BDNF
- Known as:
- BDNF
- Catalog number:
- PA1014
- Product Quantity:
- 100μg
- Category:
- -
- Supplier:
- SDlabs
- Gene target:
- BDNF
Related genes to: BDNF
- Gene:
- BDNF NIH gene
- Name:
- brain derived neurotrophic factor
- Previous symbol:
- -
- Synonyms:
- -
- Chromosome:
- 11p14.1
- Locus Type:
- gene with protein product
- Date approved:
- 1991-01-15
- Date modifiied:
- 2016-06-01
- Gene:
- BDNF-AS NIH gene
- Name:
- BDNF antisense RNA
- Previous symbol:
- BDNFOS
- Synonyms:
- BT2A, BT2B, BT2C, BT2D, NCRNA00049, BDNF-AS1, BDNFAS
- Chromosome:
- 11p14.1
- Locus Type:
- RNA, long non-coding
- Date approved:
- 2005-02-01
- Date modifiied:
- 2017-08-09
Related products to: BDNF
Related articles to: BDNF
- Brain-derived neurotrophic factor (BDNF), a critical modulator of neuroplasticity, has been strongly implicated in the pathophysiology of major depressive disorder (MDD). Non-invasive brain stimulation (NIBS), including repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS), shows therapeutic promise for MDD. However, their impact on peripheral BDNF levels remains inconclusive. - Source: PubMed
Publication date: 2026/08/06
Ni JingQiao Meng-XuanLin Yun-GeYu HuaLi Tao - Neurotrophins, including brain-derived neurotrophic factor (BDNF) and neurotrophin-4 (NT-4), have been associated with the development of bronchopulmonary dysplasia (BPD) in preterm infants. - Source: PubMed
Publication date: 2026/08/07
Stephenson NicoleYi Joe XiaotongGower W AdamJensen Elizabeth TJackson WesleyLaughon MatthewO'Shea T Michael - Endometriosis affects about 10% of reproductive-age women, causing pelvic pain and infertility. Its progression involves angiogenesis and neurovascular innervation, mediated by vascular endothelial growth factor (VEGF) and brain-derived neurotrophic factor (BDNF). Clove leaf extract may suppress lesion growth by reducing these pathways through antioxidant and anti-inflammatory actions. - Source: PubMed
Publication date: 2026/07/14
Mahardika Fitrianti UmayrohHendarto HendyWidjiati - Serum brain-derived neurotrophic factor (BDNF) is linked to post-stroke neuroplasticity, but its temporal dynamics and clinical relevance during early rehabilitation remain unclear. We investigated changes in serum mature BDNF, proBDNF, and matrix metalloproteinase-9 (MMP-9) during the early subacute phase of stroke and their associations with functional improvement under standardized inpatient rehabilitation. In this prospective observational study at a tertiary inpatient rehabilitation unit, 100 stroke patients were enrolled and 84 were analyzed. Serum biomarkers and clinical assessments-including the National Institutes of Health Stroke Scale (NIHSS), Korean Mini-Mental State Examination, Fugl-Meyer Assessment, and Berg Balance Scale-were obtained at baseline (T0) and after two weeks of rehabilitation (T1). Correlation and multivariable regression analyses examined relationships between biomarker changes and functional outcomes, adjusting for age, sex, time from onset, and BDNF genotype. An increase in serum mature BDNF from T0 to T1 was significantly associated with NIHSS improvement (r = -0.273, = 0.014), which persisted after multivariable adjustment (β = -0.737, = 0.009). Changes in proBDNF and MMP-9 showed no significant associations. Greater individual increases in serum mature BDNF during early subacute rehabilitation were independently associated with greater reductions in stroke severity, whereas the group-level mean did not increase over time. Serum mature BDNF may serve as a time-sensitive, objective biomarker of neurobiological recovery, potentially supporting individualized rehabilitation strategies. - Source: PubMed
Publication date: 2026/07/16
Shin SeyoungKim HeegooKim Dae HyunChang Won Hyuk - Jiao-tai-wan (JTW) is a classic formula for Heart-Kidney Disharmony insomnia, yet its mechanism in hippocampal neurons remains unclear. - Source: PubMed
Publication date: 2026/07/10
Ye WeiLin ZeYou ZihanZhu ZijianYuan Zhengzhong