C13orf12 Antibody
- Known as:
- C13orf12 Antibody
- Catalog number:
- XW-7772
- Product Quantity:
- 0.05 mg
- Category:
- -
- Supplier:
- Prosci
- Gene target:
- C13orf12 Antibody
Related genes to: C13orf12 Antibody
- Gene:
- POMP NIH gene
- Name:
- proteasome maturation protein
- Previous symbol:
- C13orf12
- Synonyms:
- HSPC014, UMP1
- Chromosome:
- 13q12.3
- Locus Type:
- gene with protein product
- Date approved:
- 2003-01-29
- Date modifiied:
- 2016-10-05
Related products to: C13orf12 Antibody
Related articles to: C13orf12 Antibody
- In recent years, artificial intelligence (AI) has ushered in a promising era in medicine, particularly in medical education. However, studies assessing the knowledge, attitudes, and practices related to AI among medical students in Vietnam remain limited. - Source: PubMed
Publication date: 2026/07/03
Bui Minh TienLe Ha MyLuong Thi Khanh HuyenVu Hoang AnhTran The AnhNgo Thi Phuong LinhBui Dieu LinhBui Thi HanNguyen Duy CuongNgo Thanh BinhNguyen Trung KienDao Thi Loi - Trimethylamine n-oxide (TMAO) is a plasma metabolite linked to adverse cardiometabolic health with complex regulation involving diet, sex, and host genetics. We explored the role of these factors in the genetic regulation of TMAO by performing a primary-level meta-analysis in 1,482 female and male Diversity Outbred (DO) mice from five distinct studies conducted in various regions of the United States. We identified a quantitative trait locus (QTL) associated with TMAO concentration at ~86 megabase pairs on mouse chromosome 12 with a highly significant LOD score of 67.67. Alleles at the chromosome 12 QTL inherited from the Cast/EiJ (CAST) and PWK/PhJ (PWK) mouse strains primarily drove the association with reduced TMAO concentrations. The chromosome 12 QTL remained significant in sex-stratified analyses and the mode of inheritance appeared additive; furthermore, the QTL was regulated by sex-by-genotype and sex-by-diet interactions. Using a CAST/EiJ X C57BL/6J F2 cross, positional candidates were prioritized by eQTL analysis. Further analysis in a study utilizing the eight DO founding strains identified that was differentially expressed in hepatic tissue from CAST mice, prompting investigation into its genetic regulation. demonstrated relevant - and -regulation and was significantly correlated with TMAO and hepatic However, no significant relationships between and TMAO were identified in mice inactivated for or with AAV overexpression of in the liver. Genes within the chromosome 12 QTL have synteny with humans and may translate to the genetic regulation of human plasma TMAO concentrations and atherosclerosis. - Source: PubMed
Publication date: 2026/06/24
Sutton Kristen JEvans Levi WGertz Erik RBudke DawsonHuda NazmulYam PhoebeKim MyungsukRutkowsky JenniferShih DianaHartiala JaanaPomp DanielLusis Aldons JAllayee HoomanBennett Brian J - Artificial intelligence (AI), especially generative AI and large language models, is increasingly influencing higher education and health professions training. However, there is still limited empirical evidence about what veterinary students know about AI, how they use it, and how they perceive it. The aim of this study was to evaluate self-perceived AI-related knowledge, use, and attitudes among veterinary students in Spain and Portugal, and to analyze the influence of institutional context, prior AI training, and digital engagement. A cross-sectional survey was conducted during the 2023-2024 academic year with 340 undergraduate and postgraduate veterinary students from public and private institutions in Spain and Portugal. The questionnaire included sociodemographic questions and nine Likert-scale items assessing self-perceived AI knowledge, use, and attitudes. Composite scores were calculated and transformed using the Percentage of Maximum Possible (POMP) method (0-100 scale). Internal consistency of the instrument was high ( = 0.842; = 0.835). Data was analyzed using MANOVA, one-way ANOVA, independent samples t-tests, and Pearson correlation analyses. Significant differences were observed between institutions in self-perceived AI knowledge, use, and attitudes. Students who had received prior AI training showed higher self-perceived knowledge and use scores ( < 0.001) and more positive attitudes toward AI ( < 0.001). Although formal AI training was limited in many institutions, students with any type of prior exposure-self-directed, university-based, or external-reported greater engagement and felt more prepared to use AI tools. Daily social media use showed a small but statistically significant positive correlation with self-perceived AI knowledge and use (r = 0.115, = 0.034) and with positive attitudes (r = 0.157, = 0.004). Categorized analyses showed a gradual increase in AI-related outcomes with higher levels of digital engagement. Veterinary students in the Iberian Peninsula are already using AI, mainly through informal learning pathways, while structured institutional integration remains uneven. Structured exposure to AI is consistently associated with higher self-perceived knowledge, greater use, and more positive attitudes. These results suggest that deliberate curricular integration and guided AI literacy initiatives are important to prepare future veterinarians for responsible and effective use of AI technologies. - Source: PubMed
Publication date: 2026/06/17
Oropesa Ana LourdesMendo-Lázaro SantiagoGonzalez AntonioLeón-Del-Barco BenitoTapia José Antonio - The objective of the current study is to identify the empathy levels and attitudes of nurses who work in surgical clinics toward patients with disabilities and to investigate the correlation between these two variables. This cross-sectional, correlational-predictive study included 305 nurses working in the surgical clinics of a Training and Research Hospital affiliated with a Health Sciences University in Türkiye. The research data were collected using a Sociodemographic Information Form, the Jefferson Empathy Scale (JES), and the Disability Attitudes in Health Care Scale (DAHC) between February and April 2026. Descriptive statistics, Pearson's correlation analysis, POMP (%) score graph, eta-squared (η) effect size, independent samples t-test, one-way analysis of variance (ANOVA), and hierarchical multiple linear regression analysis were used to evaluate the data. : Participants scored an average of 102.8 points on the JES and 55.4 points on the DAHC. This value falls within Jefferson's "moderately high empathy" range (88.6-105.7), and the mean attitude score was also found to increase positively. A positive, moderate, and statistically significant correlation was found between the JES and the DAHC (r = 0.520, < 0.001). In the regression analysis, the explanatory power increased from 12.8% in Model 1 to 18.8% in Model 2 and to 35% in Model 3 (ΔR = 0.160). Considering the relative importance order of the independent variables in the final model of the regression analysis, it is understood that the strongest predictor of empathy was the DAHC (β = 0.430), followed by professional experience (β = 0.149) and education level (β = -0.145). : The present study found that attitude, education level, and professional experience were the main factors affecting the empathy level. A positive correlation was identified between empathy and attitude. Hence, the accessibility of patients with disabilities to intensive and stressful clinics such as surgical clinics, the organization of in-service training, and the integration of multidisciplinary teamwork can create equal opportunities in health care for patients with disabilities. - Source: PubMed
Publication date: 2026/06/06
Ünal HarunErfidan GültaçKümet ÖmerKoç MuratÖzlü Zeynep Karaman - Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder characterized by amyloid-β (Aβ) and tau pathology, neuroaxonal damage, and neuroinflammation. While blood biomarkers, such as tau, neurofilament light chain (NfL), and Aβ isoforms, reflect AD pathology, the systemic metabolic alterations contributing to the disease remain poorly defined. This study aims to explore associations between plasma metabolites and key protein biomarkers linked to AD pathology in a large, population-based cohort. - Source: PubMed
Publication date: 2026/06/10
Kuilman Midas MAhmad ShahzadPomp Amos CWolters Frank JKaddurah-Daouk RimaIkram M ArfanGhanbari Mohsen