TMP21 _ TMED10
- Known as:
- TMP21 _ TMED10
- Catalog number:
- Y213508
- Product Quantity:
- 200ul
- Category:
- -
- Supplier:
- ABM
- Gene target:
- TMP21 _ TMED10
Related genes to: TMP21 _ TMED10
- Gene:
- TMED10 NIH gene
- Name:
- transmembrane p24 trafficking protein 10
- Previous symbol:
- -
- Synonyms:
- TMP21, P24(DELTA), p24d1, p24delta1, p23
- Chromosome:
- 14q24.3
- Locus Type:
- gene with protein product
- Date approved:
- 2005-08-26
- Date modifiied:
- 2015-08-11
- Gene:
- TMED10P1 NIH gene
- Name:
- transmembrane p24 trafficking protein 10 pseudogene 1
- Previous symbol:
- TMED10P
- Synonyms:
- Tmp21-II
- Chromosome:
- 8q24.3
- Locus Type:
- pseudogene
- Date approved:
- 2005-08-26
- Date modifiied:
- 2016-01-28
Related products to: TMP21 _ TMED10
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- Tmp21 (p23) is involved in biosynthetic transport from the endoplasmic reticulum to the Golgi complex. We have recently characterized two cDNA-variants of human Tmp21, the Tmp21-isoforms-I and -II. Because of the lack of cDNA sequence data and protein expression data, it was not clear if Tmp21-II encodes a functional Tmp21-protein. Here we describe the cloning of the full length human Tmp21-II transcript. The putative open reading frame of Tmp21-II contains a reading frame jump and a nonsense mutation in comparison to all other Tmp21-I (p23) members. Our data indicate that hum-Tmp21-II is transcribed, but not translated. We conclude that Tmp21-II cDNA derives from a neutral pseudogene, which originates from a duplication event of the human Tmp21-isoform-I. - Source: PubMed
Hörer JBlum RFeick PNastainczyk WSchulz I