Rat Anti-Mouse CD202b
- Known as:
- Rat Antibody toMouse CD202b
- Catalog number:
- 129-10118
- Product Quantity:
- 25
- Category:
- -
- Supplier:
- Ray Biotech
- Gene target:
- Rat Anti-Mouse CD202b
Related genes to: Rat Anti-Mouse CD202b
- Gene:
- TEK NIH gene
- Name:
- TEK receptor tyrosine kinase
- Previous symbol:
- VMCM
- Synonyms:
- TIE2, TIE-2, VMCM1, CD202b
- Chromosome:
- 9p21.2
- Locus Type:
- gene with protein product
- Date approved:
- 1994-05-24
- Date modifiied:
- 2018-08-07
Related products to: Rat Anti-Mouse CD202b
Related articles to: Rat Anti-Mouse CD202b
- Comorbidity burden may influence perioperative outcomes in elderly patients undergoing minimally invasive resection for colorectal cancer (CRC). This study evaluated the association between the Charlson Weighted Comorbidity Index (CCI) and short-term postoperative outcomes in this population. - Source: PubMed
Publication date: 2026/06/10
Sato YuWignakumar AnjelliRogers PeterValdivieso CesarHambleton MichelleMoola MohammedBilotti MatthewBarnes SpencerPerrone CameronSipe SamanthaAbraham AbelLopez Christopherda Silva GiovannaWexner Steven D - This study sought to elucidate the antitumor mechanisms of the traditional herbal combination Astragalus-Curcuma zedoaria (A-C) in lung squamous cell carcinoma (LUSC). Drug-containing serum was prepared from mice administered an A-C decoction, and serum-absorbed bioactive components were identified using high-resolution mass spectrometry. To investigate potential targets and pathways within the tumor immune microenvironment, network pharmacology analysis was integrated with bulk transcriptomic data from TCGA-LUSC and single-cell RNA sequencing (scRNA-seq). The analytical methodologies employed included differential gene expression analysis, weighted gene co-expression network analysis (WGCNA), functional enrichment analysis, and molecular docking. The scRNA-seq data identified 22 distinct cell clusters, with correlation analysis suggesting that A-C primarily exerts its effects through vascular endothelial cells. Among the serum-derived components, demethoxycurcumin-a principal curcuminoid from C. zedoaria-demonstrated the highest binding affinity with the TEK receptor tyrosine kinase (-7.5 kcal/mol), indicating its potential role in modulating endothelial function and vascular-immune interactions. In conclusion, the A-C combination exhibits a synergistic effect in lung squamous cell carcinoma (LUSC) by modulating differentially expressed genes, with demethoxycurcumin identified as a pivotal bioactive compound targeting TEK. These results elucidate novel dual antitumor mechanisms of the A-C herbal pair, achieved through the regulation of the vascular-immune microenvironment. - Source: PubMed
Yu LuhangDong XueshanYang QianyuDou Yongqi - This retrospective study aimed to evaluate anesthesia management, intraoperative support strategies, and 60-day clinical outcomes in patients requiring surgical intervention, including fasciotomy and/or amputation, due to crush and compartment syndrome following the February 6, 2023, Kahramanmaraş earthquakes. The study also sought to identify predictors of mortality and contribute to the field of disaster medicine. - Source: PubMed
Taygurt Tugba NurErdem GökhanTaygurt SüleymanKoç Muhammed Nezih - Early-onset appendiceal cancer (EOAC), diagnosed before age 50, accounts for approximately 30% of all appendiceal malignancies. Its clinical profile, treatment strategies, and outcomes remain underexplored compared to late-onset disease. This study aimed to assess demographics, disease profile, management, and outcomes of EOAC. - Source: PubMed
Publication date: 2026/06/05
Emile Sameh HanyWignakumar AnjelliGaroufalia ZoeWexner Steven D - The sluggish kinetics of the oxygen reduction reaction (ORR) and the high cost of Pt-based catalysts remain major barriers for alkaline fuel cell (AFC) technologies. Here we report a Cu-decorated CoO@Pd catalyst in which atomic-to-subnanometer CuO species reconstruct the Pd-Co-Cu heterointerface and enable a cooperative multi-site ORR pathway. Structural and spectroscopic analyses reveal that low Cu loading produces atomically dispersed CuO motifs that enrich oxygen vacancies (O)s, preserve metallic Pd, and stabilize oxygen-deficient Co centers. Operando PFY-XANES/EXAFS further uncovers a synergistic mechanism in which Os around Cu serve as rapid O activation sites, Pd mediates lateral *O spillover, and Os around Co act as the primary *O reduction centers. This division of labor maximizes four-electron ORR kinetics, yielding a on-set potential of 0.935 V and a mass activity (MA) of ∼1.6 × 10 mA mg without decay for 50k potential cycles, surpassing commercial Pt/C by over two orders of magnitude. When integrated into AFCs, the optimized catalyst (CPCu-1) delivers a peak power density of ∼430 mW cm , approximately 60% higher than Pt/C, and exhibits a characteristic three-stage durability governed by dynamic CuO-CoO interface reconstruction. These findings establish atomic CuO interface engineering strategy for designing high-performance, noble-metal-efficient ORR catalysts. - Source: PubMed
Publication date: 2026/06/04
Hsu Yang-YangFan Ching-HuaWang Kuan-WenWang Kuang-KuoHiraoka NozomuIshii HirofumiChan Ting-ShanChen Po-ChunChen Tsan-Yao