Antibody CD79a _B lymphocytes JCB117
- Known as:
- Antibody CD79a _B lymphocytes JCB117
- Catalog number:
- AB01042
- Product Quantity:
- 3.0ml
- Category:
- -
- Supplier:
- Other suppliers
- Gene target:
- Antibody CD79a _B lymphocytes JCB117
Related genes to: Antibody CD79a _B lymphocytes JCB117
- Gene:
- CD79A NIH gene
- Name:
- CD79a molecule
- Previous symbol:
- IGA
- Synonyms:
- MB-1
- Chromosome:
- 19q13.2
- Locus Type:
- gene with protein product
- Date approved:
- 1992-07-31
- Date modifiied:
- 2019-04-23
Related products to: Antibody CD79a _B lymphocytes JCB117
Related articles to: Antibody CD79a _B lymphocytes JCB117
- Aggressive B-cell lymphomas with plasmablastic morphology are uncommon neoplasms that may exhibit overlapping morphologic, immunophenotypic, and genetic features of plasmablastic lymphoma (PBL) and double-hit lymphoma (DHL). Concurrent IGH::MYC and IGH::BCL2 rearrangements are rarely encountered in this setting, particularly in the testis. Here, we describe an unusual case presenting significant diagnostic challenges at the interface between PBL and DHL. - Source: PubMed
Publication date: 2026/09/07
Kim BinnariCha Hee Jeong - Oral manifestations may present as the first and only sign of lymphoma that primarily affect the oral mucosa, gingiva, and salivary glands. The purpose of this study was to analyze the scientometric characteristics and research trends of lymphoma involving the oral cavity. - Source: PubMed
Publication date: 2026/04/01
He JieShi HuanGeng Zhao - Oral lichen planus (OLP) frequently overlaps clinically and histopathologically with oral erythroleukoplakia (OEL), a high-risk oral potentially malignant disorder. OEL with lichenoid features (OEL-L) may closely mimic OLP, resulting in diagnostic uncertainty and inappropriate management. This study aimed to characterize immune and epithelial transcriptomic differences between OLP and OEL-L and to identify potential diagnostic biomarkers. - Source: PubMed
Publication date: 2026/04/01
Chang Julia Yu FongChen Jung-TsuWang Yi-Ping - Chiropterans exhibit remarkable immunological adaptations that facilitate their function as competent reservoir hosts for diverse high-consequence zoonotic viruses while maintaining apparent clinical health. The Egyptian rousette (Rousettus aegyptiacus), a frugivorous pteropodid species, represents the sole confirmed natural reservoir for Marburg and Ravn viruses (family Filoviridae), yet comprehensive characterization of its lymphoid system architecture remains absent from the literature. This investigation presents the first systematic gross, histological, and immunohistochemical atlas of lymphoid tissues in this epidemiologically critical species, encompassing primary (bone marrow, thymus) and secondary lymphoid tissues (lymph nodes, spleen, mucosa-associated lymphoid tissue). Tissues from fetal, juvenile, and adult specimens were systematically evaluated to characterize age-related variations in lymphoid architecture and cellular composition dynamics. Immunohistochemical analyses employing cross-reactive antibodies against CD3, CD79a, Iba1, and Granzyme B elucidated the spatial distribution and organizational patterns of key lymphocyte populations and antigen-presenting cells across distinct lymphoid compartments. While overall lymphoid tissue organization demonstrated conservation relative to other mammalian species, several distinctive morphological features were identified, including prominently developed splenic marginal zones, extensive gut-associated lymphoid tissue networks, and organized nasopharyngeal and bronchial lymphoid structures. These anatomical specializations likely represent species-specific evolutionary adaptations underlying viral tolerance mechanisms and immunological equilibrium maintenance during persistent viral exposure. This comprehensive atlas provides an essential foundational resource for veterinary pathologists, comparative immunologists, and infectious disease investigators conducting research with R. aegyptiacus bat populations. By establishing anatomically and immunologically detailed reference standards for lymphoid tissues in this critical reservoir species, this work supports interpretation of experimental infection studies and may help guide future investigations of host-pathogen interactions, reservoir competence, and zoonotic spillover dynamics at wildlife-human interfaces. - Source: PubMed
Publication date: 2026/08/27
Elbert Jessica AAmman Brian RSealy Tara KAtimnedi PatrickTowner Jonathan SHowerth Elizabeth W - High-grade B-cell lymphoma, not otherwise specified (HGBCL-NOS), is an aggressive mature B-cell neoplasm whose diagnosis remains challenging due to significant morphologic overlap with diffuse large B-cell lymphoma and Burkitt lymphoma, and the absence of defining molecular alterations. Aberrant antigen expression can further complicate diagnoses and may result in lineage ambiguity. We report a unique case of HGBCL-NOS with MYC rearrangement demonstrating aberrant cytoplasmic CD3 and surface CD4 expression, leading to an initial misdiagnosis as a T-cell lymphoma at an outside hospital. A 50-year-old man with a previous diagnosis of peripheral T-cell lymphoma presented to our institution with central nervous system symptoms and a persistent bladder mass. Evaluation by bladder biopsy and cerebrospinal fluid flow cytometry revealed a high-grade B-cell neoplasm with diffuse CD10 and CD79a expression, patchy CD20 positivity, strong PAX5 expression, lambda light-chain restriction, Ki-67 approaching 100%, and flow cytometry confirmed expression of cytoplasmic CD3 and dim surface CD4 expression in a clonal B-cell population. Fluorescence in situ hybridization demonstrated a t(8;14)(q24;q32) MYC::IGH rearrangement without BCL2 or BCL6 rearrangements. This extremely rare phenotype has not previously been described. This case expands the spectrum of aberrant immunophenotypes reported in both B-cell lymphomas and HGBCL-NOS and highlights the importance of comprehensive lineage assessment in lymphomas with unusual antigen expression. - Source: PubMed
Publication date: 2026/08/28
Miltchev VladimirGolardi Natalia