DYDC1 (aa142_154)
- Known as:
- DYDC1 (aa142_154)
- Catalog number:
- Y214452
- Product Quantity:
- 200ul
- Category:
- -
- Supplier:
- ABM
- Gene target:
- DYDC1 (aa142_154)
Related genes to: DYDC1 (aa142_154)
- Gene:
- DYDC1 NIH gene
- Name:
- DPY30 domain containing 1
- Previous symbol:
- -
- Synonyms:
- bA36D19.5, DPY30D1
- Chromosome:
- 10q23.1
- Locus Type:
- gene with protein product
- Date approved:
- 2004-05-27
- Date modifiied:
- 2016-10-05
Related products to: DYDC1 (aa142_154)
(+)-Catechin C15H14O6 CAS: 154-23-4(+)-Catechin CAS: 154-23-4 Formula: C15H14O6 0.2ml Individual PCR Tubes Natural, Flat Cap0.2ml PCR Tube, Flat-Cap0.2ml PCR Tube, Flat-Cap Ultra Thin Wall0.2ml PCR Tube, Flat-Cap Ultra Thin Wall0.2ml PCR Tube, Flat-Cap Ultra Thin Wall0.2ml PCR Tube, Flat_Cap Ultra Thin Wall1,5-Anhydro-D-glucitol C6H12O5 CAS: 154-58-51,5-Anhydro-D-glucitol CAS: 154-58-5 Formula: C6H12O51,5_Anhydro_D_glucitol 1,5_Anhydro_D_glucitol1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1,Bos taurus,Bovine,Phosphoinositide phospholipase C-beta-1,Phospholipase C-beta-1,PLC-154,PLCB1,PLC-beta-11-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1,Homo sapiens,Human,KIAA0581,Phosphoinositide phospholipase C-beta-1,Phospholipase C-beta-1,Phospholipase C-I,PLC-154,PLCB1,PLC-beta-1,P1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1,Mouse,Mus musculus,Phosphoinositide phospholipase C-beta-1,Phospholipase C-beta-1,PLC-154,Plcb,Plcb1,PLC-beta-11-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1,Phosphoinositide phospholipase C-beta-1,Phospholipase C-beta-1,Phospholipase C-I,PLC-154,Plcb1,PLC-beta-1,PLC-I,Rat,Rattus norvegicus Related articles to: DYDC1 (aa142_154)
- Asthenozoospermia (ASZ) accounts for about 20-40% of male infertility, and genetic factors, contributing to 30-40% of the causes of ASZ, still need further exploration. Radial spokes (RSs), a T-shaped macromolecular complex, connect the peripheral doublet microtubules (DMTs) to a central pair (CP), forming a CP-RS-DMT structure to regulate the beat frequency and amplitude of sperm flagella. To date, many components of RSs and their functions in human sperm flagella remain unclear. - Source: PubMed
Publication date: 2025/01/23
Hu TingwenyiTang XiangrongRuan TiechaoLong ShunhuaLiu GuicenMa JingLi XueqiZhang RuoxuanHuang GuoningShen YingLin Tingting - - Source: PubMed
Publication date: 2018/11/26
Li ShuchunQiao YuanDi QianLe XiuningZhang LeiZhang XiaosongZhang ChangyongCheng JieZong ShudongKoide Samuel SMiao ShiyingWang Lingfang - Marker detection is an important task in complex disease studies. Here we provide an association rule mining (ARM) based approach for identifying integrated markers through mutual information (MI) based statistically significant feature extraction, and apply it to acute myeloid leukemia (AML) and prostate carcinoma (PC) gene expression and methylation profiles. - Source: PubMed
Publication date: 2017/11/23
Mallik SauravZhao Zhongming - Spastic paraplegia type 4 (SPG4) is the most common autosomal dominant hereditary SPG caused by mutations in the SPAST gene. We studied the four-generation pedigree of a Japanese family with autosomal dominant hereditary SPG both clinically and genetically. Twelve available family members (ten affected; two unaffected) and two spouses were enrolled in the study. The clinical features were hyperreflexia in all four limbs, spasticity of the lower extremities, impaired vibration sense, mild cognitive impairment confirmed by the Wechsler Adult Intelligence Scale-Third Edition, and peripheral neuropathy confirmed by neurophysiological examinations. All four female patients experienced miscarriages. The cerebrospinal fluid tau levels were mildly increased in two of three patients examined. Linkage analyses revealed the highest logarithm of odds score of 2.64 at 2p23-p21 where the SPAST gene is located. Mutation scanning of the entire exonic regions of the SPAST gene by direct sequencing revealed no mutations. Exonic copy number analysis by real-time quantitative polymerase chain reaction revealed heterozygous deletion of exons 1 to 4 of the SPAST gene. Breakpoint analysis showed that the centromeric breakpoint was located within intron 4 of SPAST while the telomeric breakpoint was located within intron 3 of the neighboring DPY30 gene, causing a deletion of approximately 70 kb ranging from exons 1 to 3 of DPY30 to exons 1 to 4 of SPAST. To our knowledge, this is the first report of SPG4 associated with partial deletions of both the SPAST and DPY30 genes. The partial heterozygous deletion of DPY30 could modify the phenotypic expression of SPG4 patients with this pedigree. - Source: PubMed
Publication date: 2010/09/22
Miura ShirohShibata HirokiKida HiroshiNoda KazuhitoToyama TakayukiIwasaki NaokaIwaki AkikoAyabe MitsuyoshiAizawa HisamichiTaniwaki TakayukiFukumaki Yasuyuki - The N-terminal BAR domain of endophilin has unique functions, such as affecting the curvature of the lipid membrane through its lysophosphatidic acid acyltransferase activity, binding of ATP and GTP and participating in tubulating activity. We recently demonstrated that SH3P13, a BAR domain-containing protein, assists in regulating clathrin-coated vesicle traffic that is crucial for acrosome biogenesis during spermatogenesis. DYDC1 was identified in a yeast two-hybrid screen from a human testis library by using the SH3P13 BAR domain as the bait. Consistent with the expression pattern of SH3P13, DYDC1 is exclusively expressed in the brain and testis and accumulates in the acrosome area during late stage of spermiogenesis. Here, we report that DYDC1 plays a crucial role during acrosome biogenesis. This relationship has been verified by a novel approach that involves germ cell transplantation and RNA interference. We found that knockdown of endogenous Dydc1 interfered with the formation of acrosomes, and thus spermatid differentiation during mouse spermiogenesis. These data provide important insight into the crucial process of acrosome biogenesis. In addition, our approach can also be applied to study functions of other genes related to spermatogenesis in vivo. - Source: PubMed
Publication date: 2009/07/09
Li ShuchunQiao YuanDi QianLe XiuningZhang LeiZhang XiaosongZhang ChangyongCheng JieZong ShudongKoide Samuel SMiao ShiyingWang Lingfang