DPM2
- Known as:
- DPM2
- Catalog number:
- Y214249
- Product Quantity:
- 200ul
- Category:
- -
- Supplier:
- ABM
- Gene target:
- DPM2
Related genes to: DPM2
- Gene:
- DPM2 NIH gene
- Name:
- dolichyl-phosphate mannosyltransferase subunit 2, regulatory
- Previous symbol:
- -
- Synonyms:
- MGC21559, MGC111193
- Chromosome:
- 9q34.11
- Locus Type:
- gene with protein product
- Date approved:
- 1999-02-23
- Date modifiied:
- 2016-10-05
Related products to: DPM2
Bos taurus,Bovine,Dolichol phosphate-mannose biosynthesis regulatory protein,DPM2Bovine Dolichol phosphate-mannose biosynthesis regulatory protein(DPM2) ELISA kitBovine Dolichol phosphate-mannose biosynthesis regulatory protein(DPM2) ELISA kit SpeciesBovineBovine dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit (DPM2) ELISA kit, Species Bovine, Sample Type serum, plasmaDolichol phosphate-mannose biosynthesis regulatory protein,DPM2,Homo sapiens,Human,My026Dolichol phosphate-mannose biosynthesis regulatory protein,Dpm2,Mouse,Mus musculusDolichol phosphate-mannose biosynthesis regulatory protein,Dpm2,Rat,Rattus norvegicusDPH5 Gene DPH5 homolog (S. cerevisiae)DPM2 antibody Isotype IgG Host GoatDPM2 AntibodyDPM2 (C-term) antibody Isotype Ig Host rabbitDPM2 (C_term)DPM2 (C_term)Dpm2 (mouse)Dpm2 (mouse) Antibody Related articles to: DPM2
- This study reports the hemisynthesis of two novel dipyrromethanes ( and ) from ethyl 1,2-dimethyl-1H-pyrrole-3-carboxylate and natural aldehydes: perillaldehyde from and cuminaldehyde from cumin seed essential oil. The compounds were synthesized a double Friedel-Crafts reaction under two catalytic systems: (i) water/ethanol (1:1 v/v) with 0.18 M HCl, and (ii) iodine-catalyzed chloroform. Structural elucidation was achieved using H NMR,C NMR, HSQC, HMBC, and HR-MS. Both derivatives showed significant inhibitory activity against AChE and BChE. was more active against AChE (IC = 22.6 ± 0.06 μM) than (IC = 51 ± 1.74 μM), and comparable to Galantamine (IC = 21.81 ± 1.15 μM). Regarding BChE, (IC = 115 ± 1.91 μM) exhibited greater inhibitory potency than (IC = 230.41 ± 0.75 μM), and remained close to Galantamine (IC = 120.93 ± 1.99 μM). analysis supported their potential as anti-Alzheimer's agents. - Source: PubMed
Publication date: 2026/03/27
Maadadi RamziBoukentoucha ChafaiBazine IsmaheneMenacer RafikBensouici ChawkiPevzner LeonidPetrov MikhailStepakov AlexanderAbou Dib AnthonyHarakat Dominique - Muscle-Eye-Brain disease (MEB) is a dystroglycanopathy that belongs to the congenital muscular dystrophies. Central nervous system manifestations include congenital brain abnormalities, neurodevelopmental delay, and epilepsy, making it a rare but important cause of developmental and epileptic encephalopathy. This systematic review aims to explore all current literature data regarding clinical and electroencephalographic features of MEB cases with epilepsy. - Source: PubMed
Publication date: 2026/03/07
Kalampokini StefaniaPityrigkas EvripidisLiouta EleniPepe GeorgiaPoulidou VasilikiSpilioti MarthaKimiskidis Vasilios K - Congenital disorders of glycosylation (CDG) are a complex and heterogeneous family of rare metabolic diseases that affect protein and lipid glycosylation and glycosylphosphatidylinositol synthesis. These disorders can affect multiple organs, leading to a broad spectrum of symptoms that vary among different CDG subtypes and between individuals with same type of CDG. This study aimed to investigate the genetic variants, molecular etiologies, and clinical features of 20 Chinese patients diagnosed with CDG. - Source: PubMed
Publication date: 2025/12/23
Zhao PeiweiTan LiMeng QingjieZhang LeiHuang YufengZhang XiankaiHu YanqiuZhou ShiqiongHe Xuelian - This study investigates how dolichol phosphate mannose synthase (DPMS) subunits DPM1/2/3 affect oral squamous cell carcinoma (OSCC) prognosis and their associations with OSCC. - Source: PubMed
Publication date: 2025/10/17
Liu HongyuWu Buling - The polyisoprenoid lipid dolichol is critical for eukaryotic glycosylation. It is used as the membrane anchor for mono- or oligosaccharides transferred during N-glycosylation, O/C-mannosylation and glycosylphosphatidylinositol anchor biosynthesis. Disorders affecting the synthesis or utilization of dolichol cause defective glycosylation and are therefore classified as Congenital Disorders of Glycosylation (CDG). CDG are a group of approximately 200 mostly autosomal recessive inherited metabolic disorders characterized by defective glycosylation of proteins and lipids. Through recently identified defects, we have gained new insights into dolichol synthesis, important to understand the pathological mechanisms in affected patients. This review provides an overview of dolichol synthesis and utilization and an update on CDG caused by disruption of these processes. Finally, we discuss the existing biomarkers for diagnosis of these disorders and the potential for effective therapies. - Source: PubMed
Publication date: 2025/08/22
Pieters ElineJaeken JaakWilson Matthew P