceski AleksandraStein KerstinGenc NafiyeEinsiedler MaximilianBenkert PascalWillemse ElineDerfuss Tobias JFischer-Barnicol BettinaD'Souza MarcusRegeniter AxelHu WayneQureshi FerhanFinkener SebastianMueller StefanieHoepner RobertLalive Patrice HPot CarolineGobbi ClaudioZecca ChiaraRoth PatrickWiendl HeinzLünemann Jan DKappos LudwigGranziera CristinaLeppert DavidKuhle Jens - Bovine tuberculosis (bTB), caused by Mycobacterium bovis, remains a major zoonosis impacting livestock productivity and public health. To characterize species-specific immune responses and identify transcriptional biomarkers of infection, we quantified the expression of 45 immune-related genes in peripheral blood from naturally infected cattle and Mediterranean buffalo. Differential and multivariate analyses revealed distinct species- and state-specific transcriptional signatures. Sixteen genes were significantly modulated in cattle, with Canonical Discriminant Analysis (CDA) defining a promising diagnostic signature marked by upregulation of IFNG, CASP8, CASP1, and CD83, and downregulation of IL10, CXCR2, and MMP9. In buffaloes, 22 genes were differently expressed across the three clinical groups. The first canonical function (Can1), driven positively by IFNG and IL12B and negatively by MMP9 and TLR5, effectively separated healthy from infected and affected animals, while the second function (Can2) distinguished the affected status through marked upregulation of CXCL1 and IL6. The species-specific immune signatures uncovered underscore the importance of developing tailored biomarker panels for improved diagnosis and surveillance of bTB in different livestock species. - Source: PubMed
Publication date: 2026/04/16
Signorelli FedericaMarè CaterinaDe Matteis GiovannaGrandoni FrancescoOrrù LuigiLamontanara AntonellaSchiavo LorenaDonniacuo AnnaCerrone PasqualeSpoleto ClaudiaDe Carlo EsterinaGaliero GiorgioIovane GiuseppePaciello OrlandoMartucciello AlessandraNapolitano Francesco - SUMOylation, a type of posttranslational protein modification, is linked to numerous biological processes, including tumorigenesis, the immunological response, and DNA repair. Immune-related genes are crucial for immune monitoring and the formation of the tumor immunological microenvironment. The aim of this work was to create a survival prediction model that combines SUMOylation and immune-related gene expression to guide personalized treatment strategies for triple-negative breast cancer (TNBC) patients. - Source: PubMed
Publication date: 2026/04/15
Zou PengchengXu HongyanGao YangBai WeichaoZhao XinhanShao Shan - This study aims to elucidate the role of Enterococcusin the progression from inflammatory bowel disease to colorectal cancer (CRC), with a focus on identifying key metabolites and host genes regulated by Enterococcusand their influence on CRC development. - Source: PubMed
Publication date: 2026/03/30
Huang GangLiu JianiCheng ZhipengChen YixinChen KexinLiu WanLiu HancongXia XinhaoLu ManCui WenxiZhang QingqingYuan YiZhong FeiLiao Yiwen