TUSC4 _ NPRL2 (aa 140 to 151)
- Known as:
- TUSC4 _ NPRL2 (aa 140 151)
- Catalog number:
- Y213850
- Product Quantity:
- 200ul
- Category:
- -
- Supplier:
- ABM
- Gene target:
- TUSC4 _ NPRL2 ( 140 151)
Related genes to: TUSC4 _ NPRL2 (aa 140 to 151)
- Gene:
- ANKRD16 NIH gene
- Name:
- ankyrin repeat domain 16
- Previous symbol:
- -
- Synonyms:
- DKFZP434N1511
- Chromosome:
- 10p15.1
- Locus Type:
- gene with protein product
- Date approved:
- 2003-11-19
- Date modifiied:
- 2016-10-17
- Gene:
- APBA2 NIH gene
- Name:
- amyloid beta precursor protein binding family A member 2
- Previous symbol:
- X11L, MINT2
- Synonyms:
- D15S1518E, LIN-10, MGC:14091, HsT16821
- Chromosome:
- 15q13.1
- Locus Type:
- gene with protein product
- Date approved:
- 1997-06-25
- Date modifiied:
- 2016-10-05
- Gene:
- BOK-AS1 NIH gene
- Name:
- BOK antisense RNA 1
- Previous symbol:
- BOKAS
- Synonyms:
- NCRNA00151, NAToB
- Chromosome:
- 2q37.3
- Locus Type:
- RNA, long non-coding
- Date approved:
- 2009-07-29
- Date modifiied:
- 2014-01-23
- Gene:
- C19orf48 NIH gene
- Name:
- chromosome 19 open reading frame 48
- Previous symbol:
- -
- Synonyms:
- MGC13170, BC006151
- Chromosome:
- 19q13.33
- Locus Type:
- gene with protein product
- Date approved:
- 2006-07-12
- Date modifiied:
- 2017-04-20
- Gene:
- CEP72 NIH gene
- Name:
- centrosomal protein 72
- Previous symbol:
- -
- Synonyms:
- KIAA1519, FLJ10565
- Chromosome:
- 5p15.33
- Locus Type:
- gene with protein product
- Date approved:
- 2005-12-01
- Date modifiied:
- 2016-03-30
Related products to: TUSC4 _ NPRL2 (aa 140 to 151)
(2E)-3-Phenyl-2-propenoic Acid CAS: 140-10-3 Formula: C9H8O2(4_(Dimethylamino)phenyl)diazinesulfoni Dexon(TM)(Leu144,Arg147)-Myelin Proteolipid Protein (139-151) 98% C67H110N20O17 CAS:(Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat)
(Ser140)-Lipophilin (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat), (Ser140)-PLP (139-151(Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated), human, bovine, dog, mouse, rat(Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated), human, bovine, dog, mouse, rat(Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated), human, bovine, dog, mouse, rat(Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated), human, bovine, dog, mouse, rat1,3_Di Methoxy Benzene 1,3_Di Methoxy Benzen1,3_Dimethoxybenzene 1,3_Dimethoxybenzene1,4-Dinitrosopiperazine C4H8N4O2 CAS: 140-79-4 1,4-Dinitrosopiperazine CAS: 140-79-4 Formula: C4H8N4O2 1,4_Dihydroxybutan_2_one _1,5-DIPHENYL CARBAZIDE (Redox Indicator) CAS: 140-22-71,5-DIPHENYL CARBAZIDE (Redox Indicator) CAS: 140-22-7 Related articles to: TUSC4 _ NPRL2 (aa 140 to 151)
- Epstein-Barr virus-positive inflammatory follicular dendritic cell sarcoma (EBV+ IFDCS), recently reclassified in the 5th edition of the WHO classification of lymphoid neoplasms, is a rare mesenchymal and dendritic cell tumor distinct from conventional follicular dendritic cell sarcoma (FDCS) in cellular origin and clinicopathological features. To address this, we present the largest sequencing cohort of EBV+ IFDCS to date, combining targeted next-generation sequencing (NGS) of 12 cases and whole-exome sequencing (WES) of 3 cases. This study aims to elucidate the molecular characteristics of EBV+ IFDCS to better understand its pathogenesis and identify potential therapeutic targets. - Source: PubMed
Publication date: 2026/06/29
You ZhijieChen SiqiChen XinChen XinWang Chen - This study aimed to investigate the mechanisms by which Citrus aurantium honey modulates gastrointestinal motility, inflammation, and barrier function using network pharmacology and Drosophila melanogaster models. - Source: PubMed
Publication date: 2026/06/01
Wan WenqiHuang RuiguangCao ShuqiongPan LuxiaZhang WenkaiJiang WujunLiu Zhiyong - To determine the diagnostic yield of genetic testing in patients undergoing presurgical evaluation for epilepsy. - Source: PubMed
Publication date: 2026/05/20
Jünemann ClaraStuart AmandaKaur NavprabhjotWiebe SamuelJette NathalieSingh ShailyBorlot FelippeKnake Susanne Billie Au Ping YeeKlein Karl Martin - The mTOR pathway is important for neurodevelopment. The GATOR1 complex, composed of DEPDC5, NPRL2, and NPRL3, functions as a negative regulator of mTORC1 activity and pathogenic variants in the genes which comprise this complex cause focal epilepsy and malformation of cortical development, all named as GATORopathies. While focal cortical dysplasia is commonly reported, the full spectrum of associated neuroimaging findings remains incompletely defined. - Source: PubMed
Publication date: 2026/05/18
Rb RevanthAjith AdityaNayak AbhishekRadhakrishnan AshalathaThomas BejoyKesavadas Chandrasekharan - Acute activation of mTORC1 by amino acids (AAs) is pivotal for growth regulation, yet it remains unclear how the intracellular nutrient-sensing machinery might be rewired by environmental cues to execute distinct functions. Here we report that, despite nutrient insufficiency, cancer-intrinsic AA-sensing mTORC1 signalling is hijacked by inflammatory cytokines in the tumour microenvironment (TME). ZBTB5 translates inflammatory signals to restore mTORC1 pathway via disrupting the GATOR1 complex. Mechanistically, inflammatory cues promote phosphorylation of ZBTB5-S127, thereby recruiting the Cullin3 E3 ubiquitin ligase to degrade NPRL2 within GATOR1 and reactivate mTORC1 signalling. Consequently, tumoural AA uptake is boosted to exacerbate nutrient restriction and death of CD8 T cells, leading to immunoevasion, tumour progression and inferior response to immune-checkpoint inhibitors. As such, blocking ZBTB5-pS127 ameliorates primary and acquired resistance to checkpoint blockade. Thus, targeting aberrant nutrient-sensing via the ZBTB5-pS127-mTORC1 axis represents a proof-of-concept strategy to sensitize cancer immunotherapy by alleviating AA restriction in the TME. - Source: PubMed
Publication date: 2026/04/03
Xiang JunyuWang TaoTian ShuoranLi JinyangLuo MengyunWang YuzhuDu AibeiChen XuTian FanxuanWang LeiZhang YongchaoHan MengyiHou WenqingWang XinyuHou TaoLiu QinChen DongfengWen LiangzhiQin ZhongyiLi XianfengJiang CongZhang QiaoqiaoLiu PengdaBian XiuwuWei WenyiWang Bin