CAMK1D
- Known as:
- CAMK1D
- Catalog number:
- Y214231
- Product Quantity:
- 200ul
- Category:
- -
- Supplier:
- ABM
- Gene target:
- CAMK1D
Related genes to: CAMK1D
- Gene:
- CAMK1D NIH gene
- Name:
- calcium/calmodulin dependent protein kinase ID
- Previous symbol:
- -
- Synonyms:
- CKLiK
- Chromosome:
- 10p13
- Locus Type:
- gene with protein product
- Date approved:
- 2003-11-05
- Date modifiied:
- 2015-12-04
Related products to: CAMK1D
Related articles to: CAMK1D
- Pigs are one of the most important livestock species for providing meat products in the world. Deciphering the genetic architecture of feed efficiency-related traits is beneficial to improve the genetic progress of these traits and save the total cost of pork production. However, the genetic architecture of feed efficiency-related traits remains unclear. - Source: PubMed
Publication date: 2026/02/27
Lin ChangguangChen QiuyongLiu YaxuanCai WeiHuang TaoZhou YiLin JinyuZhou LunjiangChen Xinzhu - The gut microbiome is closely associated with malignant tumors; however the specific mechanisms by which it contributes to the development of lung adenocarcinoma remain unclear. In this study, we performed a two-sample bidirectional Mendelian randomization (MR) analysis to assess the causal relationship between the gut microbiome and lung adenocarcinoma. By identifying single nucleotide polymorphism markers linked to gut microbiome species, we aimed to discover potential biomarkers for lung adenocarcinoma. These findings may offer new insights into the role of the gut microbiome in the prevention and treatment of lung adenocarcinoma. - Source: PubMed
Publication date: 2026/03/18
Yan NuoZhang YangWang SilinHu ShengRuan LianchengWang YunzheFeng WeiqiangXiong WenxunZhang WenxiongWei YipingYao Chuan - Diabetic kidney disease (DKD) is a leading cause of end-stage renal disease (ESRD), accelerates age-related decline in estimated glomerular filtration rate (eGFR), leading to a markedly increased prevalence of DKD among elderly diabetic patients. Recent studies suggest that immune dysregulation plays a pivotal role in DKD progression; however, the cellular and molecular mechanisms linking aging, immune infiltration, and DKD remain unclear. - Source: PubMed
Publication date: 2026/02/13
Zhu PeiqiTang RuijieZhou YapingHe YiningZhao JingLiu ZhengxinZhao YingHe Weiming - Metabolic syndromes (MeS), marked by central obesity, high blood pressure, abnormal cholesterol and blood sugar, are key cardiovascular disease (especially coronary artery disease, CAD) risk factors. Genetic studies show MeS-CAD genetic overlap, indicating shared biological pathways. We used Summary-data-based Mendelian Randomization (SMR), Bayesian colocalization (with large GWAS summary stats for MeS/CAD and cis-eQTL data from 3 tissues) and Transcriptome-Wide Association Study (TWAS). We also investigated the effects of gene knockout on mouse phenotypes. SMR found 886/737/192 shared genes in blood/brain cortex/liver; colocalization identified 11/13/5 shared causal genes in these tissues and 46 shared loci (e.g., CAMK1D, OR=1.11; AGPAT1, OR=1.13; FDR<0.05). Moreover, knocking out these genes in mice affected metabolism, adipose tissue, cardiovascular function, glucose homeostasis, and the fat/muscle balance. This study identified common regulatory genes between MeS and CAD, suggesting that targeted therapies or interventions could potentially address both conditions simultaneously, offering prospects for more integrated treatment strategies. - Source: PubMed
Publication date: 2025/12/30
Yi PengchengYin QuantingZhang HuanhuanYang ChunhuaZhu YanpingXia ZhenhongXu FuyiMi Jia - Hypertension remains a significant global health issue. Low-density neutrophils (LDNs), a subset of neutrophils, contribute to vascular injury through immune activation. This study aimed to explore the effects of valsartan on LDNs in hypertension and to elucidate the molecular mechanisms underlying their role in therapeutic response. Newly diagnosed hypertensive patients received 80 mg/day valsartan for one month. Single-cell RNA sequencing was performed on peripheral blood mononuclear cells (PBMCs) collected before and after treatment. Mendelian randomization (MR) analysis was used to identify genes associated with valsartan response among the differentially expressed genes. Eleven cell subpopulations were identified, including four distinct LDN subtypes: CAMK1D, PI3, ISG15, and S100A12. Valsartan treatment reduced immune activation-related transcripts in LDNs, with decreased CAMK1D and increased PI3 expression. Lower MMP9 transcript levels in the PI3 subtype were linked to limited differentiation of LDNs into the CAMK1D subtype, with a preference for retention in the PI3 subtype, potentially contributing to valsartan's ehanced efficacy. Theses findings highlight CAMK1D and PI3 as LDN-related genes influencing valsartan response in hypertension, offering a foundation for future functional studies. - Source: PubMed
Publication date: 2026/01/31
Huang Bang-BangYu XingCai Zhi-DianWu Jian-MinCai Wen-QinPan MinHuang YunChen Yi-JunYu Ming-ZhongQiu Yi-FeiLin LiLian Gui-LiXie Liang-DiLuo Li